Prevalence of and Risk Factors for Age-Related and Anterior Polar Cataracts in a Korean Population

Na, Kyungsun; Park, Yong Gyu; Han, Kyungdo; Mok, Jeewon; Joo, Choun‐Ki

doi:10.1371/journal.pone.0096461

Cited by 17 publications

(21 citation statements)

References 22 publications

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“…Previous studies have showed that ARC occurs more common in female than male[ 3 , 37 , 38 , 39 , 40 ]. In our present study, female gender was also found as independent risk factors for cortical and nuclear cataract.…”

Section: Discussionmentioning

confidence: 99%

The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report

Tang

et al. 2015

PLoS ONE

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PurposeTo study the relationship between outdoor activity and risk of age-related cataract (ARC) in a rural population of Taizhou Eye Study (phrase 1 report).MethodA population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012. Participants underwent detailed ophthalmologic examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp and fundus examinations as well as questionnaires about previous outdoor activity and sunlight protection methods. ARC was recorded by LOCSⅢ classification system. The prevalence of cortical, nuclear and posterior subcapsular cataract were assessed separately for the risk factors and its association with outdoor activity.ResultsOf all 2006 eligible participants, 883 (44.0%) adults were diagnosed with ARC. The prevalence rates of cortical, nuclear and posterior subcapsular cataract per person were 41.4%, 30.4% and 1.5%, respectively. Women had a higher tendency of nuclear and cortical cataract than men (OR = 1.559, 95% CI 1.204–2.019 and OR = 1.862, 95% CI 1.456–2.380, respectively). Adults with high myopia had a higher prevalence of nuclear cataract than adults without that (OR = 2.528, 95% CI 1.055–6.062). Multivariable logistic regression revealed that age was risk factor of nuclear (OR = 1.190, 95% CI 1.167–1.213) and cortical (OR = 1.203, 95% CI 1.181–1.226) cataract; eyes with fundus diseases was risk factor of posterior subcapsular cataract (OR = 6.529, 95% CI 2.512–16.970). Outdoor activity was an independent risk factor of cortical cataract (OR = 1.043, 95% CI 1.004–1.083). The risk of cortical cataract increased 4.3% (95% CI 0.4%-8.3%) when outdoor activity time increased every one hour. Furthermore, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year.ConclusionOutdoor activity was an independent risk factor for cortical cataract, but was not risk factor for nuclear and posterior subcapsular cataract. The risk of cortical cataract increased 4.3% when outdoor activity time increased every one hour. In addition, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year.

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Section: Discussionmentioning

confidence: 99%

The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report

Tang

et al. 2015

PLoS ONE

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“…A structured eye examination was performed using a slit-lamp (Haag-Streit model BQ-900; Haag-Streit AG, Koeniz, Switzerland) to evaluate the participants’ cataract status [28]. The standard Lens Opacities Classification System III (LOCS III) was used to categorize the type of cataract.…”

Section: Methodsmentioning

confidence: 99%

Age-Related Cataract Is Associated with Elevated Serum Immunoglobulin E Levels in the South Korean Population: A Cross-Sectional Study

2016

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BackgroundPrevious research has suggested that immunoglobulin E (IgE)-mediated events lead to several chronic diseases. We investigated the association between allergic conditions and age-related cataracts in the South Korean adult population.MethodsA cross-sectional study was performed using data obtained from 1,170 participants aged 40 years or older who were enrolled in the Korean National Health and Nutrition Examination Survey 2010. Multivariable logistic regression was used to examine the relationship between age-related cataracts and allergic conditions, including total serum IgE and allergen-specific serum IgE levels, after adjustment for potential confounders (age, sex, alcohol consumption, smoking, sun exposure, blood pressure, plasma glucose and cholesterol levels, as well as histories of asthma, atopic dermatitis, and rheumatoid arthritis).ResultsAfter adjusting for potential confounders, the odds ratio (OR) for age-related cataract was greater in participants with higher total serum IgE levels (OR = 1.37; P = 0.044). In particular, increased IgE levels were significantly associated with nuclear cataract (OR = 1.42; P = 0.032). However, allergen-specific serum IgE levels did not differ significantly between groups. In the trend analysis, no significant relationship was observed between serum IgE and any type of age-related cataract.ConclusionIncreased total serum IgE level is independently associated with age-related cataracts after adjustment for confounding factors.

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“…[22][23][24][25][26] Briefly, ophthalmology residents performed comprehensive slitlamp eye examinations using a BQ 900 slitlamp (Haag-Streit AG). The standard Lens Opacities Classification Systems III (LOCS III) was used to assess cataracts.…”

Section: Age-related Cataract Assessmentsmentioning

confidence: 99%

Association between serum 25-hydroxyvitamin D levels and age-related cataracts

Jee

Kim

2015

Journal of Cataract and Refractive Surgery

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Prevalence of and Risk Factors for Age-Related and Anterior Polar Cataracts in a Korean Population

Cited by 17 publications

References 22 publications

The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report

The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report

Age-Related Cataract Is Associated with Elevated Serum Immunoglobulin E Levels in the South Korean Population: A Cross-Sectional Study

Association between serum 25-hydroxyvitamin D levels and age-related cataracts

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