Prevalence of, and Risk Factors for, Chronic Idiopathic Constipation in the Community: Systematic Review and Meta-analysis

Suares, Nicole C; Ford, Alexander C

doi:10.1038/ajg.2011.164

Cited by 708 publications

(641 citation statements)

References 56 publications

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“…7 Similar results were reported in other studies where the prevalence of FC varied from 2.6% to 30.7% of the general population. 8,15,16 The dichotomy in the data is due to the reason that in our study, the subtypes of constipation in already diagnosed constipated patients has been studied, unlike reported literature which has assessed the prevalence of constipation subtypes in the community at large.…”

Section: Discussionsupporting

confidence: 80%

“…Hence, systematic evaluations are better rather than relying on patient to volunteer information related to their specific symptoms for better management of these patients. 2,7,8 Little is known about the epidemiology and clinical subtypes of constipation in the general Indian constipated population. Hence, the present study was conducted to evaluate the prevalence of FC and IBS-C in Indian constipated patients along with assessment of their demographic, socioeconomic, lifestyle and dietary habits, usage of constipation-related medications and comorbid conditions.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of functional constipation and constipation-predominant irritable bowel syndrome in Indian patients with constipation

Rooprai

Bhat

Sainani³

et al. 2017

Int J Basic Clin Pharmacol

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Background: Evaluate prevalence of functional constipation (FC) and irritable bowel syndrome-constipation (IBS-C) in Indian constipated patients and assess their demographic/socio-economic/clinical characteristics.Methods: Patients (≥18 years) who visited their general physician with symptoms of constipation (Rome III criteria for FC or IBS-C as per physician assessment) and willing to participate were enrolled in this prospective, clinical-epidemiological study. Demographic, socioeconomic status, lifestyle and dietary habits, comorbid conditions, treatment history, concomitant medications, stool form (Bristol stool form scale), severity of constipation (constipation scoring system [CSS]), constipation-related symptoms (patient assessment of constipation symptoms [PAC-SYM]) and quality of life (patient assessment of constipation-quality of life questionnaire [PAC-QoL]) were recorded.Results: Out of 925 constipated patients, 75.6% were diagnosed with FC against 24.4% with IBS-C (P < 0.0001). Patients of both subtypes had high average scores of PAC-SYM (FC: 27.1 ± 6; IBS-C: 30.1 ± 4.9) and CSS (FC: 8.4 ± 3.1; IBS-C: 11.2 ± 3), leading to high PAC-QoL score (FC: 38.1 ± 16.8; IBS-C: 42.2 ± 13.6). Hypertension (16%) and diabetes (10%) in patients with FC while acid peptic disorders (21.7%) amongst IBS-C patients were the most common comorbid conditions observed. Laxatives were the most common medication used; osmotic (32.6% versus 40.7%) and bulk laxatives (22.8% versus 37.4%) were the commonest laxatives. However, about 1/5th patients of FC were using home remedies.Conclusions: There was a higher prevalence of FC over IBS-C in Indian constipated patients; both subtypes had high frequency and severity of constipation-related symptoms and poor QoL.

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Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Prevalence of functional constipation and constipation-predominant irritable bowel syndrome in Indian patients with constipation

Rooprai

Bhat

Sainani³

et al. 2017

Int J Basic Clin Pharmacol

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“…Constipation appears to be more common among women; [4,10,11] in one Australian study, [12] the prevalence of constipation was 24% in middle-aged women. However, the higher prevalence in women has been questioned by McCrea et al [11] that suggested that the higher prevalence in women could be due to women being more prone to report symptoms and to participate in research.…”

Section: Introductionmentioning

confidence: 99%

An interview study of the experiences of middle-aged women living with constipation

Lämås

Anundsson²,

Stare³

et al. 2014

Clinical Nursing Studies

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Introduction: Constipation is relatively common, especially among women, but little is known about the experience of living with constipation. Aim: To explore the experiences of middle-aged women living with constipation. Design: A qualitative, descriptive design. Result: The women described being constipated as being alone in an excruciating condition where life alternated between feeling tormented and feeling released, and this condition evoked feelings of stress and anxiety. Difficulties in discussing constipation and a lack of support meant that they were alone in their struggle and they felt humiliated when seeking healthcare services. Life was seen as an endless struggle between being mastered by the bowel and mastering the bowel. Conclusion:Even though data has been collected more than five years ago, the experiences described by the women are deemed to be highly valid for today. It is essential that fundamental needs like elimination are satisfied, but constipation problems seems to be neglected in the healthcare system. It is important, therefore, that patients' complaints are taken seriously.

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“…Estimates of the prevalence of constipation range from 10% to 15% in North America. 1 In the survey administered to Asians, the prevalence of chronic constipation was reported as 15-23% of female respondents and 11% of male respondents 2,3 and the prevalence of self-reported constipation was 16.5% in the general population and 9.2% of 'functional constipation' according to the Rome II criteria. 4 Constipation substantially affects the quality of life in that 70% of respondents feel its disruption to their day-to-day activities.…”

Section: Introductionmentioning

confidence: 99%

Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

Shin

Jung

Lee

et al. 2016

J Neurogastroenterol Motil

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The Korean Society of Neurogastroenterology and Motility first published guidelines for chronic constipation in 2005 and was updated in 2011. Although the guidelines were updated using evidence-based process, they lacked multidisciplinary participation and did not include a diagnostic approach for chronic constipation. This article includes guidelines for diagnosis and treatment of chronic constipation to realistically fit the situation in Korea and to be applicable to clinical practice. The guideline development was based upon the adaptation method because research evidence was limited in Korea, and an organized multidisciplinary group carried out systematical literature review and series of evidence-based evaluations. Six guidelines were selected using the Appraisal of Guidelines for Research & Evaluation (AGREE) II process. A total 37 recommendations were adopted, including 4 concerning the definition and risk factors of chronic constipation, 8 regarding diagnoses, and 25 regarding treatments. The guidelines are intended to help primary physicians and general health professionals in clinical practice in Korea, to provide the principles of medical treatment to medical students, residents, and other healthcare professionals, and to help patients for choosing medical services based on the information. These guidelines will be updated and revised periodically to reflect new diagnostic and therapeutic methods.

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Prevalence of, and Risk Factors for, Chronic Idiopathic Constipation in the Community: Systematic Review and Meta-analysis

Abstract: Pooled prevalence of CIC in the community was 14%, and of similar magnitude in most geographical regions. Rates were higher in women, older individuals, and those of lower socioeconomic status. Presence of IBS was strongly associated with CIC.

Cited by 708 publications

References 56 publications

Prevalence of functional constipation and constipation-predominant irritable bowel syndrome in Indian patients with constipation

Prevalence of functional constipation and constipation-predominant irritable bowel syndrome in Indian patients with constipation

An interview study of the experiences of middle-aged women living with constipation

Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

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