Prevalence of and predictive factors for nonalcoholic fatty liver disease in Sudanese individuals with type 2 diabetes: Is metabolic syndrome the culprit?

Almobarak, Ahmed O.; Barakat, Salma; Suliman, Eltayeb A.; Elmadhoun, Wadie M; Mohamed, Nabeel A.; Abobaker, Israa O.; Noor, Sufian K.; Bushara, Sarra O; Ahmed, Mohamed H.

doi:10.1016/j.ajg.2015.06.001

Cited by 36 publications

(29 citation statements)

References 31 publications

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“…We have previously determined that central obesity was risk factor for diabetes in Sudanese population (21). In addition, central obesity is also risk (29). Importantly, a 10 cm increase in waist circumference and waist-to-height ratio of >0.5 were associated with a significant 1.26 (India) to 1.77 (Finland), and 1.68 (China, Spain) to 5.40 (Finland) times higher odds for DM respectively (30).…”

Section: Discussionmentioning

confidence: 99%

Obesity among Sudanese adults with diabetes: a population-based survey

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Obesity among Sudanese adults with diabetes: a population-based survey

et al. 2017

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“…We have recently shown that the prevalence of NAFLD among individuals with type 2 diabetes living in the capital Khartoum was approximately 50%, whereas the prevalence of NAFLD among non-diabetic individuals was 20%. 37,38 Hypertension and diabetes are two sides of the same coin. In the present study, among individuals with diabetes, a new diagnosis of hypertension was established in 30% (54 subjects), whereas the percentage of known cases of hypertension and prehypertension among diabetic patients was 23.5% (43 subjects) and 35% (64 subjects), respectively.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of diabetes mellitus and its risk factors in urban communities of north Sudan: Population‐based study

Elmadhoun

Noor

Ibrahim

et al. 2016

Journal of Diabetes

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“…[ 9 , 10 ] In this regard, an accurate and reliable estimate of the prevalence of NAFLD in T2DM patients is important as it can help service providers to predict the number of subjects who may develop NAFLD, and hence implement intervention strategies to cope with the problem. [ 11 , 12 ]…”

Section: Introductionmentioning

confidence: 99%

Prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

et al. 2017

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Background:Nonalcoholic fatty liver disease (NAFLD) is emerging as a public health issue worldwide and is highly prevalent in patients with type 2 diabetes mellitus (T2DM). However, there was a great disparity across studies in the estimated prevalence of NAFLD in T2DM patients. This meta-analysis, therefore, aimed to estimate the pooled prevalence of NAFLD in T2DM patients.Methods:Electronic databases of PubMed, Web of Science, Embase, Chinese National Knowledge Infrastructure, and Wanfang were searched using MeSH terms to identify relevant studies. Eligibility assessment and data extraction were conducted independently by 2 investigators and a meta-analysis was performed to synthesize the data. Heterogeneity was evaluated using the Cochran Q test and quantified using the I2 statistic. Publication bias was assessed using both the Begg and Egger tests. Subgroup analyses were performed to identify the possible sources of heterogeneity.Results:Twenty-four studies involving 35,599 T2DM patients were included in this meta-analysis, of which 20,264 were identified with NAFLD. A high degree of heterogeneity (I2 = 99.0%, P < .001) was observed among the eligible studies, with the reported prevalence ranging from 29.6% to 87.1%. The pooled prevalence of NAFLD in T2DM patients, by a random-effects model, was 59.67% (95% confidence interval: 54.31–64.92%). Sensitivity was low and both the Begg test and Egger test showed low possibility of publication bias. Subgroup analyses indicated that the prevalence of NAFLD in T2DM patients differed by gender, obesity, hypertension, dyslipidemia, coronary heart disease, and chronic kidney disease.Conclusions:The high pooled prevalence of NAFLD in T2DM patients found in this study significantly underscores the need for early assessment of NAFLD and the importance of strengthening the management of NAFLD in T2DM patients.

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Prevalence of and predictive factors for nonalcoholic fatty liver disease in Sudanese individuals with type 2 diabetes: Is metabolic syndrome the culprit?

Cited by 36 publications

References 31 publications

Obesity among Sudanese adults with diabetes: a population-based survey

Obesity among Sudanese adults with diabetes: a population-based survey

Prevalence of diabetes mellitus and its risk factors in urban communities of north Sudan: Population‐based study

Prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

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