Prevalence of, and biochemical and anthropometric risk factors for, dyslipidemia in children and adolescents aged 7 to 18 years in China: A cross‐sectional study

He, Huijing; Pan, Li; Du, Jian; Liu, Feng; Jin, Yuming; Ma, Jingang; Wang, Li; Jia, Pengben; Hu, Zhiping; Shan, Guangliang

doi:10.1002/ajhb.23286

Cited by 17 publications

(18 citation statements)

References 23 publications

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“…A study on 2283 children and adolescents, aged 7-18 years, living in urban and rural areas of China revealed higher prevalence of elevated TC and LDL-C in girls than in boys. Furthermore, girls had higher mean values of HDL-C in comparison with boys [18]. Brazilian girls had also higher concentrations of TC and LDL-C compared with boys [19].…”

Section: Discussionmentioning

confidence: 99%

Reference values for lipid profile in Iranian children and adolescents: the CASPIAN-V study

et al. 2020

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Background: We aimed to develop the age-and sex-specific reference values for lipid profile of Iranian pediatric population. Methods: Fasting lipid profiles of 3843 participants, aged 7 to 18 years, were extracted from a surveillance survey on Iranian children and adolescents living in 30 provinces across the country. Results: The mean (SD) age of participants was 12.3(3.1) years, and 52.3% of them were boys. Significant differences were observed between genders comparing the levels of triglyceride (TG) (P = 0.04), total cholesterol (TC) (P = 0.02), low-density lipoprotein-cholesterol (LDL-C) (P = 0.01), and non-high-density lipoprotein cholesterol (non-HDL-C) (P = 0.03). In both genders, TG levels increased with age in the 75th and higher percentiles. Among boys, TC showed a decreasing trend at all percentiles and all age groups. In girls, TC levels increased with age at all percentiles except for the 75th and 90th percentiles. Among boys, the levels of LDL-C and HDL-C decreased with age in all percentiles. However, LDL-C and HDL-C concentrations increased up to the 50th percentile in girls and then decreased with age. The non-HDL-C level decreased in the 50th and higher percentiles among boys and in the 90th and 95th percentiles among girls. The TG/HDL-C ratio increased with age at all percentiles in boys. In girls, TG/HDL-C ratio increased with age in the 50th and higher percentiles. Conclusions: Based on the observed differences, it seems necessary to determine age-and sex-specific cut-off values for lipid parameters of children and adolescents in different populations.

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Section: Discussionmentioning

confidence: 99%

Reference values for lipid profile in Iranian children and adolescents: the CASPIAN-V study

et al. 2020

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“…Половозрастная динамика распространенности гиперхолестеринемии с максимальными уровнями холестерина в возрасте 8-9 лет, снижении к 13 годам у девочек и к 14-15 годам у мальчиков с последующим увеличением, вероятно, отражает возрастную динамику уровня общего холестерина у детей и подростков [2,14]. Для сравнения частота развития гиперхолестеринемии у детей 7-18 лет в Китае у девочек составляет 8,2%, у мальчиков -4,2%, что превышает полученные в настоящем исследовании средние показатели по 17 регионам Российской Федерации -4,1 и 3,0% соответственно [15].…”

Section: Discussionunclassified

Prevalence of risk factors of cardiovascular diseases in children and adolescents based on the data from health centers

Trunina

Буланова

Shchelykalina

et al. 2021

Ross. vestn. perinatol. pediatr.

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Цель исследования. Оценка распространенности избыточной массы тела, ожирения, повышенного артериального давления и гиперхолестеринемии у детей и подростков -посетителей центров здоровья. Характеристика детей и методы исследования. В одномоментном ретроспективном исследовании использованы данные длины и массы тела, артериального давления, уровня общего холестерина в свежей цельной капиллярной крови 70 001 ребенка (36 097 мальчиков) в возрасте 6-17 лет из 17 регионов Российской Федерации. Избыточную массу тела и ожирение определяли по диагностическим критериям Всемирной организации здравоохранения, по таблицам z-score индекса массы тела, учитывая пол и возраст. Гиперхолестеринемию диагностировали при уровне общего холестерина >5,2 ммоль/л, повышенное артериальное давление -при уровне систолического и/или диастолического артериального давления >95‰ кривой распределения артериального давления в популяции для соответствующего возраста, пола и роста. Результаты. Распространенность избыточной массы тела, ожирения, повышенного артериального давления и гиперхолестеринемии составила соответственно 18,2, 6,9, 5,2 и 3,0% у мальчиков и 15,9, 5,3, 4,8 и 4,1% у девочек. Частота выявления гиперхолестеринемии превышала стандартизованные показатели по 17 регионам Российской Федерации (3,5%) в Пермском крае (18,8%), Чувашской республике (6,9%) и Владимирской области (8,5%). Максимальная частота выявления избыточной массы тела и ожирения наблюдалась в Пермском крае -39,1% и 17,1%. Распространенность повышенного артериального давления превышала стандартизованные показатели по 17 регионам Российской Федерации (4,9%): в 2 раза -в Воронежской области (10,6%) и в 3 раза в регионе ХМАО-Югра (15,2%). Заключение. Полученные данные свидетельствуют о необходимости усиления мероприятий по профилактике сердечно-сосудистых заболеваний, изменению образа жизни и пищевых привычек в регионах России с высокой распространенностью изученных факторов риска развития сердечно-сосудистых осложнений начиная с детского и подросткового возраста.

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“…The present study is cross-sectional design and based on data collected in Hainan province, which is an island in southernmost China. The sampling method is the same with our previous studies [ 17 , 18 ]. Briefly, from Nov to Dec 2013, a multi-stage stratified clustering sampling method was used to enroll participants.…”

Section: Methodsmentioning

confidence: 99%

Body mass index was linked with multi-cardiometabolic abnormalities in Chinese children and adolescents: a community-based survey

Pan

et al. 2022

BMC Pediatr

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Background Evidence on how body mass index (BMI) influence cardiometabolic health remains sparse in Chinese children and adolescents, especially in south China. We aim to investigate the effect of overweight and/or obesity on high blood pressure (HBP), dyslipidemia, elevated serum uric acid (SUA) and their clustering among children and adolescents in an island in South China. Methods Using multi-stage cluster sampling method, 1577 children and adolescents aged 7–18 in Hainan province, south China, participated in the survey. The association between body mass index and cardiometabolic indexes were explored. Overweight and obesity were classified according to criteria of World Health Organization for children and adolescents aged 5 to 19. Restricted cubic spline models were used to examine the possible non-linear association between BMI and cardiometabolic profiles. Multivariable logistic regression models were fitted to examine the effect size of BMI on cardiometabolic disorders including HBP, elevated SUA and dyslipidemia. Comorbidity of at least two cardiometabolic abnormalities (HBP, dyslipidemia, elevated SUA) was defined as clustering of cardiometabolic risk factors. Results Comparing with normal weight and underweight subjects, overweight/obese youths had higher levels of BP, SUA, triglyceride, low-density lipoprotein but lower level of high-density lipoprotein. Overweight/obese youth had higher risk of dyslipidemia (OR:2.89, 95%CI: 1.65–5.06), HBP (OR:2.813, 95%CI: 1.20–6.59) and elevated SUA (OR: 2.493, 95%CI: 1.45–4.27), respectively, than their counterparts. The sex-, age-adjusted prevalence of abnormalities clustering was 32.61% (95% CI: 20.95% to 46.92%) in overweight/obesity group, much higher than in the under/normal weight group (8.85%, 95%CI: 7.44% to 10.48%). Conclusion Excess adiposity increased the risk of elevated serum uric acid, serum lipids, blood pressure and their clustering among children and adolescents in south China.

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Prevalence of, and biochemical and anthropometric risk factors for, dyslipidemia in children and adolescents aged 7 to 18 years in China: A cross‐sectional study

Cited by 17 publications

References 23 publications

Reference values for lipid profile in Iranian children and adolescents: the CASPIAN-V study

Reference values for lipid profile in Iranian children and adolescents: the CASPIAN-V study

Prevalence of risk factors of cardiovascular diseases in children and adolescents based on the data from health centers

Body mass index was linked with multi-cardiometabolic abnormalities in Chinese children and adolescents: a community-based survey

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