“…Genetic factors appear to have a key role in the association between schizophrenia and diabetes, since it has been reported that up to 50% of individuals with schizophrenia have a family history of type 2 diabetes, compared with just 4.6% of healthy adult controls (Dynes, 1969; Mukherjee et al 1989; Cheta et al , 1990; Lamberti et al , 2003; Shiloah et al , 2003). In one of the largest chart reviews ever conducted of schizophrenia, Lamberti et al (2003) found a family history of type 2 diabetes in 17% of the total cohort of 436 patients. Importantly, in the cohort of patients who had a positive family history of diabetes, the prevalence of diabetes mellitus was 33%.…”