Prevalence of abnormalities of electrocardiogram in old people.

Campbell, Allan; Caird, F. I.; Jackson, T F

doi:10.1136/hrt.36.10.1005

Cited by 72 publications

(25 citation statements)

References 12 publications

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“…A recent study in the United States, however, reported prevalences of 0.3% in people aged 65-69, 1.5% in those aged 70-79, and 3% in those aged over 80 30. The higher mortality from cerebrovascular and cardiovascular disease in the United Kingdom would suggest that atrial fibrillation may be more prevalent here, but British studies of prevalence have involved small numbers of elderly patients from unrepresentative populations 33 34 35 36 37 38. Best estimates are therefore based on the Australian and North American studies.…”

Section: Prevalence Of Atrial Fibrillationmentioning

confidence: 86%

How To Do It: Service provision and use of anticoagulants in atrial fibrillation

Sudlow

Rodgers

Kenny

et al. 1995

BMJ

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Several large trials have shown that the risk of stroke in patients with non-valvar atrial fibrillation is reduced by treatment with warfarin. Implementing this research evidence requires not only an understanding of the trials' results and of the changes that they imply for clinicians' treatment decisions but also an appreciation of the organisation, quantity, and quality of services required to support these changes. Understanding of these implications is crucial for developing services that allow changes in practice to produce reductions in stroke incidence while minimising the risks of treatment. This article considers the developments in service provision that will probably be required to support the changes in clinical practice suggested by the trials' results. These services will be provided largely by doctors, and their development has implications for doctors in both primary and secondary care.

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Section: Prevalence Of Atrial Fibrillationmentioning

confidence: 86%

How To Do It: Service provision and use of anticoagulants in atrial fibrillation

Sudlow

Rodgers

Kenny

et al. 1995

BMJ

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“…This is most likely caused by the increase of atrial fibrillation parallel to aging. [13][14][15] In contrast, large-artery atherosclerosis was the most prevalent etiology in middleaged patients (aged 45 to 70 years). Despite the frequent use of ancillary tests, the rate of unclassified stroke was still 23%, a proportion that is smaller than in some studies 2,16,17 but comparable to many other studies.…”

Section: Discussionmentioning

confidence: 97%

Risk Factors, Outcome, and Treatment in Subtypes of Ischemic Stroke: The German Stroke Data Bank

Grau¹,

Weimar²,

Buggle³

et al. 2001

Stroke

846

522

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on behalf of the German Stroke Data Bank CollaboratorsBackground and Purpose-Data on risk factors for etiologic subtypes of ischemic stroke are still scant. The aim of this study was to characterize stroke subtypes regarding risk factor profile, outcome, and current treatment strategies. Methods-We analyzed data from 5017 patients with acute ischemic stroke (42.4% women, aged 65.9Ϯ14.1 years) who were enrolled in a large multicenter hospital-based stroke data bank. Standardized data assessment and stroke subtype classification were used by all centers. Results-Sex and age distribution, major risk factors and comorbidities, recurrent stroke, treatment strategies, and outcome were all unevenly distributed among stroke subtypes (PϽ0.001, respectively). Cardioembolism, the most frequent etiology of stroke (25.6%), was particularly common in the elderly (those aged Ͼ70 years) and associated with an adverse outcome, a low rate of early stroke recurrence, and frequent use of thrombolytic therapy and intravenous anticoagulation. Large-artery atherosclerosis (20.9%), the most common cause of stroke in middle-aged patients (those aged 45 to 70 years), showed the highest male preponderance, highest rate of early stroke recurrence, and highest prevalence of previous transient ischemic attack, current smoking, and daily alcohol consumption among all subtypes. The highest prevalence of hypertension, diabetes mellitus, hypercholesterolemia, and obesity was found in small-vessel disease (20.5%), which, in turn, was associated with the lowest stroke severity and mortality. Conclusions-Our results foster the concept of ischemic stroke as a polyetiologic disease with marked differences between subtypes regarding risk factors and outcome. Therefore, studies involving risk factors of ischemic stroke should differentiate between etiologic stroke subtypes. (Stroke. 2001;32:2559-2566.)

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“…However, although recognised as a risk factor for stroke, atrial fibrillation has received little attention as an aetiological factor in cerebrovascular dementia and is not mentioned as a risk factor in studies using an ischaemia index to differentiate cerebrovascular from senile dementia (Hachinski et al, 1975;Loeb and Gandolfo, 1983). In recent studies of acute stroke patients (Lowe et al, 1983;Lovett et al, 1981;Greenland et al, 1981) the prevalence of atrial fibrillation is reported between 9 and 25% which is much higher than that in population studies such as that by Campbell et al (1974) where atrial fibrillation was found in 2% of those aged 65-74 and 5% of those aged 75 or more. In our patients, the incidence was even higher, perhaps a reflection ofthe great age ofour study group, and the fact that most had multiple areas ofcerebral infarction.…”

Section: Discussionmentioning

confidence: 99%

Cerebrovascular disease in dementia: the importance of atrial fibrillation

Ratcliffe

Wilcock

1985

Postgraduate Medical Journal

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Summary The relationship between cardiovascular disease and cerebral infarction was analysed in a prospectively assessed post mortem series of 48 demented patients. Hypertension was rare in this group of patients whose mean age was 82.7 y. Atrial fibrillation was the most important underlying cardiac abnormality. It is suggested that atrial fibrillation is more important than hypertension in the aetiology of cerebral infarction in the very aged and that this may be relevant to the pathogenesis of cerebrovascular dementia.

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Prevalence of abnormalities of electrocardiogram in old people.

Abstract: The electrocardiograms of 2254

Cited by 72 publications

References 12 publications

How To Do It: Service provision and use of anticoagulants in atrial fibrillation

How To Do It: Service provision and use of anticoagulants in atrial fibrillation

Risk Factors, Outcome, and Treatment in Subtypes of Ischemic Stroke: The German Stroke Data Bank

Cerebrovascular disease in dementia: the importance of atrial fibrillation

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