Prevalence of 25-Hydroxyvitamin D Deficiency in the Acute Inpatient Rehabilitation Population and Its Effect on Function

Pellicane, Anthony J.; Wysocki, Nicole M.; Mallinson, Trudy; Schnitzer, Thomas J.

doi:10.1016/j.apmr.2010.12.028

Cited by 16 publications

(14 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…42 Two studies on the relationship between vitamin D levels and functional outcome measures among patients in a rehabilitation setting did not document a positive correlation between the two. 35,43,44 …”

Section: Primary Endpoint: Mortalitymentioning

confidence: 98%

Screening and Treatment of Vitamin D Deficiency on Hospital Admission: Is There a Benefit for Medical Inpatients?

Grädel

Merker

Müeller

et al. 2016

The American Journal of Medicine

View full text Add to dashboard Cite

show abstract

Section: Primary Endpoint: Mortalitymentioning

confidence: 98%

Screening and Treatment of Vitamin D Deficiency on Hospital Admission: Is There a Benefit for Medical Inpatients?

Grädel

Merker

Müeller

et al. 2016

The American Journal of Medicine

View full text Add to dashboard Cite

show abstract

“…Higher levels of vitamin D have been shown to correlate with greater bone mineral density (BMD), lower rates of osteoporotic fractures, and improved neuromuscular function [8,9]. In addition, recent studies have shown a relationship between gene polymorphisms of vitamin-D receptors (VDRs) and osteoporosis [10,11].…”

Section: Introductionmentioning

confidence: 98%

Vitamin-D measurement in patients with adolescent idiopathic scoliosis

Balioğlu

Aydin

Kargın

et al. 2017

Journal of Pediatric Orthopaedics B

View full text Add to dashboard Cite

Our retrospective study compared vitamin-D levels in 229 patients with adolescent idiopathic scoliosis (AIS) and 389 age-matched controls, and evaluated the correlation between vitamin-D levels and sex, Cobb's angle, and serum levels of calcium (Ca), phosphorus, and alkaline phosphatase in the AIS group. Vitamin-D levels were lower in the AIS group, with no sex-specific effects, indicative of a possible vitamin-D resistance in AIS. Vitamin-D levels correlated positively with Ca levels and negatively with Cobb's angle, indicative of a possible role of vitamin D in the etiopathogenesis of AIS. Patients with AIS should be monitored for vitamin-D deficiency/insufficiency.

show abstract

“…The ability of patients in rehabilitation to go outdoors and obtain vitamin D from sun exposure is often limited due to decreased functional mobility and hospitalization . In looking toward decreasing these risks, previous studies demonstrated that vitamin D supplementation reduced the rate of vitamin D deficiency in patients undergoing rehabiliation . Despite the evidence of widespread VDD and VDI in rehabilitation patients and the effectiveness of vitamin D supplementation in increasing serum levels, there is limited literature regarding effective interventions to increase screening and supplementation in the acute inpatient rehabilitation setting.…”

Section: Introductionmentioning

confidence: 99%

“…Inadequate levels of vitamin D in patients undergoing inpatient rehabilitation have been confirmed in previous studies. VDD has been found in 34%-93% of patients with spinal cord injuries, [6][7][8] 25% of patients with traumatic brain injuries, 7 72%-94% of patients with orthopedic injuries, [9][10][11] and 70%-94% of patients undergoing general rehabilitation with mixed diagnoses. 10,12 In addition, 83% of inpatients in subacute rehabilitation were found to have VDD.…”

Section: Introductionmentioning

confidence: 99%

Intervention for Increasing Vitamin D Supplementation in a Deficient Rehabilitation Population: Outcomes of a Quality Improvement Initiative

Krull

Abramoff

Jerome

et al. 2019

PM&R

View full text Add to dashboard Cite

Background Vitamin D deficiency (VDD) is highly prevalent and increases the risk of osteoporosis, falls, and fractures. Patients in acute inpatient rehabilitation have several risk factors for VDD, the adverse effects of which may hinder long‐term functional gain. Objective To evaluate the prevalence of and risk factors for VDD in patients admitted to acute inpatient rehabilitation and to evaluate the efficacy of a standardized vitamin D screening and supplementation protocol. Design Prospective cohort study as part of a quality improvement initiative. Setting An academic, freestanding acute inpatient rehabilitation hospital. Participants Patients consecutively admitted over a 4‐month period between November 2014 and February 2015 (n=128 pre‐intervention and n=129 post‐intervention). Intervention Universal screening of vitamin D level on admission followed by utilization of a standard supplementation protocol. Main Outcome Measures Vitamin D insufficiency (VDI) and VDD prevalence along with screening, and supplementation rates. Results Preintervention, 10.2% of patients were screened for VDD, with 23.1% VDI and 46.2% VDD. Postintervention, 89.9% were screened, with 31.9% VDI and 47.4% VDD. 6.3% of all patients were supplemented on vitamin D preintervention compared to 53.5% postintervention. In multivariate analyses, the odds of VDD was significantly associated with African American race (OR 7.30, 95% CI, 1.56‐34.20, P = .12) and age younger than 65 (OR 13.62 95% CI, 2.51‐73.83, P = .002). Diagnoses in the “other neurologic” category were associated with decreased odds of VDD (OR 0.01, 95% CI, 0.001‐0.193, P = .002). Conclusions Given the high prevalence of VDD in an acute inpatient rehabilitation hospital, a routine screening and standardized supplementation protocol may improve quality of care. Level of Evidence III

show abstract

Prevalence of 25-Hydroxyvitamin D Deficiency in the Acute Inpatient Rehabilitation Population and Its Effect on Function

Cited by 16 publications

References 39 publications

Screening and Treatment of Vitamin D Deficiency on Hospital Admission: Is There a Benefit for Medical Inpatients?

Screening and Treatment of Vitamin D Deficiency on Hospital Admission: Is There a Benefit for Medical Inpatients?

Vitamin-D measurement in patients with adolescent idiopathic scoliosis

Intervention for Increasing Vitamin D Supplementation in a Deficient Rehabilitation Population: Outcomes of a Quality Improvement Initiative

Contact Info

Product

Resources

About