Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates 11Reprints are not available.

Kannel, William B.; Wolf, Philip A.; Benjamin, Emelia J.; Levy, Daniel

doi:10.1016/s0002-9149(98)00583-9

Cited by 1,836 publications

(1,291 citation statements)

References 41 publications

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“…1,2 Both hypertension and ECG LVH have been shown to predict the development of atrial fibrillation, which is itself a major independent risk for stroke. 27 In our study, information on the presence of atrial fibrillation was not available at baseline or during follow-up.…”

Section: Discussionmentioning

confidence: 96%

Left ventricular hypertrophy determined by Sokolow–Lyon criteria: a different predictor in women than in men?

et al. 2006

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The clinical usefulness of the Sokolow-Lyon voltage criteria in the assessment of electrocardiographic left ventricular hypertrophy (ECG LVH) is addressed. We prospectively studied 3338 women and 3330 men referred with hypertension, with an average follow-up of 11.2 years. The voltage amplitude sum SV1 þ max (RV5 or RV6) was calculated and ECG LVH was defined as a sum X3.5 mV. We adjusted survival for age, treatment status before presentation and a previous myocardial infarction or cerebrovascular accident. The risk of stroke, coronary heart disease (CHD) and cardiovascular disease (CVD) mortality increased significantly for each quantitative 0.1 mV increase in baseline electrocardiogram (ECG) voltage, in women within the range of 1.6-3.9% and in men 1.4-3.0%. After further adjustments for race, body mass index, smoking and systolic blood pressure, increasing voltage independently predicted CVD mortality in both men and women. In women, both increasing voltage and the presence of left ventricular hypertrophy (LVH) were predictors of stroke mortality, whereas in men this risk was attenuated. In men, the adjusted association between increasing voltage and CHD mortality tended to be stronger than in women. The use of different thresholds for the two genders made little difference. For stroke and CHD mortality, the population attributable fractions associated with LVH were 15.2 and 5.4% in women and 12.8 and 8.5% in men, respectively. In conclusion, the greater the baseline ECG voltage sum, the greater the associated CVD mortality risk. Women tended to have a high risk of stroke mortality owing to LVH despite adjustments.

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Section: Discussionmentioning

confidence: 96%

Left ventricular hypertrophy determined by Sokolow–Lyon criteria: a different predictor in women than in men?

et al. 2006

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“…39 Second, AF increases risk of stroke by an average of 5-fold. 40 AF-related strokes are more severe than those not related to AF. 41 Third, AF increases mortality, and has been linked to an increased risk of sudden death.…”

Section: Section 2: Definitions Mechanisms and Rationale For Af Ablmentioning

confidence: 97%

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Calkins,

Kuck,

Cappato

et al. 2012

Heart Rhythm

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“…2,3,21 -26 Furthermore, the 2 diseases share a number of risk factors (eg, increasing age, obesity, diabetes, heart failure, and hypertension), and the 2 diseases often coexist. 1,20,27 …”

Section: Vascular Disease and Stroke Risk In Atrial Fibrillationmentioning

confidence: 99%

Atrial Fibrillation and Vascular Disease—A Bad Combination

Olesen

Gislason

Torp‐Pedersen

et al. 2012

Clinical Cardiology

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This article provides an overview of (i) the risk of stroke associated with vascular disease (acute coronary syndromes and peripheral artery disease) in patients with atrial fibrillation, (ii) the frequent coexistence of vascular disease in patients with atrial fibrillation and, (iii) the cardiovascular risk associated with the coexisting of the two diseases. The literature on this topic is relatively sparse, and we discuss results from both clinical trials and observational studies.There is a clear indication of an increased stroke risk associated with vascular disease in patients with atrial fibrillation. Indeed, patients with atrial fibrillation often had coexisting vascular disease (around 18%), and the combination of the two diseases substantially increases the risk of future cardiovascular events. The increased risk associated with peripheral artery disease in atrial fibrillation is even more pronounced.Patients with atrial fibrillation and stable vascular disease should be treated with oral anticoagulation only, although when these patients present with acute coronary syndrome and/or undergo coronary stenting, concomitant treatment with antiplatelet drugs is indicated. To guide antithrombotic management in patients with atrial fibrillation, several stroke and bleeding risk prediction schemes have been developed. Clin. Cardiol. 2012 DOI: 10.1002/clc.20955Dr. Olesen received an honorarium through an educational grant from Sanofi Aventis for time and expertise spent writing this article. Dr Lip has served as a consultant for Bayer, Astellas, Merck, AstraZeneca, Sanofi, BMS/Pfizer, Biotronik, Portola and Boehringer Ingelheim and has been on the speakers bureau for Bayer, BMS/Pfizer, Boehringer Ingelheim, and Sanofi‐Aventis. Drs. Gislason and Torp‐Pedersen disclose no conflicts of interest.

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Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates 11Reprints are not available.

Cited by 1,836 publications

References 41 publications

Left ventricular hypertrophy determined by Sokolow–Lyon criteria: a different predictor in women than in men?

Left ventricular hypertrophy determined by Sokolow–Lyon criteria: a different predictor in women than in men?

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Atrial Fibrillation and Vascular Disease—A Bad Combination

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