Prevalence, incidence and outcomes of diabetes in Ontario First Nations children: a longitudinal population-based cohort study

Shulman, Rayzel; Slater, Morgan; Khan, Shahriar; Jones, Carmen; Walker, Jennifer; Jacklin, Kristen; Green, Michael E.; Frymire, Eliot; Shah, Baiju R.

doi:10.9778/cmajo.20190226

Cited by 15 publications

(10 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The type 2 diabetes prevalence in the latter study was highest in the oldest age group (12-17 years), among Black participants, and among female participants, which mirrors the findings from the current study. A Canadian study reported an increase in the prevalence of type 2 diabetes among First Nations youths younger than 20 years from 1.7 per 1000 youths in 1995 to 5.7 per 1000 youths in 2015, an absolute increase of 4.0 per 1000 youths, or 235%, over 20 years . In these 3 studies, the type 2 diabetes prevalence estimates were higher than the current study, but the prevalence approximately doubled over the observation period in each study.…”

Section: Discussioncontrasting

confidence: 83%

Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017

Lawrence

Divers

Isom

et al. 2021

JAMA

332

203

View full text Add to dashboard Cite

IMPORTANCEChanges in the prevalence of youth-onset diabetes have previously been observed.OBJECTIVE To estimate changes in prevalence of type 1 and type 2 diabetes in youths in the US from 2001 to 2017. DESIGN, SETTING, AND PARTICIPANTSIn this cross-sectional observational study, individuals younger than 20 years with physician-diagnosed diabetes were enumerated from 6 areas in the US (4 geographic areas, 1 health plan, and select American Indian reservations) for 2001, 2009, and 2017. EXPOSURES Calendar year. MAIN OUTCOMES AND MEASURES Estimated prevalence of physician-diagnosed type 1 and type 2 diabetes overall and by race and ethnicity, age, and sex. RESULTS Among youths 19 years or younger, 4958 of 3.35 million had type 1 diabetes in 2001, 6672 of 3.46 million had type 1 diabetes in 2009, and 7759 of 3.61 million had type 1 diabetes in 2017; among those aged 10 to 19 years, 588 of 1.73 million had type 2 diabetes in 2001, 814 of 1.85 million had type 2 diabetes in 2009, and 1230 of 1.85 million had type 2 diabetes in 2017. The estimated type 1 diabetes prevalence per 1000 youths for those 19 years or younger increased significantly from 1.48 (95% CI, 1.44-1.52) in 2001 to 1.93 (95% CI, 1.88-1.98) in 2009 to 2.15 (95% CI, 2.10-2.20) in 2017, an absolute increase of 0.67 per 1000 youths (95%, CI, 0.64-0.70) and a 45.1% (95% CI, 40.0%-50.4%) relative increase over 16 years. The greatest absolute increases were observed among non-Hispanic White (0.93 per 1000 youths [95% CI, 0.88-0.98]) and non-Hispanic Black (0.89 per 1000 youths [95% CI, 0.88-0.98]) youths. The estimated type 2 diabetes prevalence per 1000 youths aged 10 to 19 years increased significantly from 0.34 (95% CI, 0.31-0.37) in 2001 to 0.46 (95% CI, 0.43-0.49) in 2009 to 0.67 (95% CI, 0.63-0.70) in 2017, an absolute increase of 0.32 per 1000 youths (95% CI, 0.30-0.35) and a 95.3% (95% CI, 77.0%-115.4%) relative increase over 16 years. The greatest absolute increases were observed among non-Hispanic Black (0.85 per 1000 youths [95% CI, 0.74-0.97]) and Hispanic (0.57 per 1000 youths [95% CI, 0.51-0.64]) youths. CONCLUSIONS AND RELEVANCEIn 6 areas of the US from 2001 to 2017, the estimated prevalence of diabetes among children and adolescents increased for both type 1 and type 2 diabetes.

show abstract

Section: Discussioncontrasting

confidence: 83%

Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017

Lawrence

Divers

Isom

et al. 2021

JAMA

332

203

View full text Add to dashboard Cite

show abstract

“…Once a rare disease in youth, T2D is becoming more common and accounts for a significant proportion of youth onset diabetes in certain at‐risk populations. Worldwide incidence and prevalence of T2D in children and adolescents vary substantially among countries, age categories and ethnic groups 129–134 . The incidence and prevalence of T2D are highest among youth from a minority race/ethnicity, 99 likely because of many factors, including genetics, metabolic characteristics, cultural/environmental influences, and quality of and access to health care 135,136 …”

Section: Epidemiology Of T2dmentioning

confidence: 99%

ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and classification of diabetes in children and adolescents

et al. 2022

View full text Add to dashboard Cite

“…Thus, reducing the duration and number of hospitalizations will be effective in reducing the cost of treatment of DFU. Patients with DFU may need to stay in the hospital for a longer duration due to uncontrolled hyperglycemia, long-term wound care, late-healing wound infections, debridement, amputations, and emerging complications; (12) these factors contributed to increasing the cost. The average cost was also found to increase as the Wagner grade increased.…”

Section: Discussionmentioning

confidence: 99%

Hospitalisation Cost of Diabetic Patients with Foot Ulcers: A Retrospective Descriptive Analysis from Turkey

Açar¹,

Acar²,

Sayıner³

et al. 2021

Turk J Endocrinol Metab

View full text Add to dashboard Cite

Objective: With the increase in the prevalence of diabetes and associated complications, most of the healthcare expenditure is due to treatments of diabetes complications. This study evaluated the determinants affecting the total treatment cost in hospitalized patients with diabetic foot ulcers (DFU), an important complication of diabetes. Material and Methods: Factors affecting cost in 300 cases of hospitalization due to DFU were analyzed retrospectively. Hospital invoices were examined, and incurred cost of each patient was calculated in Turkish lira and then converted into US dollars at the exchange rate on the date of hospitalization, considering the number of days of hospitalization. Results: Among the 300 included patients, the ratio of male/female participants was 1.94. The mean age of the patients was 62.6±11 years. Hemoglobin A1c mean was determined as 9.5±2.4%. The average hospitalization time was 17.8±12.9 days. When the average cost was analyzed according to Wagner phases, the average cost increased as the stage of the disease.The factor that most affected the cost was hospitalization cost (p=0.001, r=3.24). Diagnostic imaging tests affected the total cost the most (p=0.001, r=2.52) after hospitalization. Conclusion: The cost of hospitalization was the most important factor affecting the total cost in the analysis of DFU. Therefore, taking precautions before the advancement of ulcer stage and treatment at an early stage is expected to reduce the treatment cost.In addition, reducing the duration of hospital stay will be effective in reducing the cost of DFU treatment.

show abstract

Prevalence, incidence and outcomes of diabetes in Ontario First Nations children: a longitudinal population-based cohort study

Cited by 15 publications

References 30 publications

Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017

Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017

ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and classification of diabetes in children and adolescents

Hospitalisation Cost of Diabetic Patients with Foot Ulcers: A Retrospective Descriptive Analysis from Turkey

Contact Info

Product

Resources

About