Prévalence, gravité et facteurs prédictifs de la dysplasie bronchopulmonaire dans une cohorte ultramarine de grands prématurés

Richard, M.; Ramful, Duksha; Robillard, P.-Y.; Mussard, Corinne; Loumouamou, Y.; Ogier, M.; Tasset, Chantal; Nguyen, Alex; Alessandri, Jean‐Luc; Sampériz, Sylvain; Gérardin, Patrick

doi:10.1016/j.arcped.2013.05.002

Cited by 2 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results may also illustrate the higher fatality rate in the most immature VPT infants and a selective survival bias, mortality and BPD risks being competitive and better survival observed in low-risk infants. In support of our previous results, these new findings suggest that better respiratory and nutritional strategies starting from the delivery room and continued in the neonatal care unit are locally warranted [25, 26].…”

Section: Discussionsupporting

confidence: 84%

Mortality and severe morbidity of very preterm infants: comparison of two French cohort studies

Godeluck¹,

Gérardin²,

Lenclume³

et al. 2019

BMC Pediatr

View full text Add to dashboard Cite

Background In Reunion Island, a French overseas department, the burden of preterm birth and perinatal mortality exceed those observed in mainland France, despite similar access to standard perinatal care. The purpose of the study was to compare the outcome of two cohorts of NICU-admitted very preterm infants born between 24 and 31 weeks of gestation (WG): the registry-based OGP (Observatoire de la Grande Prématurité, Reunion Island, 2008–2013) cohort, and the nationwide EPIPAGE-2 (mainland France, 2011) observational cohort. Methods The primary outcome was adverse neonatal outcomes defined as a composite indicator of in-hospital mortality or any of three following severe morbidities: bronchopulmonary dysplasia (BPD), necrotising enterocolitis, or severe neurological injury (periventricular leukomalacia or grade III-IV intraventricular haemorrhages). Logistic regression modelling adjusting for confounders was performed. Results A total of 1272 very preterm infants from the Reunionese OGP cohort and 3669 peers from the mainland EPIPAGE-2 cohort were compared. Adverse neonatal outcomes were more likely observed in the OGP cohort (32.6% versus 26.6%, p < 0.001), as result of both increased in-hospital mortality across all gestational age strata and increased BPD among the survivors of the 29–31 WG stratum. After adjusting for gestational age, gender and multiple perinatal factors, the risk of adverse neonatal outcomes was higher in the OGP cohort than in the EPIPAGE-2 cohort across all gestational age strata. Conclusions Despite similar guidelines for standard perinatal care, very preterm infants born in Reunion Island have a higher risk for death or severe morbidity compared with those born in mainland France.

show abstract

Section: Discussionsupporting

confidence: 84%

Mortality and severe morbidity of very preterm infants: comparison of two French cohort studies

Godeluck¹,

Gérardin²,

Lenclume³

et al. 2019

BMC Pediatr

View full text Add to dashboard Cite

show abstract

“…In a limited number of prospective studies focused on growth and developmental outcomes, the incidence of BPD did not differ between those who received "early and/or higher AA intake" and those who received conventional timing and doses of AA 49 , 50 , 51) . Two studies have shown an association between the risk of BPD and delayed or lower quantity of enteral (but not parenteral) nutrition 52 , 53) . Because fluid intake is closely linked to calorie intake in the early neonatal period, it may confound the association between early nutrition and BPD.…”

Section: Early Nutrition and Neonatal Morbiditiesmentioning

confidence: 99%

Nutritional strategy of early amino acid administration in very low birth weight infants

Lee

2015

Korean J Pediatr

View full text Add to dashboard Cite

Relative to a fetus of the same gestational age, very low birth weight (VLBW) infants are more likely to be underfed and to undergo growth restriction during their early hospital stay. The current trend towards "early and aggressive" nutritional strategies in VLBW infants aims to overcome the early nutritional deficiency and thereby boost postnatal catch-up growth, simultaneously improving long-term neurodevelopmental outcomes. Although the minimum starting amino acid (AA) dose to prevent negative nitrogen balance is well established, the upper limit and the rate of increase of early AA doses are controversial. Most randomized controlled trials show that early and high-dose (target, 3.5 to 4.9 g/kg/day) AA regimens, with or without high nonprotein calories, do not improve long-term growth and neurodevelopment. High-dose AA supplementation may lead to early metabolic disturbances and excessive or disproportionate plasma AA levels, particularly in infants of very low gestational age. Further large studies are needed to clarify the optimal strategy for early administration of parenteral AA doses in VLBW infants.

show abstract

Prévalence, gravité et facteurs prédictifs de la dysplasie bronchopulmonaire dans une cohorte ultramarine de grands prématurés

Cited by 2 publications

References 26 publications

Mortality and severe morbidity of very preterm infants: comparison of two French cohort studies

Mortality and severe morbidity of very preterm infants: comparison of two French cohort studies

Nutritional strategy of early amino acid administration in very low birth weight infants

Contact Info

Product

Resources

About