Prevalence, etiology and risk factors of anemia in patients with newly diagnosed cancer

Kenar, Gökçe; Köksoy, Elif Berna; Ürün, Yüksel; Utkan, Güngör

doi:10.1007/s00520-020-05336-w

Cited by 20 publications

(16 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In newly diagnosed cancer patients; Kenar et al evaluated that metastatic disease, de ciencies such as iron, B12 and folate, gastrointestinal cancer, and a history of previous tumor surgery are possible risk factors (7). Direct in ltration of the bone marrow by cancer cells, reduction of RBC production by causing iron sequestration of cancer cells and shortening its life, chronic blood loss from tumoral areas, deterioration in oral intake and deterioration in the coagulation system can be evaluated as the causes of anemia seen in patients with cancer.…”

Section: Discussionmentioning

confidence: 99%

Prognostic Effects of Red Blood Cell Transfusion in Lung Cancer Patients Receiving Chemotherapy

Ayçiçek

Küçük

et al. 2022

Preprint

View full text Add to dashboard Cite

Introduction: The effects of blood transfusion on the prognosis in lung cancer patients are not yet clearly known, but it is frequently applied in clinical practice.Aim: The aim of this study is to evaluate the relationship between blood transfusion frequency and disease prognosis in lung cancer patients receiving chemotherapy. Results: A total of 405 patients were included in the study. Blood transfusion was performed in 96 (23.7%) of the patients. While the progression rate was 67.4% in the infected group, this rate was 47% in the non-infected group (p<0.001), similarly, the median number of progressions was statistically significantly higher in the infected group (p=0.001). While the rate of infection development was 68.8% in the transfused group, this rate was statistically significantly lower at 35.3% in the non-transfused group (p<0.001). It was determined that 21 (38.2%) of the patients who resulted in exitus were transfused with 3.1 ± 3.0 units to the mean, and an average of 2.81 ± 2.24 units of blood was transfused to 75 (21.4%) of the 350 (86.4%) surviving patients. While there is a statistically significant difference in terms of whether or not blood transfusion is performed in survived and non-survived patients (p=0.011), no significant difference was found in the average blood transfusion amounts per person (p= 0.640).Conclusion: It was determined that red blood cell transfusions due to anemia during the disease in lung cancer patients who were treated with chemotherapy, adversely affected survival and disease progression.

show abstract

Section: Discussionmentioning

confidence: 99%

Prognostic Effects of Red Blood Cell Transfusion in Lung Cancer Patients Receiving Chemotherapy

Ayçiçek

Küçük

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Varios autores coinciden en que las pruebas de laboratorio son importantes como base para los estudios, en cuanto al diagnóstico, al seguimiento y al pronóstico de los participantes. 5,6,[9][10][11] Además, la anemia en el adulto mayor tiene una relación con la demencia, así lo mencionan en su estudio Chang et al,¹ donde evidenció que las personas con anemia tenían un mayor riesgo de desarrollar demencia a comparación de las personas sin anemia. Por su parte, Andro et al⁷ apoyaron estas evidencias con su estudio, en el que sí existe una asociación entre la anemia y el deterioro cognitivo global, a su vez, entre la anemia y las funciones ejecutivas, además de la incidencia de demencia.…”

Section: Discussionunclassified

Factores de riesgo asociados a la anemia ferropénica en adultos mayores

Orcon

Ruiz²

2022

RMB

View full text Add to dashboard Cite

Objetivo: Realizar una revisión sistemática de diversas publicaciones científicas acerca de los factores de riesgo asociados a la anemia ferropénica en adultos mayores. Métodos: La revisión se realizó a través de la búsqueda electrónica de diversos artículos científicos relacionados con el tema. Se utilizó la pregunta PEO: ¿cuál es la asociación entre los factores de riesgo y la anemia ferropénica en adultos mayores? La fuente de búsqueda fue PubMed. Se seleccionaron los artículos publicados desde el 1 de enero de 2016 hasta el 2021. Resultados: De los 223 artículos encontrados, se descartaron 212 por no cumplir con los criterios de inclusión y exclusión, por lo tanto, quedaron 11 artículos para esta revisión. Conclusión: Diversos factores de riesgos intrínsecos y extrínsecos se asocian a la adquisición de anemia ferropénica o por deficiencia de hierro en pacientes adultos mayores.

show abstract

“…This regulation might be another key mechanism of vitamin D–mediated innate immune function, complementary to its reported effects on antibacterial proteins [ 215 , 216 ] and autophagy [ 217 , 218 ]. Although common to many chronic diseases [ 219 ], systemic inflammation and related anemia are likely to be particularly important in cancer patients, indicating disease severity [ 220 ] and correlating with the risk of developing multiple pathological complications, therapy responsiveness and the duration of disease-free survival [ 221 ].…”

Section: Evidence Of Cra Modulation By Lifestyle Interventions In mentioning

confidence: 99%

Cancer Related Anemia: An Integrated Multitarget Approach and Lifestyle Interventions

et al. 2021

View full text Add to dashboard Cite

Cancer is often accompanied by worsening of the patient’s iron profile, and the resulting anemia could be a factor that negatively impacts antineoplastic treatment efficacy and patient survival. The first line of therapy is usually based on oral or intravenous iron supplementation; however, many patients remain anemic and do not respond. The key might lie in the pathogenesis of the anemia itself. Cancer-related anemia (CRA) is characterized by a decreased circulating serum iron concentration and transferrin saturation despite ample iron stores, pointing to a more complex problem related to iron homeostatic regulation and additional factors such as chronic inflammatory status. This review explores our current understanding of iron homeostasis in cancer, shedding light on the modulatory role of hepcidin in intestinal iron absorption, iron recycling, mobilization from liver deposits, and inducible regulators by infections and inflammation. The underlying relationship between CRA and systemic low-grade inflammation will be discussed, and an integrated multitarget approach based on nutrition and exercise to improve iron utilization by reducing low-grade inflammation, modulating the immune response, and supporting antioxidant mechanisms will also be proposed. Indeed, a Mediterranean-based diet, nutritional supplements and exercise are suggested as potential individualized strategies and as a complementary approach to conventional CRA therapy.

show abstract

Prevalence, etiology and risk factors of anemia in patients with newly diagnosed cancer

Cited by 20 publications

References 33 publications

Prognostic Effects of Red Blood Cell Transfusion in Lung Cancer Patients Receiving Chemotherapy

Prognostic Effects of Red Blood Cell Transfusion in Lung Cancer Patients Receiving Chemotherapy

Factores de riesgo asociados a la anemia ferropénica en adultos mayores

Cancer Related Anemia: An Integrated Multitarget Approach and Lifestyle Interventions

Contact Info

Product

Resources

About