Prevalence, drug resistance, and genotypic diversity of the RDRio subfamily of Mycobacterium tuberculosis in Ecuador: a retrospective analysis for years 2012–2016
Bernardo Castro-Rodriguez,
Greta Franco-Sotomayor,
Jose Manuel Benitez-Medina
et al.
Abstract:IntroductionA major sublineage within the Mycobacterium tuberculosis (MTB) LAM family characterized by a new in-frame fusion gene Rv3346c/55c was discovered in Rio de Janeiro (Brazil) in 2007, called RDRio, associated to drug resistance. The few studies about prevalence of MTB RDRio strains in Latin America reported values ranging from 3% in Chile to 69.8% in Venezuela, although no information is available for countries like Ecuador.MethodsA total of 814 MTB isolates from years 2012 to 2016 were screened by mu… Show more
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