“…Additionally, 42% of psychiatric patients compared with 5% of normal controls reported gastroesophageal refluxrelated symptoms [7]. Furthermore, according to several studies of psychological comorbidities in GERD patients, anxiety, depression, and somatization are significantly more common as compared with normal controls [8,9]. There is evidence that increased severity of GERD, as determined by frequency and duration of symptoms, is more likely to be associated with psychological distress [10].…”