Prevalence, associations, and adequacy of treatment of major depression in patients with cancer: a cross-sectional analysis of routinely collected clinical data

Walker, Jane; Hansen, Christian Holm; Martín, Paul; Symeonides, Stefan N.; Ramessur, Ravi; Murray, Gordon; Sharpe, Michael

doi:10.1016/s2215-0366(14)70313-x

Cited by 326 publications

(310 citation statements)

References 26 publications

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“…Walker et al screened depression in 21151 cancer patients (6). Major depression was frequent in lung cancer, gynecological cancer, breast, colorectal and genitourinary cancer.…”

Section: Discussionmentioning

confidence: 99%

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The depression and related factors among cancer patients and their family caregivers in Turkish Population

Ustaalioglu¹,

Acar²

2017

Acta Oncol Tur.

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ÖZET GİRİŞ ve AMAÇ:Kanserli hastalar arasında depresyon oranı %29 olarak bildirilmiştir. Depresyon varlığı, hem hastayı, hem de hastaya bakmakla yükümlü aile üyelerini olumsuz yönde etkiler. Bu çalışmada, kemoterapi alan hastalar ve onlara bakmakla yükümlü yakınlarında depresyon varlığını, sosyo-demografik faktörler ve günlük aktivitelerin depresyonla ilişkisini değerlendirdik. YÖNTEM ve GEREÇLER: Toplam 302 kanser hastası ve 302 yakınını inceledik. Depresyonu Beck Depresyon Envanteri (BDE) ile değerlendirdik. Depresyon için sınır değeri 17 olarak kabul ettik ve depresyonla ilişkili sosyodemografik özellikleri analiz ettik. BULGULAR: Depresyon skorları hasta grupta yakınlarına göre daha yüksekti (12,5 ile 8). Hastalığı yeterince bilmeme, günlük sosyal aktivitelerde kısıtlılık, hem hasta hem yakınlarında depresyon varlığı ile ilişkiliydi. Korrelasyon analizi ile hasta yakınlarında, eğitim seviyesi, iş durumu, aylık gelir depresyonla ters orantılı iken, hastanın hastalığını bilme, depresyonla ilişkiliydi. Hastalar için ise, semptom varlığı, aile ziyaretleri, depresyonu predikte eden faktörlerdi. Bununla beraber, hasta yakınları için aile ziyaretleri ve aylık gelir depresyonu predikte eden bağımsız faktörler olarak bulundu. TARTIŞMA ve SONUÇ: Hem hasta, hem de yakınlarında kültürel farklılıklar bazında depresyonu predikte eden faktörleri tesbit etmek, tedaviye yardımcı olacağı gibi hayat kalitelerinin de artmasına yardımcı olacaktır. Anahtar Kelimeler: depresyon, kanser hastası, bakım veren aile üyesi, Beck depresyon envanteri, depresyon skoru ABSTRACT INTRODUCTION: Depression has been reported as 29% in frequency among cancer patients. The presence of depression negatively effect both the patients and their family member who provide the care the patients. In the present study we evaluated the presence of depression in cancer patients receiving chemotherapy and their caregivers and the relatioship between socio-demographical factors and daily social activities with depression. METHODS: Totally,302 cancer patients and 302 family caregiver of them were evaluated. Depression was analyzed with Beck Depression Invantery(BDI). The cut-off value for depression was 17 and the sociodemograpfical factors related with depression were analyzed. RESULTS: Depression scores was higher in patients then their caregivers(12.5vs8). Insufficent information about disease and rare social activities were related with depression for both cancer patients and their caregivers. By correlation analysis, educational level, occupational status and income were inversely related with depression but the knowing the the diagnosis of the patients by caregiver was positively related with depression. The presence of symptom and family visit were independent predicting factor for depression of patients. On the other hand family visit and income were important independent factors for caregiver depression. DISCUSSION AND CONCLUSION: Findings of the predicting factor of depression for both patients and their caregiver according to culturel diversity may h...

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“…Walker et al screened depression in 21151 cancer patients (6). Major depression was frequent in lung cancer, gynecological cancer, breast, colorectal and genitourinary cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Major depression was frequent in lung cancer, gynecological cancer, breast, colorectal and genitourinary cancer. Betweeen these groups younger age and low social deprivation score were associated with more depression (6). And also oropharyngeal cancer, pancreatic, breast and lung cancer were reported more associated with depression (17).…”

Section: Discussionmentioning

confidence: 99%

The depression and related factors among cancer patients and their family caregivers in Turkish Population

Ustaalioglu¹,

Acar²

2017

Acta Oncol Tur.

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“…1 Colorectal cancer is frequently associated with anxiety (2.91%) and depression (54.37%) disorders, [2][3][4] both considered leading specific causes of years lived with disability (YLDs) in 2010. 5 Anxiety and depression strongly and independently affect health-related quality of life.…”

Section: Introductionmentioning

confidence: 99%

Association of Anger Expression-Out with NK Cell Counts in Colorectal Cancer Patients

2018

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RESUMOIntrodução: Existe crescente evidência da relação entre fatores psicológicos e progressão do cancro colorrectal. Vários mecanismos têm sido propostos porém o mais promissor baseia-se na modulação da resposta imune anti-tumoral pelos fatores psicológicos, particularmente através das células natural killer. Esta investigação teve como objetivo o estudo da relação entre as células natural killer e a ansiedade, a depressão e o estado, traço e expressão da raiva num grupo de 54 doentes pré-cirúrgicos com cancro colorrectal.

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“…The mental health of cancer patients has significant effects on their overall quality of life (e.g., Skarstein, Aass, Fosså, Skovlund, & Dahl, 2000), responses to treatment (e.g., DiMatteo, Lepper, & Croghan, 2000), and survival times (e.g., Falagas et al, 2007). While estimates vary, of the most common mental health problems, the prevalence of depression and anxiety in people with cancer has been conservatively estimated to be around twice that of the general population (Hinz et al, 2010;Walker et al, 2014). Common mental health problems, such as depression and anxiety, can be experienced as a consequence of cancer treatment regimens (e.g., Spiegel, 1997), as well as affecting how well cancer patients respond to them (DiMatteo et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

The effect of disgust-related side-effects on symptoms of depression and anxiety in people treated for cancer: a moderated mediation model

et al. 2016

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Prevalence, associations, and adequacy of treatment of major depression in patients with cancer: a cross-sectional analysis of routinely collected clinical data

Abstract: Cancer Research UK and Chief Scientist Office of the Scottish Government.

Cited by 326 publications

References 26 publications

The depression and related factors among cancer patients and their family caregivers in Turkish Population

The depression and related factors among cancer patients and their family caregivers in Turkish Population

Association of Anger Expression-Out with NK Cell Counts in Colorectal Cancer Patients

The effect of disgust-related side-effects on symptoms of depression and anxiety in people treated for cancer: a moderated mediation model

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