Prevalence and trends of urolithiasis among adults

Abufaraj, Mohammad; Karmi, Joud Al; Yang, Lin

doi:10.1097/mou.0000000000000994

Cited by 26 publications

(18 citation statements)

References 45 publications

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“…Urolithiasis is a prevalent disease with an increasing tendency across the world [ 4 , 5 ]. The prevalence of urolithiasis was estimated to be approximately 12% in North America and 5–9% in Europe [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Association between Urolithiasis and History Proton Pump Inhibitor Medication: A Nested Case-Control Study

Kim

Yoo

Bang

et al. 2022

JCM

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A few retrospective studies have suggested the risk of urolithiasis associated with the use of proton pump inhibitors (PPIs). The current research intended to estimate the risk of urolithiasis according to previous PPI use. A nested case-control study was conducted using the National Health Insurance Service-National Health Screening Cohort in Korea. A total of 28,962 patients with urolithiasis and 115,848 control participants were selected. The previous prescription history of PPI with days of PPI prescription was collected. To calculate the odds ratios (OR) of past, current, and days of PPI use for urolithiasis, logistic regression models were used. Subgroup analyses were conducted. The urolithiasis group demonstrated a higher rate of current PPI users than the control group (60.9% vs. 43.7%). The current PPI users indicated 2.49 times higher odds for urolithiasis than no PPI users (95% confidence intervals [CI] = 2.33–2.66). A longer duration of PPI use was associated with greater odds for urolithiasis (adjusted OR = 1.65 (95% CI = 1.54–1.77) < 1.97 (95% CI = 1.84–2.11) < 2.32 (95% CI = 2.14–2.49) for 1–19 days, 30–364 days, and 365 or more days of PPI prescription). All subgroup analyses described a consistently positive association of previous PPI use with urolithiasis. Prior PPI use was related to a higher risk of urolithiasis. The relationship between previous PPI use and urolithiasis demonstrated a dose-response association.

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Section: Introductionmentioning

confidence: 99%

Association between Urolithiasis and History Proton Pump Inhibitor Medication: A Nested Case-Control Study

Kim

Yoo

Bang

et al. 2022

JCM

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“…In recent years, there has been a dramatic increase in its incidence, particularly in developed countries. The rising prevalence of kidney stones substantially burdens healthcare systems worldwide 8–10 . In the United States alone, the total expenditure for kidney stone treatment was approximately $2.1 billion in 2000, which has since risen to an estimated $3.79 billion.…”

Section: Introductionmentioning

confidence: 99%

Understanding formation processes of calcareous nephrolithiasis in renal interstitium and tubule lumen

Dong,

Zhou,

et al. 2024

J Cellular Molecular Medi

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Kidney stone, one of the oldest known diseases, has plagued humans for centuries, consistently imposing a heavy burden on patients and healthcare systems worldwide due to their high incidence and recurrence rates. Advancements in endoscopy, imaging, genetics, molecular biology and bioinformatics have led to a deeper and more comprehensive understanding of the mechanism behind nephrolithiasis. Kidney stone formation is a complex, multi‐step and long‐term process involving the transformation of stone‐forming salts from free ions into asymptomatic or symptomatic stones influenced by physical, chemical and biological factors. Among the various types of kidney stones observed in clinical practice, calcareous nephrolithiasis is currently the most common and exhibits the most intricate formation mechanism. Extensive research suggests that calcareous nephrolithiasis primarily originates from interstitial subepithelial calcified plaques and/or calcified blockages in the openings of collecting ducts. These calcified plaques and blockages eventually come into contact with urine in the renal pelvis, serving as a nidus for crystal formation and subsequent stone growth. Both pathways of stone formation share similar mechanisms, such as the drive of abnormal urine composition, involvement of oxidative stress and inflammation, and an imbalance of stone inhibitors and promoters. However, they also possess unique characteristics. Hence, this review aims to provide detailed description and present recent discoveries regarding the formation processes of calcareous nephrolithiasis from two distinct birthplaces: renal interstitium and tubule lumen.

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“…Urolithiasis affects 5–15% of the world’s population, and the recurrence rate can be as high as 50% within 5–10 years of stone removal and 75% within the next 20 years. Residual fragments (RF) are the most important risk factor for stone recurrence or new stone growth [1]. Traditionally, RF less than 4 mm in diameter are defined as a clinically insignificant RF that can be excreted spontaneously, while RF greater than 4 mm are defined as significant residual fragments that require aggressive treatment [2].…”

Section: Introductionmentioning

confidence: 99%

Physical Techniques to Remove Residual Stone Fragments in the Urinary System

Qiu,

Zhang,

Zhang

et al. 2023

Urol Int

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Background: Although significant progress has been made in treatment techniques for renal and ureteral calculi, residual fragments (RF) persisting long after treatment pose a serious threat to patients’ health. A variety of novel physical techniques and extraction devices are currently being developed to promote the removal of RF from the urinary system, and a series of in vivo experiments have demonstrated their safety and efficacy. Summary: External physical vibration lithecbole, magnetic extraction, biocompatible stone adhesive-based methods, and ultrasonic propulsion technologies are examples of innovative therapies that can promote the clearance of RF and improve the stone-free rate. In conclusion, the physical treatment of these RF needs to be optimized and improved. They are a promising technique for improving the efficiency of endovascular urology, and further in vivo studies are needed to confirm their safety and efficacy. Key Messages: We have summarized the literature on removal of RF by physical methods in recent years, especially the new progress.

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Prevalence and trends of urolithiasis among adults

Cited by 26 publications

References 45 publications

Association between Urolithiasis and History Proton Pump Inhibitor Medication: A Nested Case-Control Study

Association between Urolithiasis and History Proton Pump Inhibitor Medication: A Nested Case-Control Study

Understanding formation processes of calcareous nephrolithiasis in renal interstitium and tubule lumen

Physical Techniques to Remove Residual Stone Fragments in the Urinary System

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