“…A growing body of literature documents trends in increasingly problematic PO use and street-level availability in Canada: data indicate that rates of NPOU are rising in general adult and student populations (Boak, Hamilton, Adlaf, & Mann, 2013; Health Canada, 2013) and NPOU is emergent among key marginalized populations, including street-drug users (Popova, Patra, Mohapatra, Fischer, & Rehm, 2009), First Nations/Aboriginal people (Dell et al, 2012; Katt et al, 2012), and correctional populations (Johnson, MacDonald, Cheverie, Myrick, & Fischer, 2012). Local Vancouver studies of youth and adults who use drugs have seen a marked rise in the availability of POs, particularly oxycodone and hydrocodone, in street-level drug markets between 2006 and 2010, despite the high and stable availability of other illicit drugs (Nosyk et al, 2012), and injection and non-injection PO use has surpassed heroin use among some drug-using populations in Canada (Fischer et al, 2006; Leclerc, Morissette, & Roy, 2010).…”