“…12,13 Several authors have noted symptoms after PAO that may be attributable to postoperative femoroacetabular impingement or acetabular labral tears. [13][14][15][16][17][18][19] The prevalence of intra-articular pathology at the time of PAO is substantial. 13,19,20 It stands to reason that many of these symptoms may be a cause of failure or revision surgery after osteotomy.…”
“…12,13 Several authors have noted symptoms after PAO that may be attributable to postoperative femoroacetabular impingement or acetabular labral tears. [13][14][15][16][17][18][19] The prevalence of intra-articular pathology at the time of PAO is substantial. 13,19,20 It stands to reason that many of these symptoms may be a cause of failure or revision surgery after osteotomy.…”
“…Labral pathologic changes were noted in 20.8%, but no specific data were provided in terms of morphologic characteristics and pattern of injury. 12 Fujii et al 10 In a larger single-center series of 73 hips treated by PAO-hip arthroscopy, Ross et al 22 reported the presence of labral tears or degeneration in 63 hips (86.3%), and the labrum was classified as hypertrophic in 46 hips (63%). The current study includes patients from that series but clearly represents a much larger, multicenter cohort from which to draw more generalizable conclusions.…”
Section: Discussionmentioning
confidence: 99%
“…17 Through several retrospective case series, symptomatic acetabular dysplasia has also been associated with a hypertrophied labrum, labral tears, and chondral injuries. 9,10,12,16,18 The presence of a hypertrophied labrum, in particular, has been suggested by some to be a consistent diagnostic finding in acetabular dysplasia. 16 While periacetabular osteotomy may be successful to reorient the acetabulum and improve anterolateral coverage of the femoral head, adjunctive procedures are often performed to address coexisting intra-articular pathologic changes.…”
mentioning
confidence: 96%
“…3,8,17 The current literature in this area primarily consists of level 4 retrospective evidence derived from singleinstitution case series, which may not be entirely generalizable to other patient populations. 9,10,12,16,18 Therefore, the need exists to more accurately describe labral morphologic characteristics, ideally in a large, prospective cohort from several regionally distinct centers.…”
Labral pathologic changes are common in patients with symptomatic acetabular dysplasia. Labral hypertrophy, however, is not a universal finding, particularly in hips with mild dysplasia, and therefore should not be considered a reliable diagnostic criterion for instability.
“…The transtrochanteric surgical dislocation approach, devised by Ganz et al, is now standard for nondestructive, extensive, open intra-articular hip preservation surgery around the world [40][41][42] . Newer approaches to the hip joint allow surgery to be performed directly on articular cartilage, but biological obstacles to chondral repair remain a strong incentive to correct mechanical problems before irreversible chondral damage occurs 2,13,14,43 . Experience provided by the surgical dislocation approach has facilitated the development of less invasive arthroscopic surgery to address a subset of intra-articular hip disorders that can be safely accessed through percutaneous portals 38,44 .…”
Section: Thirty Years Of Experience In Joint-preservation Surgerymentioning
Osteoarthritis is a leading cause of disability. The traditional focus on late-stage osteoarthritis has not yielded effective disease-modifying treatments. Consequently, current clinical care focuses on palliation until joint replacement is indicated. A symposium format was used to examine emerging strategies that support the transformation of the clinical approach to osteoarthritis from palliation to prevention. Central to this discussion are concepts for diagnosis and treatment of pre-osteoarthritis, meaning joint conditions that increase the risk of accelerated development of osteoarthritis. The presentation of translational and clinical research on three common orthopaedic conditions-anterior cruciate ligament tear, intra-articular fracture, and hip dysplasia-were used to illustrate these ideas. New information regarding the use of novel quantitative magnetic resonance imaging (MRI) in the form of ultrashort echo time enhanced T2* (UTE-T2*) mapping to evaluate the potential for articular cartilage to heal subsurface damage in a mechanically sound environment was presented. These data indicate that improved diagnostics can both identify cartilage at risk and evaluate the effectiveness of early treatment strategies. With use of a new mouse model for intra-articular fracture, it was shown that inflammation correlated to fracture severity and that super-healer mice avoided early posttraumatic osteoarthritis in part through an enhanced ability to dampen inflammation. These findings suggest that there is a role for acute and sustained anti-inflammatory treatment in the prevention of osteoarthritis. For long-term treatment, contemporary gene-therapy approaches may offer an effective means for sustained intra-articular delivery of anti-inflammatory and other bioactive agents to restore joint homeostasis. To illustrate the potential of early treatment to prevent or delay the onset of disabling osteoarthritis, the positive clinical effects on articular cartilage and in long-term clinical follow-up after operative correction of structural abnormalities about the hip highlight the role for targeting mechanical factors in delaying the onset of osteoarthritis. Given that orthopaedic surgeons treat the full spectrum of joint problems, ranging from joint trauma to preosteoarthritic conditions and end-stage osteoarthritis, an awareness of the paradigm shift toward the prevention of osteoarthritis is critical to the promotion of improved clinical care and participation in clinical research involving new treatment strategies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.