Prevalence and risk factors of overactive bladder in Chinese children: A population‐based study

Abstract

Aims: To investigate the prevalence of overactive bladder (OAB) and assess its risk factors in 5-to 14-year-old Chinese children. Methods: A cross-sectional study of OAB prevalence was performed by distributing 11 800 anonymous self-administered questionnaires to parents in five provinces of mainland China from July to October 2018. The questionnaires included questions on sociodemographics, history of urinary tract infection (UTI), lower urinary tract symptoms (LUTS), family history of LUTS, bowel symptoms, and details about the elimination communication (EC) start time.OAB was defined as urgency and increased the daytime frequency with or without urinary incontinence. Results: A total of 10 133 questionnaires qualified for statistical analysis. The overall prevalence of OAB was 9.01% and decreased with age, from 12.40% at 5 years to 4.55% at 14 years (χ 2 trend = 88.899; P < .001). The proportion of dry OAB increased with age, whereas the proportion of wet OAB decreased. A lateonset of EC was associated with a high OAB prevalence (χ 2 trend = 39.802; P < .001). Children with obesity, a history of UTI, nocturnal enuresis (NE), a family history of LUTS, constipation, and fecal incontinence had a higher prevalence of OAB than did normal children (P < .05).Conclusion: Obesity, a history of UTI, NE, a family history of LUTS, and bowel symptoms are risk factors associated with OAB. Starting EC before 12 months of age might help reduce the prevalence of OAB in children. K E Y W O R D S children, elimination communication, overactive bladder, prevalence

Association Between Obesity and Lower Urinary Tract Symptoms Among Children and Adolescents: A Community-Based Study

“…A former study by the authors demonstrated that childhood obesity was an independent risk factor for pediatric OAB symptoms (OR 1.97; 95% CI: 1.14-3.40) (14). Similarly, a large scale study in China which was conducted by Xing et al (19) and evaluated 10,133 anonymous questionnaires, disclosed that children with obesity, a history of urinary tract infection, nocturnal enuresis, a family history of LUTSs, constipation, and fecal incontinence, had a significantly higher prevalence of OAB compare with normal children (p < 0.05). Fraga et al (20) conducted a cross-sectional study which included 423 children and adolescents aged 5-17 years.…”

Is there a unique symptom in lower urinary tract dysfunction in children?

“…We found a strong correlation of constipation with DV but there are studies in the literature showing the association of LUTS and constipation and also OAB with constipation. According to Dong Xing et al, children with constipation have a higher prevalence of OAB than do normal children, with bowel symptoms being a risk factor related to OAB in children 14 . Results of studies on LUTS show that, by treating constipation alone, LUTS can be improved, for instance, Ji Hyun Kim et al showed that OAB symptoms improved with constipation treatment 15 .…”

Long-term functional and psychosocial outcome in adolescents and young adults treated for lower urinary tract dysfunction in childhood

“…Lower urinary tract dysfunction(LUTD) is prevalent in up to 31% of 6-8 year-old children and approximately 5% of adolescents. 1,2 In young adults, the prevalence varies greatly between 2-53% depending on the selected population, type of urinary tract symptoms, severity and measurements used. 3,4 Several studies suggest a link between adult LUTD and childhood urinary incontinence (UI).…”