Prevalence and Risk Factors of Gallbladder Polypoid Lesions in a Healthy Population

Choi, Yun-Sang; Hyuk, Jae; Seo, Suk; Lee, Seung Eun; Oh, Hyoung Chul; Min, Yun Joo; Kang, Hyun

doi:10.3349/ymj.2016.57.6.1370

Cited by 47 publications

(30 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prevalence of GB polyps ranges from 1.3% to 9.5%, with geographical differences [ 3 - 6 ]. A Korean data demonstrated that the prevalence of GB polyps in Korea ranges from 2.2% to 9.9%, which is similar to other studies [ 7 , 8 ]. The guidelines for the diagnosis and treatment of GB polyps have remained unchanged for a while.…”

Section: Introductionsupporting

confidence: 86%

Gallbladder polyps: evolving approach to the diagnosis and management

Kim

2021

Yeungnam Univ J Med

View full text Add to dashboard Cite

Gallbladder (GB) polyps are defined as mucosal projection of the GB wall into the lumen [1]. Recently, with the easy availability of ultrasonography (US) and the increasing awareness of physical checkup, the detection of GB polypoid lesion is steadily on the rise [2]. Most GB polyps are incidentally found and asymptomatic. Although benign lesions are overwhelming, some can be transformed into malignant. Polyps more than 1 cm in size and adenomatous polyps are of clinical importance due to the risk of cancerous change. The prevalence of GB polyps ranges from 1.3% to 9.5%, with geographical differences [3-6]. A Korean data demonstrated that the prevalence of GB polyps in Korea ranges from 2.2% to 9.9%, which is similar to other studies [7,8]. The guidelines for the diagnosis and treatment of GB polyps have remained unchanged for a while. In this review, the diagnosis, classification, natural history, and algorithm for the management of GB polyps will be described. Gallbladder (GB) polyp is a mucosal projection into the GB lumen. With increasing health awareness, GB polyps are frequently found using ultrasonography during health screening. The prevalence of GB polyps ranges between 1.3% and 9.5%. Most patients are asymptomatic and have benign characteristics. Of the nonneoplastic polyps, cholesterol polyps are most common, accounting for 60%-70% of lesions. However, a few polyps have malignant potential. Currently, the guidelines recommend laparoscopic cholecystectomy for polyps larger than 1 cm in diameter due to their malignant potential. The treatment algorithm can be influenced by the size, shape, and numbers of polyps, old age (>50 years), the presence of primary sclerosing cholangitis, and gallstones. This review summarizes the commonly recognized concepts on GB polyps from diagnosis to an algorithm of treatment.

show abstract

Section: Introductionsupporting

confidence: 86%

Gallbladder polyps: evolving approach to the diagnosis and management

Kim

2021

Yeungnam Univ J Med

View full text Add to dashboard Cite

show abstract

“…Gallbladder polypoid lesions are also called gallbladder (GB) polyps, which is a general term for a collection of lesions that protrude from the gallbladder mucosal wall into the gallbladder lumen, as a morphologic concept. The incidence of GB polyps in adults is approximately 5% in Western countries (1,2), but the rate is much higher in Eastern countries (7.4%–9.9%) (3,4). There are more than 20 pathological types of GB polyps, which are generally classified as neoplastic (such as adenomatous polyps or adenocarcinoma) and non-neoplastic (such as cholesterol polyps, inflammatory polyps, or gallbladder adenomyosis) lesions in the clinic (5).…”

Section: Introductionmentioning

confidence: 99%

Dual-energy CT to differentiate gallbladder polyps: cholesterol versus adenomatous

et al. 2020

View full text Add to dashboard Cite

Background Dual-energy computed tomography (DE-CT) scans were acquired to identify cholesterol and adenomatous gallbladder (GB) polyps, which have not been well evaluated before surgery. Purpose To evaluate the DE-CT findings of GB polyps 1.0–2.0 cm in size and differentiate between cholesterol and adenomatous polyps. Material and Methods Forty-six patients with GB polyps were surgically treated from December 2017 to December 2019 and divided into two groups according to their postoperative pathologic results: a cholesterol group with 26 patients and an adenomatous group with 20 patients. All of these patients underwent DE-CT imaging with tube voltages of 80 kVp and 140 kVp within two weeks before surgery. Mean attenuation values were measured for every GB polyp at 80/140 kVp and at 40/140 keV. The mean attenuation value changes between 140 kVp and 80 kVp (MAVC140–80 kVp) and mean attenuation value changes between 100 keV and 40 keV (MAVC100–40 keV) were calculated. Results The CT image parameters of all 46 patients with GB polyps were analyzed. There were significant differences in MAVC140–80 kVp and MAVC100–40 keV between cholesterol and adenomatous polyps ( P <0.05); these values were positive for cholesterol polyps and negative for adenomatous polyps. Conclusion The unique energy spectrum information provided by DE-CT scans is helpful in differentiating between cholesterol and adenomatous polyps 1.0–2.0 cm in size.

show abstract

“…The reported risk factors for GBP are male sex [36789], old age [45], and chronic hepatitis B viral infection [589]. Previous studies have also identified metabolic syndrome factors (including obesity, high body mass index [BMI], dyslipidemia, and glucose intolerance) as risk factors for GBPs [2345689101112].…”

Section: Introductionmentioning

confidence: 99%

Ovo-lactovegetarian diet as a possible protective factor against gallbladder polyps in Taiwan: A cross-sectional study

Liu

Chen

2019

Tzu Chi Med J

View full text Add to dashboard Cite

Objective:Gallbladder polyps (GBPs) are an increasingly common incidental finding and 3% to 8% of GBPs become malignant. A poor prognosis is expected in patients with gallbladder cancer. No studies have considered the relationship between diet and the development of GBPs in the Taiwanese population. The objective of this study was to investigate whether a vegetarian diet protects against GBP development.Materials and Methods:This cross-sectional study included 11,717 individuals who received a health checkup at Taipei Tzu Chi Hospital (New Taipei City, Taiwan) between October 2011 and October 2016. All individuals completed questionnaires that collected data about their characteristics, dietary patterns, and lifestyle. Physical examinations were conducted, and blood chemistry tests were performed. The presence of GBPs was determined using ultrasonography. We subsequently evaluated the association between diet and GBP prevalence using multivariate analysis.Results:The prevalence of GBPs for the entire group was 8.3%. GBPs were significantly less common in the vegetarian groups (vegans 9.0%, ovo-lacto vegetarians 7.5%, and semi-vegetarians 7.2%) compared with the omnivore group (9.6%) (P = 0.002). Step-wise logistic regression revealed that an ovo-lacto vegetarian diet was a possible protective factor (odds ratio = 0.83, P = 0.015).Conclusions:The study findings showed a strong negative association between an ovo-lacto vegetarian diet and GBP occurrence.

show abstract

Prevalence and Risk Factors of Gallbladder Polypoid Lesions in a Healthy Population

Cited by 47 publications

References 21 publications

Gallbladder polyps: evolving approach to the diagnosis and management

Gallbladder polyps: evolving approach to the diagnosis and management

Dual-energy CT to differentiate gallbladder polyps: cholesterol versus adenomatous

Ovo-lactovegetarian diet as a possible protective factor against gallbladder polyps in Taiwan: A cross-sectional study

Contact Info

Product

Resources

About