“…Thus, it is diffi cult to conclude whether actual prevalence of OSA in the LABS-2 cohort is closer to 53%, as determined in the entire cohort from a combination of assessment methods, or 81%, as determined in the subsample who had past-year AHI available. It is interesting to note that this prevalence of OSA in the subsample with past-year AHI is consistent with several small single-center studies that determined OSA status via PSG (prevalence range: 72-98%), [3][4][5][6][7][8] while the prevalence in the group without a known past-year AHI is in line with a large cohort study in which OSA prevalence (41%) was determined with a set of screening questions. 9 Self-reported PAP compliance (i.e., use among those with OSA), which was similar between participants with and without past-year AHI (83.0% and 81.2%, respectively), was higher than objectively determined compliance reported in the general population, which is between 40% and 60% one year after starting PAP.…”