Prevalence and risk factors for diabetic retinopathy in Asian Indians with young onset Type 1 and Type 2 Diabetes

Rajalakshmi, Ramachandran; Amutha, Anandakumar; Ranjani, Harish; Ali, Mohammed K.; Unnikrishnan, Ranjit; Anjana, Ranjit Mohan; Narayan, K.M. Venkat; Mohan, Viswanathan

doi:10.1016/j.jdiacomp.2013.12.008

Cited by 75 publications

(69 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[4][5][6][7][8]10,19,21,22,24,28,30,34,[38][39][40][42][43][44][47][48][49][50][51][52][53] 69 This is consistent with other genome-wide association studies in Caucasian and Mexican-American patients. 70,71 As the relationship between genetic polymorphisms and diabetic retinopathy is still a new and emerging field, some studies have demonstrated new associations between single nucleotide polymorphisms, but these studies have not yet been replicable.…”

supporting

confidence: 88%

“…10,23 This emphasises the importance of optimal glycaemic control in diabetic patients in order to prevent diabetic retinopathy. In contrast, this association was not seen in youngonset type 1 DM, 24 a difference that may be attributed to the role of hyperglycaemic memory. 25 The ACCORD study 26 compared the effects of intensive glycaemic treatment with target HbA1c of <6.0% compared with standard treatment with target HbA1c of 7.0% to 7.9%.…”

Section: Glycaemic Controlmentioning

confidence: 63%

“…6,8,16,21,24,30 In fact, one study reported that patients with diabetic retinopathy had longer duration of diabetes, double than those without retinopathy (25 ± 10 vs 12 ± 8 years; P<0.0001). 30 This was corroborated by Zhang et al 7 in a large-scale study which found that patients with diabetic retinopathy had a longer duration of diabetes (15.0 ± 1.6 years vs 7.3 ± 0.8 years; P<0.001).…”

Section: Duration Of Diabetesmentioning

confidence: 99%

“…Both greater waist-hip ratio and waist circumference are positively associated with diabetic retinopathy. 6,22,24 The OR of diabetic retinopathy is 1.28 per 5-cm increase in waist circumference (OR=1.28; 95% CI, 1.05-1.56; P=0.014). 24 The association between BMI and diabetic retinopathy has been variable among studies.…”

Section: Obesitymentioning

confidence: 99%

“…6,22,24 The OR of diabetic retinopathy is 1.28 per 5-cm increase in waist circumference (OR=1.28; 95% CI, 1.05-1.56; P=0.014). 24 The association between BMI and diabetic retinopathy has been variable among studies. A study looking specifically at patients with type 1 DM found that obesity with a BMI of >30 kg/m 2 was the predominant risk factor for diabetic retinopathy, even when controlling for other risk factors such as HbA1c and the use of cardioprotective drugs.…”

Section: Obesitymentioning

confidence: 99%

See 4 more Smart Citations

Associations between diabetic retinopathy and systemic risk factors

Wat¹,

Wong²,

Wong³

2016

Hong Kong Med J

View full text Add to dashboard Cite

Introduction: Diabetes mellitus is a systemic disease with complications that include sight-threatening diabetic retinopathy. It is essential to understand the risk factors of diabetic retinopathy before effective prevention can be implemented. The aim of this review was to examine the association between diabetic retinopathy and systemic risk factors.Methods: A PubMed literature search was performed up to May 2016 to identify articles reporting associations between diabetic retinopathy and systemic risk factors; only publications written in English were included. Relevant articles were selected and analysed. Results:Patients with diabetic retinopathy were more likely to have poor glycaemic control as reflected by a higher glycated haemoglobin, longer duration of diabetes, and use of insulin therapy for treatment. For other systemic risk factors, hypertension was positively associated with prevalence and progression of diabetic retinopathy. No clear association between obesity, hyperlipidaemia, gender, or smoking with diabetic retinopathy has been established as Associations between diabetic retinopathy and systemic risk factors IntroductionDiabetic retinopathy is the leading cause of blindness in adults living in developed countries. 1 Almost all patients with type 1 diabetes mellitus (DM) and more than 60% of patients with type 2 DM will develop some degree of retinopathy after a 20-year history of diabetes.2 It has also been well established that DM increases the risk of cardiovascular disease. 3Cheng et al 4 found that the prevalence of diabetic retinopathy associated with one, two, three, or four cardiometabolic risk factors was 16.0%, 17.6%, 21.3%, or 25.1%, respectively (P=0.001). This implies a relationship between systemic health conditions and diabetic retinopathy. In order to help identify and to prevent progression of this ophthalmic complication of diabetes, a better understanding of its association with systemic risk factors is necessary. MethodsA PubMed literature search was conducted up to May 2016 using the following key words: "diabetic retinopathy", "prevalence", "epidemiology", "systemic associations", "risk factors", "diabetic Hong Kong Med J 2016;22:589-99

show abstract

supporting

confidence: 88%

Section: Glycaemic Controlmentioning

confidence: 63%

Section: Duration Of Diabetesmentioning

confidence: 99%

Section: Obesitymentioning

confidence: 99%

Section: Obesitymentioning

confidence: 99%

See 3 more Smart Citations

Associations between diabetic retinopathy and systemic risk factors

Wat¹,

Wong²,

Wong³

2016

Hong Kong Med J

View full text Add to dashboard Cite

show abstract

Association of Type 1 Diabetes vs Type 2 Diabetes Diagnosed During Childhood and Adolescence With Complications During Teenage Years and Young Adulthood

Dabelea

Stafford

Mayer‐Davis

et al. 2017

JAMA

533

456

View full text Add to dashboard Cite

Role of the Funder/Sponsor: Drs Linder (NIH), Imperatore, and Saydah (CDC) were participating members of the study steering committee and the writing group for this manuscript because of the cooperative funding agreements. They were involved in the design of the study but not the conduct of the study; they were not involved in the collection, management, and analysis of the data, but were involved in interpretation of the data; they were involved in the preparation, review, and approval of the manuscript and the decision to submit the manuscript for publication.

show abstract

Longitudinal changes in fasting plasma glucose are associated with risk of cancer mortality: A Chinese cohort study

Yang

et al. 2021

Cancer Medicine

View full text Add to dashboard Cite

show abstract

Prevalence and risk factors for diabetic retinopathy in Asian Indians with young onset Type 1 and Type 2 Diabetes

Cited by 75 publications

References 39 publications

Associations between diabetic retinopathy and systemic risk factors

Associations between diabetic retinopathy and systemic risk factors

Association of Type 1 Diabetes vs Type 2 Diabetes Diagnosed During Childhood and Adolescence With Complications During Teenage Years and Young Adulthood

Longitudinal changes in fasting plasma glucose are associated with risk of cancer mortality: A Chinese cohort study

Contact Info

Product

Resources

About