Prevalence and risk factors for dilatation of sinus of Valsalva in boys with X-linked Alport syndrome
M. E. Aksenova,
K. M. Tutelman,
L. L. Anikalchuk
Abstract:X-linked Alport syndrome is multisystem disease caused by mutation in COL4A5. Aortic dilatation described in X-linked Alport syndrome is considered a specific manifestation of the disease.Purpose. To define prevalence and risk factors for aortic dilatation in boys with X-linked Alport syndrome.Methods. Retrospective cross-section single center study included boys with X-linked Alport syndrome (n=67, age 10.2±4.6), comparison group consisted of boys with congenital urinary tract abnormalities (n=20, age12.2±4.8… Show more
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