Prevalence and risk factors for gastroesophageal reflux disease in an impoverished minority population

Friedenberg, Frank K.; Rai, Jitha; Vanar, Vishwas; Bongiorno, Charles A.; Nelson, Deborah B.; Parepally, Mayur; Poonia, Arashdeep; Sharma, Amol; Gohel, Shaun; Richter, Joel E.

doi:10.1016/j.orcp.2010.06.001

Cited by 16 publications

(34 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is why we did not control for age in our analysis. We adjusted for physical activity [49], diabetes [50,51], BMI [52,53,54,55,56], and diet-related behaviors [57] in our analyses, as earlier studies have introduced these variables as contributing factors to GERD and FD.…”

Section: Discussionmentioning

confidence: 99%

Smoking Status and Prevalence of Upper Gastrointestinal Disorders

Esmaillzadeh¹,

Keshteli

Tabesh³

et al. 2014

Digestion

View full text Add to dashboard Cite

Background: Lifestyle and environmental factors affecting upper gastrointestinal (GI) disorders are different in developing countries than those in developed nations. Objective: This study aimed to examine the association between smoking status and upper GI disorders among a large group of the Iranian adult population. Methods: This cross-sectional study was conducted among 1,933 adult men in Isfahan, Iran. Smoking status was assessed by a self-administered questionnaire. Required information on GI health was collected through the use of the validated ROME III questionnaire. Individuals who reported having heartburn sometimes, often, or always in the last 3 months were considered as having epidemiologic gastroesophageal reflux disease (GERD), and those who reported having heartburn often or always were considered as having clinical GERD. Subjects who reported having functional dyspepsia (FD) symptoms (based on the ROME III criteria) sometimes, often, or always in the last 3 months were considered as having epidemiologic FD, and those who reported having these disorders often or always were considered as having clinical FD. Results: Smoking was prevalent among 7.8% of the study population. FD and GERD was prevalent among 12.6% (n = 244) and 22.3% (n = 432), respectively. Smoking was not associated with GERD by either the epidemiologic or clinical definition. Although the association between smoking and FD (epidemiologic definition) was not statistically significant, smokers had an 83% higher risk of suffering from clinical FD compared with nonsmokers after taking potential confounders into account [odds ratio (OR) = 1.83, 95% CI: 1.12-3.00; p = 0.01]. Smokers had a 57% higher risk for epidemiologic postprandial fullness (OR = 1.57, 95% CI: 1.05-2.33; p = 0.02) and a 92% higher risk for clinical epigastric pain compared with nonsmokers (OR = 1.92, 95% CI: 1.02-3.62; p = 0.04). We found no significant association between smoking and severity of upper GI disorders. Conclusion: This large population-based study indicated that smoking was not associated with GERD and epidemiologic FD. However, smoking was significantly associated with clinical FD, postprandial fullness, and epigastric pain.

show abstract

Section: Discussionmentioning

confidence: 99%

Smoking Status and Prevalence of Upper Gastrointestinal Disorders

Esmaillzadeh¹,

Keshteli

Tabesh³

et al. 2014

Digestion

View full text Add to dashboard Cite

show abstract

“…A cohort study from New Zealand [5] and an Iranian study [6] reported similar poor association of GERD with the two obesity parameters. Other studies [1,2,7,8] have shown an increased prevalence of GERD in those with higher BMI. There are very few reports on BMI and WHR association with GERD symptoms.…”

mentioning

confidence: 87%

Is gastroesophageal reflux disease in south Indian population influenced by waist hip ratio and body mass index?

Mahalakshmi

Arunkumar

Trikudanathan

et al. 2015

Indian J Gastroenterol

View full text Add to dashboard Cite

It is widely believed that obesity, especially truncal, increases the risk of gastroesophageal reflux disease (GERD) particularly in the western population [1,2]. A high body mass index (BMI) [>25.0 kg/m 2 ] has been associated with increased risk of erosive esophagitis, Barrett's esophagus (BE), and adenocarcinoma [3]. Recent studies in the West have shown the waist to hip ratio (WHR), but not BMI, as the key factor associated with GERD complications [3]. We therefore intended to study whether typical and atypical GERD symptoms were associated with BMI and WHR abnormalities. We did a hospital-based case control study, recruiting consecutive cases attending the Department of Gastroenterology at Government Stanley Medical College Hospital, Chennai (tertiary care center catering to lower socioeconomic population) in 2009-2010, with typical GERD symptoms defined as heartburn, regurgitation, or combination of both and atypical GERD symptoms (noncardiac chest pain, chronic cough, unexplained otalgia, dysphonia). Minimum criterion for selection was presence of GERD symptoms at least once a week for 6 months. No symptom-based scoring system was used during the study. Controls were unmatched patients attending the same outpatient clinic with lower gastrointestinal (GI) symptoms or nonspecific abdominal pain with no upper GI or alarm symptoms like anorexia or weight loss. Patients with gastric outlet obstruction or previous gastric surgery causing secondary esophagitis were excluded. Baseline demographic details, weight, height, and waist and hip circumferences were obtained for all cases and controls. BMI and WHR were calculated from these. A BMI >23, WHR >0.90 (men), and >0.85 (women) were considered abnormal [4]. Analysis was done by gender, comparing cases and controls for demographic characteristics. Before analyzing the individual effect of BMI and WHR on GERD, the presence of any correlation between these two parameters was assessed in both men and women. Ethics committee of the institution (Stanley Medical College Hospital) approved the study. SPSS Version 20 was used for analysis: chi-square test for proportions, Wilcoxon sign rank sum test for comparison of median, and ANOVA for comparison of means. Odds ratio (OR) was computed only for significant risk factors with p<0.05.There were 107 men (+71 controls) and 152 women (+ 93 controls) with GERD symptoms. The median age among men and women in both cases and controls were similar (40 years). There were significantly more smokers (p < 0.005), alcoholics (p < 0.05), and tobacco chewers (p < 0.00001) among men with GERD. As BMI and WHR were not associated with each other in both genders (male r 2 0.049; female r 2 0.16), their effect on GERD symptoms was analyzed separately. The prevalence of typical and atypical GERD symptoms was similar in men and women (p not significant). In women, (Table 1) GERD symptoms were not influenced by a raised BMI (OR 1.3; 95 % confidence interval (CI) 1.0-1.6; p<0.05) and in fact, WHR was negatively associated with GERD (OR 0.8; 95 % ...

show abstract

“…A study that was derived from a population registry in Australia (Pandeya et al, 2012) found no evidence that frequent GERD symptoms were associated with coffee consumption. Similarly, a cross-sectional survey acquired via in-home interviews, convenience sampling, and targeted mailing, found no association between reflux disease and lifestyle choices such as coffee drinking (Friedenberg et al, 2010). Two studies from Italy revealed no correlation between coffee drinking and GERD (Nasseri-Moghaddam et al, 2008;Conio et al, 2002).…”

Section: Sources Of Informationmentioning

confidence: 99%

“…The abstracts of all these articles were reviewed and 15 were original epidemiological studies that evaluated the relationship between GERD and coffee (Pandeya et al, 2012;Bhatia et al, 2011;Lee et al, 2011;Friedenberg et al, 2010;Nasseri-Moghaddam, et al, 2008;Dore et al, 2008;El-Serag et al, 2007;Zheng et al, 2007;Somi et al, 2006;Moraes-Filho et al, 2005;Nilsson et al, 2004;Wang et al, 2004;Castelo Vega et al, 2003;Conio et al, 2002;Chang et al, 1997). These articles were reviewed decrease in the risk of reflux symptoms among people who drank more than seven cups of coffee per day compared with those who drank less than one cup (OR: 0.6; 95% CI: 0.4 − 0.7).…”

Section: Sources Of Informationmentioning

confidence: 99%

“…Although 5 studies found a relationship between coffee consumption and GERD, the majority of studies found no significant relationship (Pandeya et al, 2012;Friedenberg et al, 2010;Nasseri-Moghaddam et al, 2008;Dore et al, 2008;El-Serag et al, 2007;Zheng et al, 2007;MoraesFilho et al, 2005;Nilsson, et al, 2004;Conio et al, 2002;Chang et al, 1997). A study that was derived from a population registry in Australia (Pandeya et al, 2012) found no evidence that frequent GERD symptoms were associated with coffee consumption.…”

Section: Sources Of Informationmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Coffee on Gastroesophageal Reflux Disease

Chen

2013

FSTR

View full text Add to dashboard Cite

Coffee is the most popular drink in the world and coffee intake may be a risk factor for gastroesophageal reflux disease (GERD), which is a common disorder and its worldwide prevalence is increasing. However, the effect of coffee on GERD remains to be fully elucidated. The relationship between GERD and coffee consumption is not clear given the existing literature, whose results are diverse and contradictory. Existing systematic investigations are not adequate and further well-designed prospective studies are needed to clarify the effect of coffee on GERD.

show abstract

Prevalence and risk factors for gastroesophageal reflux disease in an impoverished minority population

Cited by 16 publications

References 40 publications

Smoking Status and Prevalence of Upper Gastrointestinal Disorders

Smoking Status and Prevalence of Upper Gastrointestinal Disorders

Is gastroesophageal reflux disease in south Indian population influenced by waist hip ratio and body mass index?

Effect of Coffee on Gastroesophageal Reflux Disease

Contact Info

Product

Resources

About