Prevalence and prognostic factors for erectile dysfunction in renal transplant recipients

Abstract

383ED is a common disorder in men aged 40 years and over. Prevalence of ED increases with age, with 25%, 55% and 65% of men aged 65, 75 and 80 years old, respectively, reporting the disorder. 4 In a cross-sectional study of sexual function of male kidney transplant recipients, ED was considerably more common than it was in the control population, with a prevalence of 55.7% despite the transplant recipients being younger than those in the control group. 5 In that study, age, time on dialysis, and iterative transplants were significantly and negatively related to erectile dysfunction . 5 The increased number of kidney transplants being performed in addition to the improved graft and patient survival rates has resulted in a greater number of patients with ED. 4 Thus, there is an increasing number of men experiencing a major quality of life issue. 4The literature regarding the effect of renal transplantation on patients with ED has been contradictory. In most studies, patients regain potency following renal transplant.2 However, in one longitudinal study, ED did not improve markedly after transplantation. 6 In other cases, particularly in patients who received second or subsequent transplantations, erectile function has been adversely affected by interference with penile arterial blood flow. 6 The purpose of this study was to determine the prevalence of ED at our institution in the postrenal transplant population. In addition, we compared several patient characteristics of patients in this population who had ED with those postrenal transplant patients who did not have ED. MethodsWe conducted a cross-sectional study of erectile function in male renal transplant recipiPrevalence and prognostic factors for erectile dysfunction in renal transplant recipients ORGINAL RESEARCH Abstract Introduction: The purpose of this study was to determine the prevalence of erec-

<p>Medication compliance and lifestyle adherence in renal transplant recipients in Kuwait</p>

“…This may be related to lower haemoglobin (HB) in the poorly compliant group or to associated post-transplant complications. This result was consistent with Wong et al, who demonstrated similar results 35. Physicians need to encourage their patients to discuss these issues in order to find appropriate solutions as only half of them consulted their nephrologists about their sexual problems.…”

Male sexual dysfunction in patients with chronic end-stage renal insufficiency and in renal transplant recipients

“…The score is recorded between a range of 2 and 30. Four categories can be identified depending on the score: the absence of disease (score 26-30), mild ED (17)(18)(19)(20)(21)(22)(23)(24)(25), moderate ED (11)(12)(13)(14)(15)(16), severe ED (< 10). The study considered all patients with ED with a score less than or equal to 25.…”

“…Other authors, instead, have focused their attention on immunosuppressive therapy: a study by Lee showed that the sirolimus (an immunosuppressant drug often used in combination with calcineurin inhibitors in renal transplant) results in a significant decrease in serum concentrations of testosterone (18). It was also postulated that the cyclosporin forms adversely affect the production of nitric oxide, an essential substrate in the complex mechanism of erection (19). So it is possible that the immunosuppressive therapy in transplant patients helps to maintain the endothelial and gonadic dysfunction that the previous uremic state had produced.…”

Nghiên Cứu Mối Liên Quan Giữa Rối Loạn Cương Dương Và Trầm Cảm Ở Bệnh Nhân Sau Ghép Thận Tại Bệnh Viện Bạch Mai

“…Trầm cảm làm nặng lên tình trạng rối loạn cương và ngược lại (r= -0,307, p = 0,000). Kết quả này cũng tương tự kết quả nghiên cứu của Araujo A.B và CS phân tích kết quả từ nghiên cứu "Massachusetts Male Aging Study" cho thấy rối loạn cương dương và trầm cảm có liên quan với nhau (OR: 1,82, 95% CI: 1,21-2,73) [5]. Trong nghiên cứu của chúng tôi, tỉ lệ bệnh nhân trầm cảm là 27,4%.…”