Prevalence and predictors of recurrence of major depressive disorder in the adult population

Hardeveld, Florian; Spijker, Jan; Graaf, Ron de; Nolen, W.A.; Beekman, Aartjan T.F.

doi:10.1111/j.1600-0447.2009.01519.x

Cited by 395 publications

(385 citation statements)

References 41 publications

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“…El porcentaje de episodios recurrentes encontrado es concordante con lo reportado por Retamal en Chile el 2004 (56%) 6 y lo publicado en estudios internacionales (37% a 85%) 17 .…”

Section: Discussionunclassified

Características clínicas del trastorno depresivo mayor en tratamiento en el nivel secundario de atención

Salvo

Saldivia

Parra³

et al. 2017

Rev. méd. Chile

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“…El porcentaje de episodios recurrentes encontrado es concordante con lo reportado por Retamal en Chile el 2004 (56%) 6 y lo publicado en estudios internacionales (37% a 85%) 17 .…”

Section: Discussionunclassified

Características clínicas del trastorno depresivo mayor en tratamiento en el nivel secundario de atención

Salvo

Saldivia

Parra³

et al. 2017

Rev. méd. Chile

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“…With a lifetime prevalence of around 16.2% (Kessler et al, 2003) and recurrence rates between 35% in the general population and 85% in specialized mental health facilities (Hardeveld, Spijker, De Graaf, Nolen, & Beekman, 2010), affective disorders (mainly major depression) belong to the second most frequent group of disorders (Wittchen & Jacobi, 2005). Therefore, early intervention in individuals with mild depressive symptoms—and prevention of major depressive disorder before it emerges—is of crucial importance for public health.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Vagal Control and Depressive Symptoms: The Moderating Role of Sleep Quality

Werner

Ford

Mauss

et al. 2016

Behavioral Sleep Medicine

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Lower cardiac vagal control (CVC) has been linked to greater depression. However, this link has not been consistently demonstrated, suggesting the presence of key moderators. Sleep plausibly is one such factor. Therefore, we investigated whether sleep quality moderates the link between CVC (quantified by high-frequency heart rate variability, HF-HRV) and depressive symptoms (assessed using established questionnaires) in 29 healthy women. Results revealed a significant interaction between HF-HRV and sleep quality in predicting depressive symptoms: participants with lower HF-HRV reported elevated depressive symptoms only when sleep quality was also low. In contrast, HF-HRV was not associated with depressive symptoms when sleep quality was high, suggesting a protective function of high sleep quality in the context of lower CVC.

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“…In a systematic review investigating recurrence of depression in specialized mental health care settings [9], recurrence rates up to 40 % already within a year after remission is reported. Possibly as a result of the above mentioned moderators, different outcomes in terms of recurrence rates are reported in primary and specialized health care.…”

Section: Introductionmentioning

confidence: 99%

12-Month Outcome and Predictors of Recurrence in Psychiatric Treatment of Depression: A Retrospective Study

2015

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Many individuals treated for depression suffer relapse or recurrence after treatment. Known risk factors include number of previous depressive episodes and residual symptoms after treatment. Both relapse/recurrence rates and predictors of relapse/recurrence, however, may differ between various settings. To perform a naturalistic evaluation of the sustained effectiveness of treatment for adult clinical depression in a psychiatric out-patient setting and to examine psychosocial and clinical predictors of relapse/recurrence. 51 individuals, who were successfully treated/discharged from psychiatric care 12 months prior, were assessed regarding current depressive status and regarding relapse and recurrence. Logistic regression was used to assess the predictive impact of the variables measured. At the 12-month follow-up, 26 % of the participants were in complete remission, 45 % were in partial remission, and 29 % were clinically depressed. In 1 year, 61 % suffered a new depressive episode. Having a greater number of previous episodes and having no partner significantly increased the risk of relapse or recurrence. A high prevalence of depression and partially remitted depression is reported at 12-month follow up, and a large proportion of the sample would likely benefit from active treatment. Relapse/recurrence rates are higher in this study than in many other studies, and it may be hypothesized that they are generally higher in psychiatric settings than in primary care. If so, this would indicate the need for a different treatment strategy in the psychiatric care of depression, with emphasis on long-term management of depression.

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Prevalence and predictors of recurrence of major depressive disorder in the adult population

Abstract: Clinical factors seem the most important predictors of recurrence. Data from studies performed in the general population and primary care on the recurrent course of MDD are scarce.

Cited by 395 publications

References 41 publications

Características clínicas del trastorno depresivo mayor en tratamiento en el nivel secundario de atención

Características clínicas del trastorno depresivo mayor en tratamiento en el nivel secundario de atención

Cardiac Vagal Control and Depressive Symptoms: The Moderating Role of Sleep Quality

12-Month Outcome and Predictors of Recurrence in Psychiatric Treatment of Depression: A Retrospective Study

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