“…Thus, outcome may be related to unidentified risk factors especially those evolving over time. Thus, we cannot exclude the effect of procedural and plaque characteristics to have an additional influence on clinical outcome in these patients, and increased coronary calcification has been described in patients with chronic kidney disease, 30,31 representing a moderate prognostic factor in this risk group. 32,33 Finally, we were unable to determine bleeding events in a systematicway.Becausebleedingisamajorrisk factor for post-PCI mortality and renal failure is associated with increased bleeding risk, 34 we cannot exclude a higher rate of major bleeding in patients with CKD being responsible for the higher mortality rate observed.…”