Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a Tertiary Hospital in Malaysia

Tham, Daniel; Abubakar, Usman; Tangiisuran, Balamurugan

doi:10.1007/s00431-019-03560-z

Cited by 16 publications

(16 citation statements)

References 25 publications

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“…In addition, the proportion of prescriptions containing at least one antibiotic was 41.50%. This result is similar to that found in Malaysia (43.5%) [ 33 ]. Significantly higher results are found in Nigeria (77.1%; 72.3%) [ 7 ], India (73.2%) [ 20 ] and Sierra Leone (74.8%) [ 8 ].…”

Section: Discussionsupporting

confidence: 91%

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

et al. 2021

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Introduction: Data on drug use in paediatrics are scarce in Senegal. The objective of this study was to assess the prescribing indicators in a paediatric population seen in an outpatient consultation at a Health Centre in Dakar, Senegal. Methods: A retrospective and analytical study was conducted. The study population consisted of prescriptions for children aged 0 to 14 years who were seen in ambulatory consultation between 1 June and 30 November 2019. The sample size was 600 prescriptions. The systematic survey was then conducted. Five prescription indicators recommended by the World Health Organization were calculated. The R software was used for descriptive analysis, bivariate analysis and binomial logistic regression. Results: The average number of drugs per prescription was 2.56. The proportion of drugs prescribed under the International Nonproprietary Name (INN) was 18.9%, while the proportion of drugs on the National Essential Medicines List (NEML) was 41.3%. The proportions of prescriptions with at least one antibiotic and one injectable product were 41.5% and 1.3%, respectively. Conclusions: This study showed that prescribing habits were inadequate. Thus, it would be necessary to move towards continuing training of prescribers in the wise use of medicines.

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Section: Discussionsupporting

confidence: 91%

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

et al. 2021

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“…In Malaysia and Nigeria, inappropriate use of antimicrobials in both hospital and community settings have been reported ( Ab Rahman et al, 2016;Abubakar et al, 2019;Tham et al, 2020). Hospital and community pharmacists, as experts on drugs and drug use, have an opportunity to improve the quality of antimicrobial use among patients through participation in AMS activities.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and self-reported confidence in antimicrobial stewardship programme among final year pharmacy undergraduate students in Malaysia and Nigeria

Abubakar

Sha’aban

Mohammed

et al. 2021

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Objective: This study evaluated the knowledge and self-reported confidence of antimicrobial stewardship (AMS) among pharmacy students in Malaysia and Nigeria. Methods: A cross-sectional study was conducted among final year undergraduate pharmacy students in a university from both Nigeria and Malaysia using a 59-item online questionnaire. Results: A total of 150 final year undergraduate pharmacy students completed the questionnaire. Exposure to infectious diseases clerkship was higher among the Malaysian students (78.2% versus 25.4%; p < 0.001). Overall, the knowledge score for antibiotic resistance and AMS were comparable (6.2 ± 1.5 and 3.6 ± 1.2, respectively versus 5.9 ± 1.6 and 3.3 ± 1.3). The knowledge of antibiotic therapy was higher among the Malaysian students (5.4 ± 1.8 versus 4.2 ± 1.8; p < 0.001) while self-reported confidence to participate in AMS was higher among the Nigerian students (median 48.0, IQR 26 – 75 versus median 36.5, IQR 15 – 75; p < 0.001). Conclusions: Pharmacy students in Malaysia and Nigeria have appreciable knowledge of antibiotic resistance, antibiotic therapy and AMS. More training on topics is recommended to improve the skills and competency of future pharmacists to participate in AMS.

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“…Antibiotics are the cornerstones of the treatment of bacterial infections and children received these drugs more frequently than any other class of medication (7). However, the improper and excessive use of antibiotics in children leads to resistance and ADRs (6)(7)(8). The high percentage of inadequate antibiotic prescriptions in hospitals and the community is reported in the pediatric population around the globe (8,9).…”

Section: Antibiotics and Childrenmentioning

confidence: 99%

“…However, the improper and excessive use of antibiotics in children leads to resistance and ADRs (6)(7)(8). The high percentage of inadequate antibiotic prescriptions in hospitals and the community is reported in the pediatric population around the globe (8,9). The prescription of these medicines is reported to be inappropriate in up to 30-50% of cases (9).…”

Section: Antibiotics and Childrenmentioning

confidence: 99%

“…The prescription of these medicines is reported to be inappropriate in up to 30-50% of cases (9). Antibiotics can also cause ADRs and drug toxicity on the intestinal microbiota and enteric immune system (8)(9)(10). The lack of relevant pediatric clinical trials on antibiotics has led to a shortage of evidence-based knowledge (11).…”

Section: Antibiotics and Childrenmentioning

confidence: 99%

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Antibiotic Usage in the Pediatric Population: The Need for Effective Role of Parents and Prescribers

Karataş¹,

Khan²

2021

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ÖzAntibiyotikler pediatrik tıbbi tedavinin önemli bir yönüdür ve enfeksiyon hastalıkları çocuk ölümlerinin önde gelen nedenidir. Antibiyotikler, bakteriyel enfeksiyonların tedavisinin temel taşıdır ve çocuklar bu ilaçları diğer ilaç sınıflarından daha sık almıştır. Antibiyotiklerin uygunsuz kullanımı uluslararası bir endişe kaynağıdır ve uygun ve güvenli antibiyotik kullanımının teşviki saatin ihtiyacıdır. Hastanelerdeki ve toplumdaki yetersiz antibiyotik reçetelerinin yüksek yüzdesi, dünya genelindeki pediatrik popülasyonda bildirilmektedir. Çocuklarda uygunsuz ve aşırı antibiyotik kullanımı direnç ve advers ilaç reaksiyonlarına (ADR'ler) yol açar. Ebeveynler ve reçete yazanlar, çocuklarda antibiyotik reçetesini etkiler. Hem ebeveynler hem de reçete yazanlar için doğru araçlarla, yalnızca doğru kişiler tarafından uygun eğitim müdahalesinin, uygun olmayan antibiyotik uygulamaları sorununu yeterince iyileştirebileceği ve antimikrobiyal direnç riskini kademeli olarak ortadan kaldırabileceği bildirilmektedir. Bu anlatı gözden geçirme belgesi, çocuklarda antibiyotiklerin kullanımı, ADR'ler, alerji, hatalar ve endikasyon dışı kullanımına genel bir bakış sağlamakta ve antibiyotik tedavisinin kullanımında ebeveynlerin ve reçete yazanın önemli rolünü tartışmaktadır.

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Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a Tertiary Hospital in Malaysia

Cited by 16 publications

References 25 publications

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

Knowledge and self-reported confidence in antimicrobial stewardship programme among final year pharmacy undergraduate students in Malaysia and Nigeria

Antibiotic Usage in the Pediatric Population: The Need for Effective Role of Parents and Prescribers

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