Prevalence and Persistence of Vitamin D Deficiency in Biliopancreatic Diversion Patients: A Retrospective Study

Abstract

This study gives evidence that vitamin D deficiency and insufficiency is prevalent in BPD patients. Despite excess weight loss and oral vitamin D supplementation, the data shows that vitamin D levels continue to decrease over time in BPD patients. Since the current method of vitamin D supplementation is not producing ideal results, other protocol needs to be developed.

Changes in Bone Metabolism in Morbidly Obese Patients After Bariatric Surgery: A Meta-Analysis

“…Although vitamin D levels did not change after surgery in the present study, many investigations reported incidences of vitamin D deficiency of 39-73 % after bariatric surgery [41,42]. Al-Shoha et al used bone biopsy results to demonstrate that gastric bypass operations predispose patients in high risk of bone loss populations to severe vitamin D deficiency and osteomalacia, indicating again that the supplement of vitamin D was not sufficient in specific cases [8].…”

The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications

“…The observation that obesity is associated with below-normal serum 25-hydroxyvitamin D concentrations and/or overt deficiency is not new; however, as obesity prevalence has grown, so have the number of reports in the literature regarding this phenomenon. [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] Some of the most recent information about low vitamin D status and obesity comes from studies in bariatric surgery patients, reporting low preoperative circulating levels of 25-hydroxyvitamin D. [21][22][23][24][25][26][27][33][34][35][36][37][38] In fact, a recent systematic review of 14 studies with about 1500 patients undergoing bariatric surgical procedures confirmed that obese individuals have serum 25-hydroxyvitamin D levels below 80 nmol l À1 preoperatively. 39 Other investigators have reported that body mass index (BMI) 25,26,[40][41][42][43][44][45][46] and body fat 20,45,…”

“…106 Given the physiology involved with oral vitamin D absorption, malabsorptive procedures such as the biliopancreatic diversion make vitamin D repletion and maintenance even more challenging. 37 Even the RYGB, which is not considered to be a purely malabsorptive procedure, but incorporates both restrictive and malabsorptive elements, presents challenges for vitamin D repletion, given that variable characteristics such as limb length can affect absorption. 24 There are limited data on how best to treat low vitamin D status in bariatric surgery patients, and procedure-specific guidelines are unavailable.…”

Impact of bariatric surgery on vitamin metabolisms in obese patients

“…К сожалению, уменьшение количества употребляемой пищи и сокращение всасывающей по-верхности тонкой кишки могут приводить к недостаточ-ности в организме микроэлементов, витаминов, вызывать развитие остеопороза, железо-и В 12 -дефицитной анемии, неврологических и других нарушений [2][3][4][5][6][7][8][9][10][11].…”