Prevalence and Perioperative Outcomes of Off-Label Total Hip and Knee Arthroplasty in the United States, 2000–2010

Malcolm, Tennison L.; Szubski, Caleb R.; Schiltz, Nicholas K.; Klika, Alison K.; Koroukian, Siran M.; Barsoum, Wael K.

doi:10.1016/j.arth.2015.05.020

Cited by 18 publications

(12 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…“Offlabel use” refers to use of medical devices for purposes or subpopulations other than those approved by the United States Food and Drug Administration (Malcolm et al. 2015 ). Malcolm et al.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Nationwide review of mixed and non-mixed components from different manufacturers in total hip arthroplasty

et al. 2016

View full text Add to dashboard Cite

Background and purposeCombining components from different manufacturers in total hip arthroplasty (THA) is common practice worldwide. We determined the proportion of THAs used in the Netherlands that consist of components from different manufacturers, and compared the revision rates of these mixed THAs with those of non-mixed THAs.Patients and methodsData on primary and revision hip arthroplasty are recorded in the LROI, the nationwide population-based arthroplasty register in the Netherlands. We selected all 163,360 primary THAs that were performed in the period 2007–2014. Based on the manufacturers of the components, 4 groups were discerned: non-mixed THAs with components from the same manufacturer (n = 142,964); mixed stem-head THAs with different manufacturers for the femoral stem and head (n = 3,663); mixed head-cup THAs with different head and cup manufacturers (n = 12,960), and mixed stem-head-cup THAs with different femoral stem, head, and cup manufacturers (n = 1,773). Mixed prostheses were defined as THAs (stem, head, and cup) composed of components made by different manufacturers.Results11% of THAs had mixed components (n = 18,396). The 6-year revision rates were similar for mixed and non-mixed THAs: 3.4% (95% CI: 3.1w–3.7) for mixed THAs and 3.5% (95% CI: 3.4–3.7) for non-mixed THAs. Revision of primary THAs due to loosening of the acetabulum was more common in mixed THAs (16% vs. 12%).InterpretationOver an 8-year period in the Netherlands, 11% of THAs had mixed components—with similar medium-term revision rates to those of non-mixed THAs.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Malcolm et al. ( 2015 ) demonstrated that the prevalence of offlabel THAs and TKAs was 30% and 37%, respectively, in the USA. They predicted an increase in the prevalence of off-label arthroplasties in the future.…”

Section: Discussionmentioning

confidence: 99%

Nationwide review of mixed and non-mixed components from different manufacturers in total hip arthroplasty

et al. 2016

View full text Add to dashboard Cite

show abstract

“…[ 1 , 2 ] With the aging of the US population, the number of TKR is expected to obviously increase by 2030, reaching estimated 3.48 million a year. [ 3 , 4 ] In the acute stage after surgery, TKR can lead to obvious pain, and the postoperative knee pain has become a familiar and persistent chief complaint after the TKR, leading to patient poor life quality and dissatisfaction. The reported incidence of severe postoperative knee pain after TKR ranges from 10.3% to 36.8%.…”

Section: Introductionmentioning

confidence: 99%

Femoral nerve block versus obturator nerve block for pain management after total knee replacement

Zhang

Lin²,

Zhang³

et al. 2020

Medicine

View full text Add to dashboard Cite

Background: Several studies reported short-term analgesic efficacy of obturator nerve block (ONB), as in comparison with the femoral nerve block (FNB) in the treatment of postoperative pain after the total knee replacement (TKR). The optimal method remains under debate. The purpose of our current work is to compare the safety and efficacy of FNB and ONB for postoperative analgesia after TKR. Methods: This prospective, randomized, and controlled study was performed from January 2018 to December 2019. It was authorized via the Institutional Review Committee in NO.971 Hospital of the People's Liberation Army Navy (2019-PLAN-132). Two hundred patients were divided randomly into 2 groups, the control group (n = 100) and study group (n = 100). The experimental group received FNB and control groups received ONB. Primary outcome included pain at different time point (Visual Analogue Scale score of anterior knee pain at rest and in motion). The Visual Analogue Scale scores were marked by patients themselves on a paper with a graduated line starting at 0 (no pain) and ending at 10 (the most painful). Opioid consumption was converted to equivalents of oral morphine uniformly for statistical analysis. Secondary outcomes included the knee range of motion, the hospital stay length as well as the postoperative complications such as pulmonary embolism and deep vein thrombosis. Results: Table 1 will show the clinical outcomes between the 2 groups. Conclusion: This trial would provide an evidence for the use of different types of peripheral nerve blocks in TKR.

show abstract

“…[ 1 , 2 ] In the wake of the aging of the US population, the number of knee arthroplasty is expected to obviously increase by 2030, with the estimated 3.48 million cases each year. [ 3 , 4 ] Although UKA recovers faster than total knee arthroplasty, with better function and fewer complications, it is related to serious postoperative pain. There are many methods for the treatment of the postoperative pain, containing block of femoral nerve, local infiltration anesthesia, and intravenous opioids as well as intrathecal analgesia, [ 5 – 7 ] the management of pain after the UKA is challenging in orthopedic field.…”

Section: Introductionmentioning

confidence: 99%

The efficacy and safety of multiple versus single doses dexamethasone in unicompartmental knee arthroplasty

Gao¹,

Liu²,

Zhang

et al. 2020

Medicine

View full text Add to dashboard Cite

Background: Concerns exist regarding the analgesia effect and safety of multiple versus single doses dexamethasone in unicompartmental knee arthroplasty. There is an urgent need of studies that efficiently control for confounding, conduct comprehensive and consecutive observation of potential risks of the dexamethasone administration, and investigate its clinical applicability. We thus further designed a randomized controlled study to assess the different dose of dexamethasone on postoperative pain and complications in patients undergoing unicompartmental knee arthroplasty. Methods: This randomized, prospective, controlled study was carried out between January 2018 and August 2019. It was approved by the institutional review board in our hospital (HBRM2020013). A total of 80 patients were randomly assigned to each group: the study group (n = 40) and the control group (n = 40). All surgical procedures were performed by a similar orthopedic surgeon. In the study group, patients received intravenously 20 mg dexamethasone (4 mL, Tianjin Kingyork group Co., Ltd., China) just after the anesthesia, and repeated at 24 hours after the surgery. Patients in the control group received intravenously 10 mg dexamethasone solution (2 mL) just after the anesthesia, and repeated at 24 hours after the surgery. CRP, IL-6, VAS pain scores at rest and walking, the VAS scores of nausea, and the incidence of postoperative vomiting and nausea (POVN) were recorded at 24, 48, and 72 hours postoperatively. Conclusion: We hypothesized that patients receiving multiple doses of dexamethasone was associated with better outcomes compared with patients receiving single dose of dexamethasone. Trial registration: This study protocol was registered in Research Registry (researchregistry5770).

show abstract

Prevalence and Perioperative Outcomes of Off-Label Total Hip and Knee Arthroplasty in the United States, 2000–2010

Cited by 18 publications

References 32 publications

Nationwide review of mixed and non-mixed components from different manufacturers in total hip arthroplasty

Nationwide review of mixed and non-mixed components from different manufacturers in total hip arthroplasty

Femoral nerve block versus obturator nerve block for pain management after total knee replacement

The efficacy and safety of multiple versus single doses dexamethasone in unicompartmental knee arthroplasty

Contact Info

Product

Resources

About