Prevalence and pattern of bacteraemia among HIV-infected under -five children in a tertiary hospital in Kano, Nigeria

Abstract

Abstract:Background: Bacterae-

Transitioning to Automated Microbiologic Era: Blood Culture Isolates in Children and Adults in Federal Teaching Hospital in Gombe, North East Nigeria 2016-2020

“…Salmonella isolation in this study was low and was in older children and young adults. This is similar to studies from Kano [69], Uyo [71] and Ilorin [92] but in contrast to reports from North central and North western Nigeria where only children 5 years and below where studied [17]. Salmonella BSI was high in studies in children with protein energy malnutrition [43], Sickle Cell Disease [44] and HIV [69] in Nigeria.…”

“…This is similar to studies from Kano [69], Uyo [71] and Ilorin [92] but in contrast to reports from North central and North western Nigeria where only children 5 years and below where studied [17]. Salmonella BSI was high in studies in children with protein energy malnutrition [43], Sickle Cell Disease [44] and HIV [69] in Nigeria. In a population based, multi-country Ty-phoid fever Surveillance in Africa Programme [93] in which Nigeria was not included, the most frequent non-contaminant bacteria isolated were S. typhi 24%, Non-Typhoidal Salmonella 17%, S. aureus 12%, E. coli 8%, and Streptococcus pneumoniae.…”

“…In Nigeria, Staph aureus was the most commonly reported isolate in paediatric studies from Central Nigeria [11], Lagos [15], Maiduguri [46], Kano [69], Ekiti [70], Uyo [71]. A recent study from Uganda [72] and a systemic review and meta-analysis of the aetiologic agents of neonatal sepsis in Sub-Saharan Africa [73] established Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae respectively as the predominant aetiologic agents.…”

Nasal carriage of meticillin-resistant Staphylococcus aureus among children living with HIV attending Infectious Diseases Clinics in Kano, Nigeria

“…[ 6 , 7 ] Data obtained from a study in African countries showed that the median prevalence of resistance to oxacillin (an antibiotic used in laboratories to test for meticillin resistance) in S. aureus isolated from febrile patients was 13.4% for West Africa and 8.0% for East Africa [ 6 ]. In hospitalised children living with HIV (CLWH) who have bloodstream infections in Kano, S. aureus accounted for 4/19 (21%) of the isolates [ 8 ]. All four isolates were resistant to oxacillin [ 8 ].…”

“…In hospitalised children living with HIV (CLWH) who have bloodstream infections in Kano, S. aureus accounted for 4/19 (21%) of the isolates [ 8 ]. All four isolates were resistant to oxacillin [ 8 ].…”