Prevalence and Metabolic Factors of Hyperuricemia in an Elderly Agricultural and Fishing Population in Taiwan

Yu, Qian; Shen, Hsiu-Nien; Hu, Yichun; Chen, Yu-Fen; Tung, Tao‐Hsin

doi:10.5606/archrheumatol.2017.6075

Cited by 10 publications

(9 citation statements)

References 25 publications

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“…Based on the obtained data, we estimated the population prevalence of hyperuricemia at 23.1% among older adults, and 25.5% in women and 19.2% in men. This makes the Polish prevalence one of the highest in older populations reported worldwide [27,[38][39][40][41][42][43]. This is caused by the inclusion of a large percentage of octa-and nonagenarians, with a 1.48-times higher frequency of hyperuricemia in relation to younger seniors.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles—Results from a Population-Based PolSenior Study

Winder

Owczarek

Mossakowska

et al. 2021

IJERPH

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Background: Our study analyzes the frequency and risk factors of hyperuricemia and the use of allopurinol in a representative cohort of the older Polish adult population. Methods: The analysis was a part of a cross-sectional PolSenior study on aging in Poland. The complete medication data were available in 4873 out of 4979 community dwelling respondents aged 65 and over. Serum uric acid concentrations were evaluated in 4028 participants (80.9% of the cohort). Results: Hyperuricemia was observed in 28.2% of women and 24.7% of men. Ten risk factors of hyperuricemia were selected based on multivariable LASSO logistic regression analysis. Nine factors showed significant odds ratios: eGFR < 60 mL/min/1.73 m2 (OR = 4.10), hypertriglyceridemia (OR = 1.88), obesity (OR = 1.75), heart failure (1.70), CRP > 3.0 mg/dL (OR = 1.64), coronary artery disease (OR = 1.30), use of loop-diuretics (OR = 4.20), hydrochlorothiazide (OR = 2.96), and thiazide-like diuretics (OR = 2.81). Allopurinol was used by 2.8% of men and 1.8% of women. The therapy was considered effective in 46.7% of men and 53.3% of women. Conclusions: Hyperuricemia was present in 23.1% (95% CI: 21.8–24.4) of the older Polish population. The frequency of hyperuricemia increases with age, reaching 30.5% in men and 33.7% in women aged 90 years or more. Chronic kidney disease, obesity, heart failure, hypertriglyceridemia, and the use of diuretics were the strongest risk factors for hyperuricemia in older adults. The treatment with allopurinol was ineffective in more than half of participants.

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Section: Discussionmentioning

confidence: 99%

“…and women over the age of 65, respectively [41,42]. The highest incidence of hyperurice mia was found in Ireland, reaching 27.7% in 60-80-year-olds and 43.0% in people over 8 years of age [43].…”

Section: Study Populationmentioning

confidence: 94%

Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles—Results from a Population-Based PolSenior Study

Winder

Owczarek

Mossakowska

et al. 2021

IJERPH

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“…In Indonesia according to the World Health Organization in 2013, the prevalence of hyperuricemia was 81% [4]. While a study in North Halmahera also showed that the prevalence of hyperuricemia was high, namely, 60% (men 50.83% and women 69.17%) [5].…”

Section: Introductionmentioning

confidence: 99%

“…In Taiwan the prevalence of hyperuricemia is 30.4%, in men (30.2%), and women (30.6%). This prevalence will increase significantly with age [4].…”

Section: Introductionmentioning

confidence: 99%

Effect of the Stems Lemongrass (Cymbopogon citratus) in Pallumara and Pepes Anchovy (Stolephorus Sp.) to Uric Acid Levels of Hyperuricemia Elderly Women

Maulid

Bahar

Sirajuddin

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Compliance with food-base dietary guidelines has been known delivered positive effect on nutrition and public health. AIM: The aim of the study was to assess the effect of lemongrass stems in pallumara and anchovy pepes on changes in uric acid levels in elderly women in hyperuricemia. METHODS: This research is a quasi-randomized pre-test-post-test control group design experiment. The study sample was elderly women with hyperuricemia who met the inclusion and exclusion criteria of 45 persons divided into two intervention groups and one control group. The first group was given lemongrass stems in pallumara anchovy, the second group was given lemongrass stems in anchovy pepes, and the control group only consumed family food. Data were analyzed using paired t test, one-way ANOVA, Chi-square, and Kruskal–Wallis. RESULTS: The results showed that a significant change in uric acid levels in both intervention groups (p = 0.001 < 0.05), whereas the control group was not significant. There was a difference in changes in uric acid levels between the intervention group and the control group (p = 0.000 < 0.05). CONCLUSION: It was concluded that the large difference in uric acid levels between the intervention group and the control group was 26.5% and 28.3%. It is recommended to use lemongrass in preventing elevated blood uric acid levels.

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“…The prevalence of hyperuricemia is increasing worldwide (Yu et al, 2017;Zhu et al, 2017). Elevated serum uric acid levels are associated with increment of mortality rate (Jung et al, 2018;Yu et al, 2017) and lifestyle-related disease such as chronic renal failure (Yamamoto et al, 2018;Chen et al, 2019;Lai et al, 2018;Yu et al, 2017;Zhang et al, 2018;Li et al, 2018), cardiovascular disease (Ozalp Kizilay et al, 2019;Jung et al, 2018;Okazaki et al, 2017;Yu et al, 2017;Zhang et al, 2018;Zhu et al, 2017;Yamamoto et al, 2018), hyperglycemia (Takir et al, 2015;Zhu et al, 2017;Wardhana and Rudijanto, 2018;Ozalp Kizilay et al, 2019), elevated glycated hemoglobin (HbA1c) (Wardhana and Rudijanto, 2018), insulin resistance (Ozalp Kizilay et al, 2019;Wardhana and Rudijanto, 2018), increased risk of diabetes mellitus (Kuwabara et al, 2017;Ozalp Kizilay et al, 2019;Wardhana and Rudijanto, 2018;Yu et al, 2017;Zhang et al, 2018;Zhu et al, 2017) and obesity (Zhu et al, 2017;Ali et al, 2018;Zhang et al, 2016). Recent studies revealed that maybe there is a bilateral association between hyperuricemia and obesity, and they influence each other based on multiple mechanisms (Ozalp Kizilay et al, 2019;Han et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Association of uric acid with metabolic parameters and obesity

Mahdavi-Roshan¹,

Movahedian

Varkaneh

et al. 2020

NFS

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Purpose Recent studies have shown that hyperuricemia is a predictor of non-communicable disease and an increment of mortality rate. Also, elevated serum uric acid may be associated with obesity in the adult population. This study aims to evaluate the association between serum uric acid levels with metabolic parameters and risk of obesity in the Iranian population. Design/methodology/approach The cross-sectional study was done on 550 participants, who were referred to a hospital for elective angiography in Rasht, Iran; anthropometric indices (waist circumference (WC) and body mass index (BMI)) and hematological factors were measured using the standard approaches. Based to the angiography results, the severity of atherosclerosis was defined. Findings The mean (SD) concentration of serum uric acid for all participants was 5.15 (1.37) mg/dl. Individuals who were at the highest tertile had higher mean (SD) of weight (p = 0.004), creatinine and blood urea nitrogen (p < 0.001) lower fasting blood sugar (FBS) (p = 0.000) and HbA1c (p = 0.016), and they were mostly men compared with those in the lowest tertile. After adjusting for confounders, FBS (ß = –0.145, p = 0.001) and HbA1c (%) (ß = –0.130, p = 0.019) had inverse and weight (ß = 0.156, p = 0.001) had direct association with serum uric acid. After adjustment for additionally potential confounders subjects in the highest tertile of serum uric acid had 92 per cent higher chance of obesity compared with subjects in the lowest tertile (OR 1.92; 95 per cent CI 1.13, 3.23). Originality/value The present study has concluded that increase serum uric acid related to high risk of obesity and low mean of FBS and HbA1c.

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Prevalence and Metabolic Factors of Hyperuricemia in an Elderly Agricultural and Fishing Population in Taiwan

Cited by 10 publications

References 25 publications

Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles—Results from a Population-Based PolSenior Study

Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles—Results from a Population-Based PolSenior Study

Effect of the Stems Lemongrass (Cymbopogon citratus) in Pallumara and Pepes Anchovy (Stolephorus Sp.) to Uric Acid Levels of Hyperuricemia Elderly Women

Association of uric acid with metabolic parameters and obesity

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