Prevalence and management of delirium in intensive care units in the Netherlands: An observational multicentre study

Berger, Elke; Wils, Evert‐Jan; Vos, Piet; Santen, Susanne van; Koets, Jeroen; Slooter, Arjen J. C.; Woude, Meta van der; Koopmans, Matty; Rinket, Martin A.; Hoiting, Oscar; Hoogendoorn, Emma E.; Streefkerk, Jörn O.; Vreede, Els W. de; Riekerk, Bea; Simons, Koen S.; Toscano, Eryk; Schoonderbeek, F. Jeannette; Hofstra, Lieuwe S.; Oever, Huub L. A. van den; Raben, Adrienne; Holman, Susanne; Nooteboom, Fleur G. C. A.; Bethlehem, Carina; Cate, J.T.M. Houwink Ten; Verkade, Martijn A.; Mijzen, Lisa J.; Ginkel, Janneke M. de Man‐van; Vermeulen, Hester; Boogaard, Mark van den

doi:10.1016/j.iccn.2020.102925

Cited by 11 publications

(3 citation statements)

References 26 publications

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“…e finding of the current study was in line with the hypothesis that sepsis cause activation of the systematic inflammatory response and release of cytokines and/or bacterial toxins that may disrupt the bloodbrain barrier, causing hypoxia, cerebral metabolic changes, and inadequate cerebral perfusion, resulting in delirium [45]. Similar results about the significant association between ICU delirium and sepsis were reported in previous studies [17,54,55]. It was observed that presence of bladder catheter was associated with delirium, also observed in other studies [34,56,57].…”

Section: Discussionsupporting

confidence: 92%

Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman

Al-Hoodar

Lazarus

Omari

et al. 2022

Critical Care Research and Practice

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Background. The incidence of delirium is high up to 46.3% among patients admitted to ICU. Delirium is linked to negative patient outcomes like increased duration of mechanical ventilation use, prolonged ICU stay, increased mortality rate, and healthcare costs. Despite the importance of delirium and its consequences that are significant, there is a scarcity of studies which explored delirium in Oman. Objectives. This study was conducted to assess the incidence of delirium, the association between the selected predisposing factors and precipitating factors with delirium, determine the predicators of delirium, and evaluate its impacts on ICU mortality and ICU length of stay among ICU patients in Oman. Methods. A multicenter prospective observational design was used. A total of 153 patients were assessed two-times a day by bedside ICU nurses through the Intensive Care Delirium Screening Checklist (ICDSC). Results. The results revealed that the delirium incidence was 26.1%. Regression analysis showed that sepsis, metabolic acidosis, nasogastric tube use, and APACHE II score were independent predictors for delirium among ICU patients in Oman and delirium had significant impacts on ICU length of stay and mortality rate. Conclusion. Delirium is common among ICU patients and it is associated with negative consequences. Multidisciplinary prevention strategies should be implemented to identify and treat the modifiable risk factors.

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Section: Discussionsupporting

confidence: 92%

Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman

Al-Hoodar

Lazarus

Omari

et al. 2022

Critical Care Research and Practice

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show abstract

“…In this study, 23.6% of patients presented at least one episode of delirium, which is consistent with literature (Berger et al, 2020;Salluh et al, 2015). Our results are also in line with those reported in CAM-ICU validation studies involving research nurses (Chanques et al, 2018;Ely et al, 2001).…”

Section: Discussionsupporting

confidence: 93%

“…With an expected precision of 10%, we aimed to demonstrate that the lower limit of the 95% confidence interval (CI) for CNAs' delirium screening sensitivity would be 74% or higher. Assuming an incidence rate of 20% for delirium (Berger et al, 2020), a sample of 258 CNAs' CAM-ICU assessments was required to ensure power. To account for a 5% risk of post-hoc exclusions and missing data, a total sample size of 270 triplets of CAM-ICU assessment was planned.…”

Section: Sample Size Calculationmentioning

confidence: 99%

Monitoring delirium in the intensive care unit: Diagnostic accuracy of the CAM-ICU tool when performed by certified nursing assistants – A prospective multicenter study

Alaterre

Fazilleau

Cayot-Constantin³

et al. 2023

Intensive and Critical Care Nursing

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Screening for delirium in the intensive care unit using eDIS-ICU – A purpose-designed app: A pilot study

Sutt

Flaws

Gunn

et al. 2021

Australian Critical Care

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Prevalence and management of delirium in intensive care units in the Netherlands: An observational multicentre study

Cited by 11 publications

References 26 publications

Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman

Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman

Monitoring delirium in the intensive care unit: Diagnostic accuracy of the CAM-ICU tool when performed by certified nursing assistants – A prospective multicenter study

Screening for delirium in the intensive care unit using eDIS-ICU – A purpose-designed app: A pilot study

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