Prevalence and incidence of diabetic retinopathy in patients with diabetes of Latin America and the Caribbean: A systematic review and meta-analysis

Abstract

Objectives This systematic review aimed to assess the prevalence and incidence of diabetic retinopathy in patients with diabetes of Latin America and the Caribbean. Methods We searched Web of Science (WoS)/Core Collection, WoS/MEDLINE, WoS/Scielo, Scopus, PubMed/Medline and Embase databases until January 16, 2023. We meta-analyzed prevalences according to type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Results Forty-three prevalence studies (47 585 participants) and one incidence study (436 participants) were included. The overall prevalence of retinopathy in patients with T1DM was 40.6% (95% CI: 34.7 to 46.6; I2: 92.1%) and in T2DM was 37.3% (95% CI: 31.0 to 43.8; I2: 97.7), but the evidence is very uncertain (very low certainty of evidence). In meta-regression, we found that age (T1DM) and time in diabetes (T2DM) were factors associated with the prevalence. On the other hand, one study found a cumulative incidence of diabetic retinopathy of 39.6% at 9 years of follow-up. Conclusions Two out of five patients with T1DM or T2DM may present diabetic retinopathy in Latin America and the Caribbean, but the evidence is very uncertain. This is a major public health problem, and policies and strategies for early detection and opportunely treatment should be proposed.

Retrospective Study of Diabetic Retinopathy and Macular Edema in Southern Part of Bangladesh

“…For people with type-2 diabetes mellitus (DM) who have had the condition for a long time, diabetic retinopathy (DR) is the leading cause of concern [ 1 – 5 ]. Patients with diabetes mellitus are often ignorant of diabetic retinopathy, and managing their condition over a number of years is now the primary source of suffering [ 6 – 8 ]. Diabetic retinopathy (DR) and blindness can be avoided if blood glucose levels are monitored often and kept within the recommended range [ 9 ].…”