Prevalence and incidence of cognitive impairment and dementia in heart failure – A systematic review, meta-analysis and meta-regression

Yap, Nicole Li Xian; Kor, Qianyi; Teo, Yao Neng; Teo, Yao Hao; Syn, Nicholas; Evangelista, Lauren Kay Mance; Tan, Benjamin Yq; Lin, Weiqin; Yeo, Leonard Ll; Kong, William; Chong, Y. F.; Wong, Raymond Cc; Poh, Kian Keong; Yeo, Tiong‐Cheng; Sharma, Vijay Kumar; Chai, Ping; Chan, Mark Y; Goh, Fang Qin; Sia, Ching‐Hui

doi:10.1016/j.hjc.2022.07.005

Cited by 11 publications

(9 citation statements)

References 110 publications

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“…In this study of Veterans with heart failure, ICD-based algorithms estimated ADRD prevalences of 17% and 29%, consistent with the pooled results of 32 prior studies finding a percentage (95% CI) of 20% (13%-28%). 6 The inter-rater reliability between the CCW and VA-developed ADRD algorithms was substantially greater than would be expected by random chance. However, the two algorithms classified nearly 1 in 8 Veterans differently.…”

Section: Discussionmentioning

confidence: 90%

Identifying Alzheimer's disease and related disorders via diagnostic codes in Veterans with heart failure

Bayer,

Jiang,

Kunicki

et al. 2023

J American Geriatrics Society

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Section: Discussionmentioning

confidence: 90%

Identifying Alzheimer's disease and related disorders via diagnostic codes in Veterans with heart failure

Bayer,

Jiang,

Kunicki

et al. 2023

J American Geriatrics Society

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“…Items are rated using a 4-point (0-3) scale, with greater scores indicating elevated distress. Scores for each subscale range from 0 to 21 and can be categorized as normal (0-7), mild (8-10), moderate (11)(12)(13)(14), or severe (15)(16)(17)(18)(19)(20)(21).…”

Section: Psychological Measuresmentioning

confidence: 99%

“…Moreover, reports on the frequency of CI in persons with heart failure (HF) are varied, being between 25% and 75% [ 15 , 16 ]. Further, a recent meta-analysis of 119 studies has established the overall prevalence of CI and dementia in patients with HF as 41.42% and 19.79%, respectively [ 17 ]. Research has also shown that patients with HF report up to a four-fold higher risk of presenting with cognitive dysfunction, particularly in attentional and memory domains, when compared with the general population, and that the overall prevalence of CI in outpatients with HF is as high as 50% [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Executive Attentional Dyscontrol as a Core Cognitive and Behavioral Feature of Individuals with Obesity and Cardiovascular Disease: A Cross-Sectional Investigation

et al. 2023

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Executive attention as a frontal domain ability that is effective in potentially blocking distracting information, reconciling conflicts among simultaneous attentional demands, and regulating impulsive behavior may be impaired in individuals with obesity and cardiovascular disease (CVD). This study aimed (i) to explore the presence of selected cognitive (global cognitive impairment, sensitivity to interference, and attention) and psychological (quality of life, depression, anxiety, and impulsivity) dimensions and (ii) to examine the interactive relationship between attentional dyscontrol—both as a psychological and as a cognitive measure—and the above-mentioned variables in a sample of patients with CVD attending a cardiac rehabilitation program across different body mass index (BMI) levels. Clinical information of 104 patients with CVD was retrospectively collected. Participants were classified into three groups according to their BMI as follows: normal weight (NW = 30), overweight (OW = 19), and obese (OB = 55). Individuals with CVD and a higher BMI showed problems in controlling executive attention—through both neuropsychological and behavioral measures. Specifically, OB patients demonstrated reduced sensitivity to cognitive interference, lower capabilities in divided attention during visual-tracking tasks, and greater impulsivity compared to NW patients. This behavioral characteristic was also found to be correlated with higher levels of anxiety and depression and a lower quality of life. Implications for cognitive rehabilitation were discussed to offer directions for better management of patients with CVD and obesity.

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“…Comorbidity is defined as “the presence of more than 1 disorder in a person in a defined period of time.” [ 8 ] HF readmissions were related to no cardiovascular causes and directly associated with an increasing number of comorbidities. Studies have shown that some noncardiac comorbidities, such as chronic kidney disease, [ 9 ] diabetes, [ 10 ] peripheral vascular disease, [ 11 ] and dementia, [ 12 ] increase the risk of HF readmission. The Charlson comorbidity index (CCI) combines both disease numbers and severity into a comorbidity-weighted index.…”

Section: Introductionmentioning

confidence: 99%

The Charlson comorbidity index and short-term readmission in patients with heart failure: A retrospective cohort study

et al. 2023

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The relationship between the Charlson comorbidity index (CCI) and short-term readmission is as yet unknown. Therefore, we aimed to investigate whether the CCI was independently related to short-term readmission in patients with heart failure (HF) after adjusting for other covariates. From December 2016 to June 2019, 2008 patients who underwent HF were enrolled in the study to determine the relationship between CCI and short-term readmission. Patients with HF were divided into 2 categories based on the predefined CCI (low < 3 and high > =3). The relationships between CCI and short-term readmission were analyzed in multivariable logistic regression models and a 2-piece linear regression model. In the high CCI group, the risk of short-term readmission was higher than that in the low CCI group. A curvilinear association was found between CCI and short-term readmission, with a saturation effect predicted at 2.97. In patients with HF who had CCI scores above 2.97, the risk of short-term readmission increased significantly (OR, 2.66; 95% confidence interval, 1.566–4.537). A high CCI was associated with increased short-term readmission in patients with HF, indicating that the CCI could be useful in estimating the readmission rate and has significant predictive value for clinical outcomes in patients with HF.

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Prevalence and incidence of cognitive impairment and dementia in heart failure – A systematic review, meta-analysis and meta-regression

Cited by 11 publications

References 110 publications

Identifying Alzheimer's disease and related disorders via diagnostic codes in Veterans with heart failure

Identifying Alzheimer's disease and related disorders via diagnostic codes in Veterans with heart failure

Executive Attentional Dyscontrol as a Core Cognitive and Behavioral Feature of Individuals with Obesity and Cardiovascular Disease: A Cross-Sectional Investigation

The Charlson comorbidity index and short-term readmission in patients with heart failure: A retrospective cohort study

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