Prevalence And Impact Of Myofascial Pain Syndrome In Relapsing-Remitting Multiple Sclerosis And The Effects Of Local Anesthetic Injections For Short-Term Treatment

Tutuncu, Mesude; Ertem, Devrimsel Harika; Soysal, Aysun

doi:10.1016/j.msard.2020.102528

Cited by 2 publications

(3 citation statements)

References 34 publications

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“…Taken together, our results suggest that the worse the physical impairment at relapse, as evaluated by MSIS-29 PHY and MSWS-12 (but not EDSS), the worse the pain in people with MS. In most studies, EDSS does not correlate with the intensity of pain [ 15 , 16 , 17 ]. For example, Michalski et al evaluated the severity and quality of pain in people with MS. and did not find significant differences in the EDSS scores of participants with and without pain.…”

Section: Discussionmentioning

confidence: 99%

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The Impact of Relapses on Pain and Quality of Life in Patients with Multiple Sclerosis Treated with Corticosteroids

Rakusa,

Chataway,

Hardy

2023

Pharmaceuticals

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Background: We assessed the prevalence and risks associated with pain during and after a multiple sclerosis (MS) relapse, and the impact of pain on quality of life (QoL), in MS patients. Methods: 117 patients suffering an acute MS relapse were evaluated with clinician- and patient-reported outcomes, including the expanded disability status scale (EDSS), Multiple Sclerosis Impact Scale (MSIS-29), and MS Walking scale-12 (MSWS-12). Relapse-related pain was assessed via the short-form 36 (SF-36) questionnaire upon first visit (relapse onset) and at 6 weeks after treatment with intravenous methylprednisolone (follow-up visit). Results: Pain was present in 80% of patients at relapse onset. Patients with pain were more impaired physically (higher mean scores on MSIS-29phys and MSWS-12 and lower mean scores on SF-36 role physical, physical, and vitality scales) at relapse and six weeks after. In total, 74% of patients with MS relapse reported a poorer QoL due to pain. A lower psychological well-being was correlated with greater pain (MSIS29psy score). An increased number of prior relapses was a predictor of more pain at relapse onset. Conclusions: Pain was common at the time of MS relapse and improved, but was still significant, six weeks after treatment with corticosteroids. Further studies are required to better understand relapse-related pain.

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Section: Discussionmentioning

confidence: 99%

“…They treated their pain with local anaesthetic injections. Three months after treatment, there were no differences in the EDSS scores between respondents and non-respondents [ 15 ]. In another study, Ate et al studied neuropathic pain in people with relapsing-remitting MS and secondary progressive MS.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Relapses on Pain and Quality of Life in Patients with Multiple Sclerosis Treated with Corticosteroids

Rakusa,

Chataway,

Hardy

2023

Pharmaceuticals

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“…5 Another study found 51.9% of 137 patients treated for multiple sclerosis had been diagnosed with MPS. 6 Therefore, the development of strategies for relief of pain related to MTrPs is a critical public health issue.…”

Section: Introductionmentioning

confidence: 99%

Is Exercise Rehabilitation an Effective Adjuvant to Clinical Treatment for Myofascial Trigger Points? A Systematic Review and Meta-Analysis

Zhou

Liu

et al. 2023

JPR

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Purpose To systematically evaluate the effect of exercise rehabilitation as an adjuvant to clinical treatment for myofascial trigger points (MTrPs). Patients and Methods ESBCO, PubMed, Science Direct, Web of Science, China Knowledge Network (CNKI), and Wanfang databases were comprehensively searched from database inception date through July 2022. Randomized controlled trials comparing MTrPs treatments that included exercise rehabilitation with a single clinical treatment. Two researchers independently screened articles using inclusion/exclusion criteria, scored methodologic quality, and extracted data including patient demographics, interventions, and outcomes. Results We included 14 RCTs (N = 734). Results showed short-term (mean difference [MD], −2.25; 95% confidence interval [CI], −4.08 to −0.41; Z = 2.40; P = 0.02) and long-term (MD = −0.47; 95% CI: −0.80 to −0.17; Z = 3.05; P = 0.02) adjuvant exercise rehabilitation treatments were superior in reducing musculoskeletal pain intensity to single clinical treatment in controls, but long-term versus short-term effectiveness was not significantly different. The exercise rehabilitation group more effectively increased the range of motion (ROM) (standardized mean difference [SMD], 1.04; 95% CI: 0.32 to 1.77; Z = 2.84; P = 0.005) and decreased dysfunction (SMD = −0.93; 95% CI: −1.82 to −0.05; Z = 2.06; P = 0.04) than controls; no significant difference was observed in the pressure pain threshold (PPT) between two groups. Conclusion Exercise rehabilitation as an adjuvant to clinical treatment for MTrPs was moderately effective in relieving pain intensity, increasing ROM, and improving dysfunction versus single clinical intervention. These findings must be validated by larger, higher-quality studies.

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Prevalence And Impact Of Myofascial Pain Syndrome In Relapsing-Remitting Multiple Sclerosis And The Effects Of Local Anesthetic Injections For Short-Term Treatment

Cited by 2 publications

References 34 publications

The Impact of Relapses on Pain and Quality of Life in Patients with Multiple Sclerosis Treated with Corticosteroids

The Impact of Relapses on Pain and Quality of Life in Patients with Multiple Sclerosis Treated with Corticosteroids

Is Exercise Rehabilitation an Effective Adjuvant to Clinical Treatment for Myofascial Trigger Points? A Systematic Review and Meta-Analysis

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