Prevalence and Genotypic Identification of Human Papillomavirus Infection in a Population from Northwestern Spain

Abstract

We present a cross-sectional observational descriptive study that was carried out on a reference population of 84,000 women from Northwestern Spain in order to study the prevalence of human papillomavirus (HPV) and its repercussion in genital cancer. The group of patients for this study was of 436 patients with ages ranging from 16 to 80 years old. Three samples were taken from each woman in this group from the cervix and vagina, which was, later, processed using PCR techniques. The most predominant serotype was PHPV-16, followed by HPV-31. Type 1 CIN (low grade cervical intraepithelial neoplasia) (LG-CIN) was the most predominant.

Knowledge of HIV and HPV Infection, and Acceptance of HPV Vaccination in Spanish Female Sex Worker

“…The diagnosis of high grade-cervical intraepithelial neoplasia (HG-CIN) should be incorporated into the population tumor records. Cost-benefit analysis programs should be initiated for the implemented screening programs [17,18].…”

Impact of HPV Infection on the Quality of Life in Young Women

“…Studies on women who have had anomalous Pap Test results have highlighted psychological consequences like anxiety, fear of cancer, sexual problems, changes in body image, difficulty in reproductive functions, hypochondria, a sense of neglect, anger, and fear of being labelled [6][7][8].…”

Human Papilloma Virus (HPV) and Genital Cancer

“…The International Agency for Cancer Research (IACR), which belongs to the WHO, classifies HPV types 16 and 18 as carcinogenic and types 31 and 33 as probably carcinogenic [1]. More recently, based on data from 11 studies carried out in various countries, in which the relationship between the cervix and HPV have been studied, 15 high-risk oncological viral strains have been identified (HR-HPV) (16,18,31,33,35,39,45, 51, 52,56, 58, 59, 68, 73 y 82); strains 26, 53 and 66 have been classified as possible high-risk, and strains 6,11,40,42,43,44,54,61,70,72, 81 and CP6108 have been classified as low-risk (LR-HPV) [2].…”

“…Clinical forms, generally caused by low oncological risk HPV strains (6,11), are generally benign. Sub-clinical forms include both benign lesions and lesions with pre-malignant potential, and are generally caused by high oncological risk HPV strains (16 and 18).…”

“…The sequence which, possibly, exists in the high grade lesions is associated with infection by high-risk HPV strains, albeit not exclusively. Co-infections by HPV-16 and HPV-58 appear to be especially dangerous [6].…”