Prevalence and Genetic Diversity of Aichi Virus Strains in Stool Samples from Community and Hospitalized Patients

Ambert-Balay, Katia; Lorrot, Mathie; Bon, Fabienne; Giraudon, H.; Kaplon, Jérôme; Wolfer, M.; Lebon, Pierre; Gendrel, D.; Pothier, Pierre

doi:10.1128/jcm.02140-07

Cited by 140 publications

(173 citation statements)

References 22 publications

Supporting

Mentioning

155

Contrasting

Order By: Relevance

“…The sex ratio was 1.26. The mean Vesikari score was 11.7 (standard deviation, 3.16; range, [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. Among the 95 sets of data rejected in this study, 13 were rejected for the lack of clinical data and 82 for the absence of a faecal sample.…”

Section: Study Population and General Screeningmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France

Lorrot

Bon

Hajje

et al. 2010

Eur J Clin Microbiol Infect Dis

Self Cite

View full text Add to dashboard Cite

International audienceRotavirus is recognised as the most important agent of severe acute gastroenteritis (AGE) in young children. In a 2-year prospective survey, we investigated the epidemiology and clinical features of the viral and bacterial pathogens in children hospitalised for AGE. The study was performed in a Parisian teaching hospital from November 2001 to May 2004. Clinical data were prospectively collected to assess the gastroenteritis severity (20-point Vesikari severity score, the need for intravenous rehydration, duration of hospitalisation). Stools were systematically tested for group A rotavirus, norovirus, astrovirus and adenovirus 40/41, sapovirus and Aichi virus and enteropathogenic bacteria. A total of 457 children (mean age 15.9 months) were enrolled. Viruses were detected in 305 cases (66.7%) and bacteria in 31 cases (6.8%). Rotaviruses were the most frequent pathogen (48.8%), followed by noroviruses (8.3%) and adenoviruses, astroviruses, Aichi viruses and sapoviruses in 3.5%, 1.5%, 0.9% and 0.4%, respectively. Cases of rotavirus gastroenteritis were significantly more severe than those of norovirus with respect to the Vesikari score, duration of hospitalisation and the need for intravenous rehydration. Rotaviruses were the most frequent and most severe cause in children hospitalised for AGE, and noroviruses also account for a large number of cases in this population

show abstract

Section: Study Population and General Screeningmentioning

confidence: 99%

“…In contrast, the role of Aichi viruses, which belong to the picornavirus family, is not well known [6,7].…”

mentioning

confidence: 99%

Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France

Lorrot

Bon

Hajje

et al. 2010

Eur J Clin Microbiol Infect Dis

Self Cite

View full text Add to dashboard Cite

show abstract

“…Aichi viruses were detected by RT-PCR using primer set Ai6261 and Ai6779 targeting the RNA polymerase gene (43) and a OneStep RT-PCR kit from Qiagen (2).…”

Section: Methodsmentioning

confidence: 99%

“…In infants, group A rotavirus (RV) is the major etiologic agent of viral gastroenteritis and is responsible for 29 to 45% of hospitalizations, depending on the income level of the country (32,33). Other enteric viruses such as human norovirus (NoV), sapovirus, astrovirus (HAstV), adenovirus (HAdV) types 40 and 41, and Aichi virus are also associated with acute gastroenteritis, and their relative importance in high-income countries has been reported previously (2,4).…”

mentioning

confidence: 99%

Acute Infantile Gastroenteritis Associated with Human Enteric Viruses in Tunisia

et al. 2008

View full text Add to dashboard Cite

, investigated the incidence and the clinical role of various enteric viruses responsible for infantile gastroenteritis in 632 Tunisian children presenting in dispensaries (380 children) or hospitalized (252 children) for acute diarrhea. At least one enteric virus was found in each of 276 samples (43.7%). A single pathogen was observed in 234 samples, and mixed infections were found in 42 samples. In terms of frequency, rotavirus and norovirus were detected in 22.5 and 17.4% of the samples, respectively, followed by astrovirus (4.1%), Aichi virus (3.5%), adenovirus types 40 and 41 (2.7%), and sapovirus (1.0%). The seasonal distribution of viral gastroenteritis showed a winter peak but also an unusual peak from May to September. The severity of the diarrhea was evaluated for hospitalized infants. No significant differences were observed between rotavirus and norovirus infections with regard to the incidence and the clinical severity of the disease, especially in dehydration.Diarrhea is one of the major causes of morbidity and mortality among infants throughout the world, especially in developing countries, where malnutrition and poor local health service are factors responsible for the increased severity of the diarrhea. In infants, group A rotavirus (RV) is the major etiologic agent of viral gastroenteritis and is responsible for 29 to 45% of hospitalizations, depending on the income level of the country (32, 33). Other enteric viruses such as human norovirus (NoV), sapovirus, astrovirus (HAstV), adenovirus (HAdV) types 40 and 41, and Aichi virus are also associated with acute gastroenteritis, and their relative importance in high-income countries has been reported previously (2, 4).Human NoVs, which are members of the Caliciviridae family, are found in all age groups (7, 10) and are a major cause of food-and water-related outbreaks (11,22). Recent work has showed that NoVs are the second most frequent etiologic agents of viral gastroenteritis (16). Sapovirus, another genus of the family Caliciviridae, HAstV (41), and enteric type 40 and 41 HAdVs have also been associated with diarrhea. Aichi virus (42) has recently been classified into the Kobuvirus genus in the Picornaviridae family and has been associated with oyster consumption.Although the role of these viruses in outbreaks of gastroenteritis in industrialized countries has been established (7, 29), little is known about their contribution to outbreaks in developing countries and few data are currently available (25). In Tunisia, a middle-income Mediterranean country, earlier studies showed the contribution of RVs (8, 38) and more recently that of HAstVs and HAdVs (12) in cases of childhood diarrhea. However, the nature of the contribution of NoVs and Aichi viruses to outbreaks of gastroenteritis in Tunisia remains unknown.The aim of this study was to determine the incidence of these enteric viruses and their contribution to diarrheal diseases in Tunisian children. We conducted a prospective 2-year study of children who were hospitalized in or presented to ...

show abstract

“…Although there are no known human cases of infections caused by spotted fever group (SFG) rickettsiae in Taiwan, novel strains of SFG rickettsiae have been isolated as recently described (6,7). In addition, evidence for R. felis infections in cat and cat fl ea populations has been identifi ed by using immunofl uorescence assay (IFA), PCR, and organism isolation (K.-H.Tsai et al, unpub.…”

Section: Human Case Of Rickettsia Felis Infection Taiwanmentioning

confidence: 99%

Candidate New Species ofKobuvirusin Porcine Hosts

Reuter¹,

Boldizsár²,

Kiss³

et al. 2008

Emerg. Infect. Dis.

120

View full text Add to dashboard Cite

Prevalence and Genetic Diversity of Aichi Virus Strains in Stool Samples from Community and Hospitalized Patients

Cited by 140 publications

References 22 publications

Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France

Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France

Acute Infantile Gastroenteritis Associated with Human Enteric Viruses in Tunisia

Candidate New Species ofKobuvirusin Porcine Hosts

Contact Info

Product

Resources

About