Prevalence and Factors Associated with Anxiety and Depression Amongst Hospitalised COVID-19 patients in Laquintinie Hospital Douala, Cameroon

Abstract

Introduction: Studies assessing the mental health of patients with COVID-19 infection remain limited. Disasters and major emergencies, not just COVID-19, undoubtedly lead to greater incidence of mental health problems. Previous studies indicate that the novel Coronavirus disease can cause panic and stress in patients. Our literature search didn’t reveal any previous published data from Cameroon and the Central African sub-region. In order to bridge this gap, we assessed the prevalence and factors associated with depression and anxiety in COVID-19 patients.Methods: We carried out a cross-sectional study in a secondary hospital in the Littoral Region of Cameroon. We recruited hospitalised COVID-19 patients during a 4-month period. We collected data on sociodemographic characteristics. The HADS score was used to assess levels of anxiety and depression. All analysis were done using Stata 14. A P value of <0.05 was used as the cut-off for statistical significance.Results: A total number of 285 patients took part in this study with a mean age of 48.47 years. The prevalence of anxiety in COVID-19 patients was 60.35% while the prevalence of depression was 81.40%. At multivariate logistic regression male gender (OR: 1.89, P=0.04), hypoxaemia (OR: 2.20, P=0.01), presence of COVID-19 complications (OR: 1.61, P= 0.02) and current episode of depression (OR: 4.14, P<0.01) were independently associated with anxiety. Similarly, age > 35 years (OR:2.03, P= 0.02), presence of comorbidity (OR: 1.68, P= 0.01), BMI > = 30kg/m2 (OR: 1.78, P= 0.02), presence of COVID-19 complications (OR: 1.28, P= 0.01) and anxiety (OR: 4.60, P<0.001) were independently associated with depression. Conclusion: Hospitalised patients with COVID-19 experienced high levels of anxiety and depression. Treatment of hospitalised patients with COVID-19 should therefore include psychotherapy and psychiatric support.