Prevalence and Disease Burden of Hyperhidrosis in the Adult Population

Augustin, Matthias; Radtke, Marc Alexander; Herberger, Katharina; Kornek, Thomas; Heigel, H; Schaefer, Ines

doi:10.1159/000351292

Cited by 80 publications

(93 citation statements)

References 13 publications

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“…Comparable studies regarding hyperhidrosis from northern Europe are few, and factors such as research method and climate might affect the results of a population survey. The prevalence of PH (5.5%) in our study does not show the extreme variation that has been described for the disease compared to larger studies from Europe and the USA [2,5] . Similar to the mentioned studies, we are also able to describe that one quarter of those with PH have severe problems with sweating and that the prevalence of PH decreases with higher age groups while in SH it was increased.…”

Section: Discussioncontrasting

confidence: 84%

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Prevalence and Characteristics of Hyperhidrosis in Sweden: A Cross-Sectional Study in the General Population

Shayesteh

Janlert²,

Brulin

et al. 2016

Dermatology

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Background: Hyperhidrosis is defined as excessive sweating which can be primary or secondary. Data about the prevalence of primary hyperhidrosis are scarce for northern Europe. Objective: Our aim was to investigate the prevalence of hyperhidrosis focusing on its primary form and describe the quality of life impairments for the affected individuals. Methods: Five thousand random individuals aged 18-60 years in Sweden were investigated. The individuals' addresses were obtained from Statens personadressregister, SPAR, which includes all persons who are registered as resident in Sweden. A validated questionnaire regarding hyperhidrosis including the Hyperhidrosis Disease Severity Scale (HDSS) and 36-item Short Form (SF-36) health survey was sent to each individual. The participants were asked to return the coded questionnaire within 1 week. Results: A total of 1,353 individuals (564 male, 747 female and 42 with unspecified gender) with a mean age of 43.1 ± 11.2 years responded. The prevalence of primary hyperhidrosis was 5.5%, and severe primary hyperhidrosis (HDSS 3-4 points) occurred in 1.4%. Secondary hyperhidrosis was observed in 14.8% of the participants. Our SF-36 results showed that secondary hyperhidrosis causes a significant (p < 0.001) impairment of both mental and physical abilities while primary hyperhidrosis impairs primarily the mental health (p < 0.001). Conclusion: Hyperhidrosis affects individuals in adolescence as a focal form while occurring as a generalised form with increasing age. Further, the prevalence of primary hyperhidrosis described in our study is comparable to other studies from the western hemisphere. While secondary, generalised hyperhidrosis impairs both physical and mental aspects of life, primary hyperhidrosis, with the exception of severe cases, mainly affects the mental health.

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Section: Discussioncontrasting

confidence: 84%

“…In another study from Germany, where 14,336 individuals aged between 16 and 70 years were investigated, it was described that 4.6% suffered from PH and 16.3% suffered from both PH and SH [5] .…”

mentioning

confidence: 99%

Prevalence and Characteristics of Hyperhidrosis in Sweden: A Cross-Sectional Study in the General Population

Shayesteh

Janlert²,

Brulin

et al. 2016

Dermatology

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“…This includes limitations in work and social relationships, physical and leisure activities, and impairments in emotional and mental health [1, 2, 4, 12, 17, 20]. The negative impact caused by excessive sweating has been reported to be similar to, if not greater than, the negative impact caused by conditions, such as psoriasis and other chronic diseases [5, 17].…”

Section: Introductionmentioning

confidence: 99%

“…Prevalence estimates of primary (focal) hyperhidrosis outside of the United States are all higher and vary widely, ranging from 4.6 % in Germany, 5.5 % in Sweden, 12.3 % in Vancouver, Canada, 12.8 % in Japan, and 14.5 % in Shanghai, China [1, 7, 16, 20]. Prevalence estimates that include both primary and secondary hyperhidrosis range from 13.9 % in Japan, 16.3 % in Germany, 16.7 % in Vancouver, 18.4 % in Shanghai, and 20.3 % in Sweden [1, 7, 16, 20].…”

Section: Introductionmentioning

confidence: 99%

Hyperhidrosis: an update on prevalence and severity in the United States

Walker²,

et al. 2016

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Current published estimates of the prevalence of hyperhidrosis in the United States are outdated and underestimate the true prevalence of the condition. The objectives of this study are to provide an updated estimate of the prevalence of hyperhidrosis in the US population and to further assess the severity and impact of sweating on those affected by the condition. For the purposes of obtaining prevalence, a nationally representative sample of 8160 individuals were selected using an online panel, and information as to whether or not they experience hyperhidrosis was obtained. The 393 individuals (210 female, 244 non-Hispanic white, 27 black, mean age 40.3, SE 0.64) who indicated that they have hyperhidrosis were asked further questions, including body areas impacted, severity of symptoms, age of onset, and socioemotional impact of the condition. Current results estimate the prevalence of hyperhidrosis at 4.8 %, which represents approximately 15.3 million people in the United States. Of these, 70 % report severe excessive sweating in at least one body area. In spite of this, only 51 % have discussed their excessive sweating with a healthcare professional. The main reasons are a belief that hyperhidrosis is not a medical condition and that no treatment options exist. The current study’s findings with regard to age of onset and prevalence by body area generally align with the previous research. However, current findings suggest that the severity and prevalence are both higher than previously thought, indicating a need for greater awareness of the condition and its associated treatment options among medical professionals.

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“…Several recent epidemiologic studies have demonstrated a greater prevalence among young, working-age individuals, who are most commonly affected and often seek healthcare professionals [4,5,6]. …”

Section: Introductionmentioning

confidence: 99%

Oxybutynin for the Treatment of Primary Hyperhidrosis: Current State of the Art

Campanati

Gregoriou

Kontochristopoulos

et al. 2015

Skin Appendage Disord

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Oxybutynin is an anticholinergic drug with an emerging role in the treatment of hyperhidrosis. Several recent studies have documented that it is effective both in focal and generalized hyperhidrosis and shows universally good response among different groups of patients regardless of age, gender, and weight. The most common adverse event is dry mouth reported by almost all patients treated. The way this might affect long-term compliance and tolerability should be better investigated in the future.

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Prevalence and Disease Burden of Hyperhidrosis in the Adult Population

Cited by 80 publications

References 13 publications

Prevalence and Characteristics of Hyperhidrosis in Sweden: A Cross-Sectional Study in the General Population

Prevalence and Characteristics of Hyperhidrosis in Sweden: A Cross-Sectional Study in the General Population

Hyperhidrosis: an update on prevalence and severity in the United States

Oxybutynin for the Treatment of Primary Hyperhidrosis: Current State of the Art

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