Prevalence and Determinants of COPD in Spain: EPISCAN II

Soriano, Joan B.; Alfageme, Inmaculada; Miravitlles, Marc; Lucas, Pilar de; Soler-Cataluña, Juan José; García‐Río, Francisco; Casanova, Ciro; González-Moro, José Miguel Rodríguez; Cosío, Borja G.; Sánchez, Guadalupe; Ancochea, Julio

doi:10.1016/j.arbres.2020.07.024

Cited by 112 publications

(95 citation statements)

References 33 publications

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“…Second, it is worth mentioning that the number of women included in our population was low. This was because, although we recruited the patients consecutively, COPD is far more prevalent in men than in women in our area [20], resulting in the latter being underrepresented. However, we know that COPD has a different impact on women and that the male/female gap affects various areas of the disease, including inhaled therapies [21][22][23].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Suboptimal Peak Inspiratory Flow in Patients with Stable COPD

Represas-Represas

Aballe-Santos

Fernández-García³

et al. 2020

JCM

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Objective: Although the importance of assessing inspiratory flow in the selection of treatments for chronic obstructive pulmonary disease (COPD) is understood, evaluation of this factor is not yet widespread or standardized. The objective of the present work was to evaluate the peak inspiratory flow (PIF) of patients with COPD and to explore the variables associated with a suboptimal PIF. Methods: An observational, cross-sectional study was carried out at specialized nursing consultations over a period of 6 months. We collected clinical data as well as data on symptoms, treatment adherence, and patient satisfaction with their inhalers via questionnaires. PIF was determined using the In-Check Dial G16® device (Clement Clarke International, Ltd., Harlow, UK). In each case, the PIF was considered suboptimal when it was off-target for any of the prescribed inhalers. The association with suboptimal PIF was evaluated using multivariate logistic regression and the results were expressed as the odds ratio (OR) with 95% confidence interval (CI). Results: A total of 122 COPD patients were included in this study, of whom 34 (27.9%) had suboptimal PIF. A total of 229 inhalers were tested, of which 186 (81.2%) were dry powder devices. The multivariate analysis found an association between suboptimal PIF and age (OR = 1.072; 95% CI (1.019, 1.128); p = 0.007) and forced vital capacity (OR = 0.961; 95% CI (0.933, 0.989); p = 0.006). Conclusions: About a third of patients in complex specialized COPD care have suboptimal PIFs, which is related to age and forced vital capacity.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Suboptimal Peak Inspiratory Flow in Patients with Stable COPD

Represas-Represas

Aballe-Santos

Fernández-García³

et al. 2020

JCM

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“…The reason to include only those aged 35 years or over is the very low prevalence of COPD among those aged under this age in Spain. 15 …”

Section: Methodsmentioning

confidence: 99%

“…The reason to include only those aged 35 years or over is the very low prevalence of COPD among those aged under this age in Spain. 15 Our study population includes subjects discharged with a primary diagnosis of ischemic stroke identified with the ICD-10 codes shown in Supplementary Table S1.…”

Section: Study Populationmentioning

confidence: 99%

Sex Differences in the Incidence and Outcomes of COPD Patients Hospitalized with Ischemic Stroke in Spain: A Population-Based Observational Study

Miguel-Díez

López‐de‐Andrés

Jiménez‐García

et al. 2021

COPD

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Purpose To compare the incidence, clinical characteristics and outcomes of patients admitted with ischemic stroke (IS) according to the presence of COPD and sex in Spain (2016–2018). Patients and Methods We selected all admissions with IS (≥35 years) included in the Spanish National Hospital Discharge Database. We matched each patient suffering COPD with a non-COPD patient with identical age, sex, IS type and year of hospitalization. Results IS was coded in 92,524 men and 79,731 women (8.67% with COPD). The incidence of IS was higher in COPD men than in non-COPD men (IRR 1.04; 95% CI 1.03–1.06), although the differences were not significant among women. COPD men had twice higher incidence of IS than COPD women (IRR 2.00; 95% CI 1.93–2.07). After matching, COPD men had a higher in-hospital mortality (IHM) than non-COPD men (11.48% vs 9.80%; p<0.001), and the same happened among women (14.09% vs 11.96%; p=0.002). COPD men received thrombolytic therapy less frequently than non-COPD men. For men and women, the risk of dying in the hospital increased with age, some comorbidities and mechanical ventilation use. After multivariable adjustment, COPD increased the risk of IHM in men (OR 1.16; 95% CI 1.06–1.28) and women (OR 1.12; 95% CI 1.01–1.27). Finally, among COPD patients, being women increased the risk of dying during the hospitalization with IS by 15% (OR 1.15; 95% CI 1.03–1.28). Conclusion Incidence of IS was higher in COPD patients, although the difference was only significant for men. COPD was associated with an increased risk of IHM. Among COPD patients, women had higher IHM.

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“…Furthermore, its prevalence, morbidity, and mortality are increasing [2]. According to the most recent prevalence study with clinical measurements conducted in Spain, the overall estimated prevalence of COPD among adults aged 40 years or over was 11.8% (95% confidence interval (CI) 11.2-12.5) [3]. Much of the disease burden and healthcare use in COPD patients is related to the management of their comorbidities.…”

Section: Introductionmentioning

confidence: 99%

Sex Differences in the Effects of COPD on Incidence and Outcomes of Patients Hospitalized with ST and Non-ST Elevation Myocardial Infarction: A Population-Based Matched-Pair Analysis in Spain (2016–2018)

de-Miguel-Díez

Jiménez-García

Hernández‐Barrera

et al. 2021

JCM

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We aimed to compare the incidence, clinical characteristics, and outcomes of patients admitted with myocardial infarction (MI), whether ST elevation MI (STEMI) or non-ST elevation MI (NSTEMI), according to the presence of chronic obstructive pulmonary disease (COPD), and to identify variables associated with in-hospital mortality (IHM). We selected all patients with MI (aged ≥40 years) included in the Spanish National Hospital Discharge Database (2016–2018). We matched each patient suffering COPD with a non-COPD patient with identical age, sex, type of MI, and year of hospitalization. We identified 109,759 men and 44,589 women with MI. The MI incidence was higher in COPD patients (incident rate ratio (IRR) 1.32; 95% confidence interval (CI) 1.29–1.35). Men with COPD had higher incidence of STEMI and NSTEMI than women with COPD. After matching, COPD men had a higher IHM than non-COPD men, but no differences were found among women. The probability of dying was higher among COPD men with STEMI in comparison with NSTEMI (odds ratio (OR) 2.33; 95% CI 1.96–2.77), with this risk being higher among COPD women (OR 2.63; 95% CI 1.75–3.95). Suffering COPD increased the IHM after an MI in men (OR 1.14; 95% CI 1.03–1.27), but no differences were found in women. COPD women had a higher IHM than men (OR 1.19; 95% CI 1.01–1.39). We conclude that MI incidence was higher in COPD patients. IHM was higher in COPD men than in those without COPD, but no differences were found among women. Among COPD patients, STEMI was more lethal than NSTEMI. Suffering COPD increased the IHM after MI among men. Women with COPD had a significantly higher probability of dying in the hospital than COPD men.

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Prevalence and Determinants of COPD in Spain: EPISCAN II

Cited by 112 publications

References 33 publications

Evaluation of Suboptimal Peak Inspiratory Flow in Patients with Stable COPD

Evaluation of Suboptimal Peak Inspiratory Flow in Patients with Stable COPD

Sex Differences in the Incidence and Outcomes of COPD Patients Hospitalized with Ischemic Stroke in Spain: A Population-Based Observational Study

Sex Differences in the Effects of COPD on Incidence and Outcomes of Patients Hospitalized with ST and Non-ST Elevation Myocardial Infarction: A Population-Based Matched-Pair Analysis in Spain (2016–2018)

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