Prevalence and Covariates of Polypharmacy in Elderly Patients on Discharge from a Tertiary Care Hospital in Oman

Al‐Hashar, Amna; Sinawi, Hamed Al; Mahrizi, Anwar Al; Al-Hatrushi, Manal

doi:10.5001/omj.2016.85

Cited by 31 publications

(45 citation statements)

References 25 publications

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“…Anti-infectious were also associated with polypharmacy due to the high prevalence of infectious diseases as reported previously [46]. These findings are similar to findings reported by previous studies that reported a high prevalence of administration of cardiovascular system drugs, drugs acting on blood and blood forming organ, alimentary tract and metabolism drugs and anti-infectious drugs [23,25,34,46].…”

Section: Association With Comorbidities and Drug Classificationsupporting

confidence: 82%

“…Another study conducted in Dubai reported that 89% of the participated patients were taking more than five medications [29]. Our results were comparable to a study conducted in Oman on discharged geriatrics and reported polypharmacy in 76.3% of the participants [23].…”

Section: Prevalence Of Pddi and Polypharmacysupporting

confidence: 81%

“…Most studies that examined the prevalence of polypharmacy were conducted in the inpatient setting [8,[22][23][24][25][26]. However, in this study we investigated the prevalence of polypharmacy in the outpatient settings to capture a more comprehensive insight.…”

Section: Prevalence Of Pddi and Polypharmacymentioning

confidence: 99%

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The prevalence of drug-drug interactions and polypharmacy among elderly patients in Jordan

Al‐Qerem¹,

Jarrar²,

Al-Sheikh³

et al. 2018

biomedicalresearch

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Background: The number of people aged 60 or older is estimated to be 5.6% among Jordanian population, those elderly people need special medical care; since they have a greater prevalence of chronic diseases and therefore subjected to higher prevalence of polypharmacy and potential drug-drug interaction (pDDI). There is no data about polypharmacy and pDDI in elderly patients among the Jordanian population. Methods: Prescriptions for patients aged 60 or older were examined and those patients were interviewed in several community pharmacies and hospitals' outpatient pharmacies. The interviews covered factors that may affect the possibility of pDDI and polypharmacy including patient's education level, number of doctors the patient see, number of drugs the patient take, does the patient live alone and does the patient take the medication by himself. Results: 367 (51.5% male and 48.5% female) patients were interviewed and their prescriptions examined. The data showed that 334 (91%) had at least one pDDI of those 67 (18.3%) had a major pDDI and 281 (76.6%) had at least one moderate pDDI. Polypharmacy was found in 275 (74.9%) of the participants. Factors that were associated with incidence of major pDDI included polypharmacy, taking Alimentary tract and metabolism drugs or drugs acting on blood and blood forming organ, and patient taking medication by him/herself. Several factors were associated with moderate pDDI including seeing a general practitioner, while polypharmacy was associated with education level and number of diseases. Conclusion: High incidence of major and moderate pDDI and polypharmacy was found. This study emphasizes the need for a better control over elderly prescription in Jordan

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Section: Association With Comorbidities and Drug Classificationsupporting

confidence: 82%

Section: Prevalence Of Pddi and Polypharmacysupporting

confidence: 81%

See 1 more Smart Citation

The prevalence of drug-drug interactions and polypharmacy among elderly patients in Jordan

Al‐Qerem¹,

Jarrar²,

Al-Sheikh³

et al. 2018

biomedicalresearch

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show abstract

“…This is comparable with the study done in Ayder referral hospital, Tigray, Ethiopia which showed that infection diseases were diagnosed in 58.6% of the study participant [20]. However according to the retrospective study done in Oman [6], more patients had CVD on admission (31%) followed by infection (23.0%) and GIT diseases (13%). This might be consistent with the possible reason that CVD are highly prevalent among higher income countries while infection is common among developing countries including Ethiopia.…”

Section: Discussionsupporting

confidence: 67%

“…There is no standard cut point with regard to the number of medications that is agreed up on for the definition of poly-pharmacy [5]. The definition of poly-pharmacy varies in the literature, but it ranges from the concurrent use of two or more to five or more prescription drugs [6]. However, it is mostly defined as the concurrent use of four or more prescription drugs [7,8].…”

Section: Introductionmentioning

confidence: 99%

Polypharmacy and the Contributing Factors Among Elderly Patients in Shashemene Referral Hospital, West Arsi, Oromia Region, Ethiopia

Geresu¹,

Yadesa²,

Abebe³

2017

J Bioanal Biomed

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Examining the relationship between depression and medication adherence among elderlies suffering from cardiovascular disease referring to the clinics affiliated with Kermanshah University of Medical Sciences: A cross‐sectional study

Brimavandi,

Abbasi,

Khaledi‐Paveh

et al. 2023

Health Science Reports

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BackgroundIn recent years, around 30% of all mortalities worldwide has been related to cardiovascular disease (CVD). The most important predictor solution of cardiovascular events is enhancing medication adherence. Meanwhile, the main reason behind development of physical disorders among the elderly is depression. In this regard, the present research was performed to determine the relationship between depression and medication adherence among the elderly suffering from CVD.MethodsA cross‐sectional study was done via an analytical approach on 188 elderlies fulfilling the inclusion criteria. The participants were chosen through convenience nonrandomized sampling from March to July 2022. The data were collected through demographic and healthcare information form plus Madanloo chronic disease medication adherence and geriatric depression scale. The analysis of the data was done by SPSS 26 plus Stata 14.2.ResultsThe mean depression score was 5.6(4.3) and the mean score of medication adherence in the elderlies was 168.03(23.85). The prevalence of depression was higher in women than in men (p = 0.015), and the elderlies differing from heart failure reported the minimum extent of medication adherence. The findings obtained from analysis of variance showed that age, level of education, and monthly level of income were among the effective demographic factors in the extent of depression and medication adherence (p < 0.05). Meanwhile, 26% of changes in medication adherence can be attributed to depression. Further, the results of the multiple linear regression model reported that depression, age, and polypharmacy are among the predictors of medication adherence.Discussion and ConclusionA weak to moderate relationship existed between depression and medication adherence among these elderlies. Given the growing elderly population, the importance of depression, and lack of medication adherence in incidence of CVD events, it is recommended to train the healthcare team to monitor the elderly regarding depression symptoms.

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Prevalence and Covariates of Polypharmacy in Elderly Patients on Discharge from a Tertiary Care Hospital in Oman

Cited by 31 publications

References 25 publications

The prevalence of drug-drug interactions and polypharmacy among elderly patients in Jordan

The prevalence of drug-drug interactions and polypharmacy among elderly patients in Jordan

Polypharmacy and the Contributing Factors Among Elderly Patients in Shashemene Referral Hospital, West Arsi, Oromia Region, Ethiopia

Examining the relationship between depression and medication adherence among elderlies suffering from cardiovascular disease referring to the clinics affiliated with Kermanshah University of Medical Sciences: A cross‐sectional study

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