Prevalence and correlates of depression among patients with chronic kidney disease

Adesokun, Olufisayo; Okeafor, Chukwuma Ugochukwu; Stanley, P C

doi:10.4103/jesnt.jesnt_40_19

Cited by 3 publications

(7 citation statements)

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“…Our study revealed a notably high prevalence of depression among HD patients, with 61.5% scoring positive on the PHQ-9 and 37.5% displaying signs of depression based on the HADS-D. These rates are consistent with studies in Africa (44% to 72.5%) [7,9,10,39] and Asia (42.9% to 80.4%) [1,[40][41][42], as well as reports from Netherlands, Nigeria, and Spain (34.8%, 35%, and 37%, respectively) [43][44][45]. This aligns with a systematic review's depression prevalence range (22.8% to 39.3%) [46].…”

Section: Discussionsupporting

confidence: 87%

The Interplay of Anxiety, Depression, Sleep Quality, and Socioeconomic Factors in Somali Hemodialysis Patients

Kose,

Mohamed

2024

Brain Sciences

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Objective: This study aimed to assess anxiety, depression, and sleep quality in kidney failure patients receiving hemodialysis (HD) in Somalia and examine the relationship between anxiety, depression, and sleep quality. Methods: We conducted a study with 200 kidney failure patients on HD treatment for over 3 months. Participants completed sociodemographic questionnaires, the Patient Health Questionnaire-9 (PHQ-9), the Hospital Anxiety and Depression Scale (HADS), the Insomnia Severity Index (ISI), and the Pittsburgh Sleep Quality Index (PSQI). Results: Among the 200 participants (mean age = 52.3; SD = 14.13), 58.5% were men, 64% had CKD for 1–5 years, and 52.6% received HD for 1–5 years. Depressive symptoms were found in 61.5% (PHQ-9) and 37.5% (HADS depression subscale) of HD patients. Poor sleep quality (PSQI) was observed in 31.5% and significantly correlated with PHQ-9 (rs = 0.633), HADS anxiety (rs = 0.491), and HADS depression (rs = 0.529). The ISI score correlated significantly with PHQ-9 (rs = 0.611), HADS anxiety (rs = 0.494), and HADS depression (rs = 0.586). All PSQI components correlated with depression and anxiety, except sleep medication use. Hierarchical regression analysis revealed that HADS anxiety (β = 0.342) and HADS depression (β = 0.372) predicted ISI scores. HADS anxiety (β = 0.307) and HADS depression (β = 0.419) predicted PSQI scores. Conclusions: Higher anxiety and depression levels negatively correlated with various dimensions of sleep quality in kidney failure patients. Early identification and appropriate management of these psychological disturbances are crucial for enhancing patients’ overall quality of life.

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Section: Discussionsupporting

confidence: 87%

The Interplay of Anxiety, Depression, Sleep Quality, and Socioeconomic Factors in Somali Hemodialysis Patients

Kose,

Mohamed

2024

Brain Sciences

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“…Participants (3 studies) from AFR [30,58,70]; 4,295 (14 studies) from EUR [31,33,34,36,39,43,56,61,66,68,75,78,80,82]; 3,962 (17 studies) from AMR [22,23,24,25,26,29,32,35,38,45,53,55,62,65,67,69,77]; 679 (7 studies) from EMR [40,49,51,60,64,74,81]; 846 (7 studies) from SEAR [28,47,50,59,71,73,79], and 69,660 (13 studies) from the WPR. [27,37,41,42,44,46,48,52,54,57,63,72,76] Figure 2 shows the geographical distribution of the continents of the included studies.…”

Section: Resultsmentioning

confidence: 99%

“…The clinical diagnostic criteria included those of the DSM (20 studies, 2,028 participants) [23,26,27,28,32,34,35,42,46,49,56,60,66,67,70,72,73,74,76,78] ICD (5 studies, 69,954 participants) [25,37,47,71,79] SCID (15 studies, 1,435 participants)[22,33,39,40,43,48,51,53,54,56,57,59,61,65,82], and MINI (21 studies, 6,274 participants). [24,29,30,31,36,38,41,44,45,50,52,55,58,62,64,68,69,75,77,80,81] The sample size of the component studies ranged from 20 [70] to 67,866 [37] patients, with the proportion of women ranging from 0% [25] to 68% [74]. The mean age of the participants ranged from 11.0 years [60] to 76.3 years [77].…”

Section: Resultsmentioning

confidence: 99%

“…Most of the studies had medium methodological quality (68.9%, n = 42) (Table 1); 14 studies (22.9%) were of high quality, including three studies from the Americas [23,25,77], one study from the African region[30], two studies from the Western Pacific region[43,76], three studies from the Eastern Mediterranean region [64,74,81], three from the European region [61,75,80] and two studies from South East Asia. [71,79] Table 1 summarises data extracted from the constituent articles.…”

Section: Resultsmentioning

confidence: 99%

“…Patients and/or the public were not involved in the design, conduct, reporting, or dissemination plans of this research. participants (3 studies) from AFR [30,58,70]; 4,295 (14 studies) from EUR [31,33,34,36,39,43,56,61,66,68,75,78,80,82]; 3,962 (17 studies) from AMR [22,23,24,25,26,29,32,35,38,45,53,55,62,65,67,69,77]; 679 (7 studies) from EMR [40,49,51,60,64,74,81]; 846 (7 studies) from SEAR [28,47,50,59,71,73,79], and 69,660 (13 studies) from the WPR. [27,…”

Section: Patient and Public Involvementmentioning

confidence: 99%

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Global Prevalence of Depression in Chronic Kidney Disease: A Systematic Review and Meta-Analysis

Adejumo,

Edeki,

Dapo

et al. 2023

Preprint

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BackgroundChronic kidney disease (CKD) is commonly associated with psychosocial problems, especially depression, contributing to poor overall outcomes in CKD patients. Depression has not been given adequate priority in the management of CKD despite its significant adverse impact.ObjectivesThis systematic review and meta-analysis determined the pooled prevalence of clinical depression in the global CKD population and sub-populations.DesignA systematic search of PubMed, African Journals Online (AJOL), and EMBASE was undertaken to identify published articles with relevant data between 1989 and 2022. The pooled prevalence of clinical depression in the global CKD population was determined using random effects meta-analytic techniques.ParticipantsGlobal adult and paediatric CKD populationResultsEligible Sixty-one articles were included in this review, comprising 79,691 CKD patients from 26 countries. The participants’ mean age ranged from 11.0 to 76.3 years. Most (68.9%) of the studies had medium methodological quality. The overall pooled prevalence of depression was 27.6% (95% CI: 23.9–31.5%). Studies using Diagnostic Statistical Manual (DSM), International Classification of Disease, Mini-International Neuropsychiatric Interview and Structured Clinical Interview for DSM disorder returned a pooled prevalence of 31.7%, 39.6%, 23.3%, 25.1%, respectively; p=0.09. There was significant difference in the pooled prevalence of CKD across the various continents; p=0.01.The prevalence of depression was higher among patients on chronic haemodialysis compared to those in pre-dialysis (31.1% versus 18.9%; p=0.02), and among those on hemodialysis compared to peritoneal dialysis (31.9% versus 20.4%; p=0.03). There was no significant difference between adults and children (28.0% versus 15.9%, p=0.17).ConclusionDepression is a common disorder in patients with CKD. The findings of this study have brought to the fore the need for clinicians to make deliberate efforts to evaluate CKD patients for depression, especially those with advanced stages of the disease.The study protocol was registered with PROSPERO (CRD42022382708)Strengths and LimitationsThe pooled prevalence of depression in this study correctly represents the magnitude of the depression in the CKD population because it included only studies where depression was diagnosed clinically.This review involved the global population of both adult and paediatric patients with pre-dialysis and dialytic kidney disease.Only a few studies in this review determined the prevalence of depression in the early stages of CKD.Studies reporting depression prevalence among kidney transplant patients were not included in this review, and the number of studies in the paediatric population was limited.

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Global prevalence of depression in chronic kidney disease: a systematic review and meta-analysis

Adejumo,

Edeki,

Sunday Oyedepo

et al. 2024

J Nephrol

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Prevalence and correlates of depression among patients with chronic kidney disease

Cited by 3 publications

References 0 publications

The Interplay of Anxiety, Depression, Sleep Quality, and Socioeconomic Factors in Somali Hemodialysis Patients

The Interplay of Anxiety, Depression, Sleep Quality, and Socioeconomic Factors in Somali Hemodialysis Patients

Global Prevalence of Depression in Chronic Kidney Disease: A Systematic Review and Meta-Analysis

Global prevalence of depression in chronic kidney disease: a systematic review and meta-analysis

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