Prevalence and Clinical Implications of Scleroderma-Specific Autoantibodies in Seronegative Patients with Sicca Complaints
Nikolaos Marketos,
Clio P. Mavragani
Abstract:Introduction:
Previous studies have revealed the presence of anticentromere antibodies in patients with Sjögren’s syndrome (SS), predominantly in those serologically negative for antibodies against Ro/SSA and La/SSB antigens (seronegative). The prevalence and clinical significance of specific autoantibodies for Systemic Sclerosis (SSc) in seronegative patients with sicca complaints (dry eyes, dry mouth) have not yet been studied.
Aim of the study:
Investigate the preval… Show more
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