Prevalence and characteristics of three clinical phenotypes of chronic obstructive pulmonary disease (COPD)

Abstract

In COPD, emphysematous patients present worse pulmonary function and greater dyspnea, although there were no differences in the use of hospital health care resources. The greater comorbidity in Group 2 patients may require specific strategies in this subgroup of patients.

Overlap of Asthma and Chronic Obstructive Pulmonary Disease in Patients in the United States: Analysis of Prevalence, Features, and Subtypes (Preprint)

“…If this was accurate, and assuming that all ACO diagnoses were confirmed by medical record review (100%), under this scenario the estimated ACO prevalence would be 11%, which is consistent with a prior observational study. [11] Our findings of a greater comorbidity burden, medication use, and costs in the claims-positive ACO cohort compared with the claims-positive asthma and COPD cohorts were consistent with prior studies. [18] However, the lower costs observed in the confirmed ACO cohort differed from prior studies that showed ACO patients with higher resource utilization and costs.…”

“…[9,11] These discrepancies between our study and prior studies might be attributed, in part, to the quantity and quality of available medical records.…”

“…[7] Asthma-COPD overlap (ACO; previously referred to as asthma-COPD overlap syndrome) is characterized by persistent airflow limitation consistent with COPD, together with several distinguishing features of asthma. [7] Prevalence estimates range from 5.5% to 55%, [8][9][10][11][12][13][14] likely attributable to differences in diagnostic criteria for asthma and COPD, [5] and other factors, including age and gender. [15] Despite a growing body of literature, no standard exists to identify the syndrome and there is no consensus definition.…”

Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care

“…A small pro- 17,41,48 . An important phenotype is COPD overlapping bronchial asthma that is characterised by the presence of either 2 major criteria, or 1 major and at least 2 minor criteria showing a persistent combination of clinical presentation that is typical for both conditions 3,8,42,[49][50][51] . Table 1 gives an overview of those 6 basic COPD phenotypes, which occasionally might occur simultaneously in clinical practice (e.g.…”

Estimación de la prevalencia de los fenotipos en pacientes con enfermedad pulmonar obstructiva crónica. Estudio ADEPOCLE

“…En los servicios de neumología el 43,2% presentó fenotipo enfisematoso, el 44,7% bronquitis crónica y el 12,1% FMEA (23). En nuestra opinión estos estudios, con una muestra pequeña y de pacientes más graves seguidos o ingresados en el medio hospitalario, sobreestiman la verdadera prevalencia de los diferentes fenotipos clínicos.…”