Prevalence and Characteristics of Central Compared to Obstructive Sleep Apnea: Analyses from the Sleep Heart Health Study Cohort

Abstract

This is the largest community-based study of the prevalence and characteristics of CSA to date and demonstrates a prevalence of CSA that is intermediate to those previously noted. Contrary to prior data from clinic based samples, individuals with heart failure were much more likely to have OSA than CSA.

Association between central sleep apnea and left ventricular structure: the Multi‐Ethnic Study of Atherosclerosis

“…Reflecting the community sample and cohort design (free of known CVD at exam 1), only 23 participants (1.5% of the sample) had an LVEF < 45%. CSA was identified in 27 participants (approximately 2%, comparable to other community samples; Donovan and Kapur, ). Mean CAI was 5.1 ± 5.5 (range: 0–19) in those with CSA, with seven meeting the CSA definition because of the occurrence of CSB with a low CAI.…”

“…The limitations include the cross‐sectional design as well as the relatively low prevalence of both CSA and reduced LVEF, a reflection of a cohort free of CVD at the time of recruitment. However, the prevalence of CSA in this sample is comparable to that of other community samples, such as the Sleep Heart Health Study (Donovan and Kapur, ). Additionally, information to further characterize CSA (such as history of opiate use, duration of CSB and cycle length) was not available.…”

Exome-Wide Meta-Analysis Identifies Rare 3′-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea

“…Another limitation of using questionnaire data is that the discrimination between OSA, central sleep apnea and mixed sleep apnea is not possible. Although the prevalence of central sleep apnea is generally much lower than OSA in particular in general population samples (Donovan and Kapur, 2016 ). Another limitation is that our findings might not be generalizable to other populations as all studies used in this analysis are predominantly European or European American populations.…”

Continuous professional development: elevating sleep and breathing disorder education in Europe

“…Limited data have been reported on CSA and non-obstructive sleep-related hypoventilation, which have received considerable interest in the sleep field within the past 10 years. Even if their prevalence was noted to be quite low relative to the prevalence of OSA [7], they are quite common in specific subpopulations [8][9][10].…”