Prevalence and association of human parvovirus B19V with hepatitis B and C viruses in Nigeria

Abstract

Background In the course of setting up the National Mesothelioma Surveillance Program (PNSM), established in France in 1998, the question arose as to the most suitable method of assessing occupational exposure. The aim of this study was to define the most suitable rating method for assessing occupational asbestos exposure in order to assess medico‐social care. Method The study included 100 subjects—50 cases of mesothelioma and 50 controls—randomly selected and representing 457 jobs held. Job asbestos exposure was assessed by a six‐expert panel using two methods: “by job” rating, where all the jobs in were assessed regardless of the subjects; and “by subject” rating, where all the jobs of a subject were assessed at the same time. Consensus was obtained and subjects' exposure was calculated for each rating. Then, two internal experts assessed job asbestos exposure with the “by subject” rating. Kappa coefficients were used to measure agreement between the ratings. Results Agreement between “by job” and “by subject” ratings was very good for subject probability of exposure (kappa = 0.84) and cumulative exposure index (kappa = 0.80). Agreement between the six‐expert panel and the two internal experts was good for subject exposure (kappa for probability = 0.71; kappa for cumulative exposure index= 0.68). Conclusion This study shows that the two rating systems have good or very good agreement. These results validate the routine use in the PNSM of the “by subject” rating, with the advantage of being convenient and quick to provide feedback on occupational asbestos exposure to mesothelioma cases for compensation. Am. J. Ind. Med. 55:440–449, 2012. © 2012 Wiley Periodicals, Inc.

Detection of parvovirus B19 IgM in patients with sickle cell disease in Lagos, Nigeria

“…The prevalence of 4% and 13.2% were observed among pregnant women in Oyo State [18] and Nasarawa State [19], respectively. Though this study showed a high prevalence of anti-B19V IgM among SCD patients, it was conversely lower than the findings of few other Nigerian studies, including Iwalokun et al [9] in which 17.8% was recorded; Opaleye et al [20] also recorded 32% among a non-hepatitis control group. These variations in the prevalence of anti-B19V IgM may not be unconnected with the characteristics of the populations studied, the sample sizes used in these studies, and the assay kits' sensitivities and specificities.…”

Prevalence of Human Parvovirus B19, Bocavirus, and PARV4 in Blood Samples from the General Population of China and Lack of a Correlation between Parvovirus and Hepatitis B Co-Infection

“…B19 was also co-detected in the sera of HBV-infected patients. A significant correlation exists between HBV/B19 co-infection using serum samples from Vietnamese and Nigerian subjects [17], [18]. However, the data in our study did not support the conclusion that B19 infection increased the frequency of HBV co-infection.…”

“…Co-infection of parvovirus B19 and PARV4 with HBV or hepatitis C (HCV) has been observed in patients with acute and chronic hepatitis [17], [18]. In the southern region of China, HBV infection is endemic, with an HBsAg seroprevalence of approximately 7–9% [21], [22]; however, the seroprevalence of HPAV among the HBV infection individuals in this area is unknown.…”

Co-infection of human parvovirus B19 with Plasmodium falciparum contributes to malaria disease severity in Gabonese patients

“…B19V-genotype 1, and especially B19V-genotype 1A, was the most prevalent genotype in Gabonese children. This is in accordance with previous studies showing a predominance of B19V-genotype 1 worldwide [31,35,48,49]. Interestingly, B19V genotype 2 was found in 28.6% of the young Gabonese children.…”