Prevalence and associated factors of vernal keratoconjunctivitis among children in Gondar city, Northwest Ethiopia

Hayilu, Dereje; Legesse, Kbrom; Lakachew, Natinael; Asferaw, Mulusew

doi:10.1186/s12886-016-0345-7

Cited by 29 publications

(35 citation statements)

References 13 publications

(11 reference statements)

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“…7 The Hayilu D et al also found an association between family history of non-ocular allergic disease such as asthma, atopic rhinitis and VKC. 11 In present study, the most common presenting feature of itching (100%) supports the dictum, 'no itching, no vernal catarrh'. Apart from this, redness was found in 96 (61.93%) patients, watering in 78 (50.32%) patients and thick discharge in 65 (41.93%) patients.…”

Section: Discussionmentioning

confidence: 57%

Hospital based study of demography and clinical picture of vernal keratoconjunctivitis

et al. 2017

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Background: Vernal Keratoconjunctivitis (VKC) is common cause of ocular morbidity in children living in tropical countries. Its diagnosis is based on signs and symptoms of the disease. The study was undertaken to stress upon the demography and clinical presentation of VKC.Methods: Retrospective pre-formed proforma of 155 patients of VKC, who were detected at random in the out - patient department of ophthalmology, ASCOMS, Jammu from May 2016 to April 2017, were analyzed.Results: Mean age at presentation was 10.31 years +4.05. The Male: Female ratio was 4.96:1. Majority of patients reported in the month of May. Mixed type of VKC was predominant. Personal or family history of allergy was seen in 5.8% of patients. Itching (100%) was commonest symptom and palpaberal papillae were commonest sign seen in 78.70% of patients.Conclusions: Clinical pattern of VKC seen in hot and dry climate of Northern India is like that seen in other parts of country.

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Section: Discussionmentioning

confidence: 57%

Hospital based study of demography and clinical picture of vernal keratoconjunctivitis

et al. 2017

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“…The prevalence of VKC varies greatly and increases with vicinity to the equator. In Scandinavian countries, prevalence is close to 0%, whereas it reaches 0.27% in Italy and is higher still in Africa, with a reported prevalence of 6% in Ethiopia . Although the causes of VKC are still unclear, there is a strong correlation with exposure to sunlight, which exacerbates the disease …”

Section: Introductionmentioning

confidence: 99%

“…There are three forms of VKC tarsal, limbal, and mixed. The tarsal form is characterized by the presence of papillae in the upper tarsal lid, and the limbal form by gelatinous infiltrate in the limbus and Horner‐Trantas dots …”

Section: Introductionmentioning

confidence: 99%

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Role of ocular cytology in vernal keratoconjunctivitis

Bruschi

Ghiglioni

Osnaghi

et al. 2019

Immunity Inflam & Disease

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Background Children with vernal keratoconjunctivitis (VKC) present symptoms that are similar to other ocular allergies, but more pronounced, and are controlled using topical steroids. To avoid excessive and prolonged use of topical steroid eye drops, over the past 20 years galenic eye drops of cyclosporine with a concentration of 1% to 2% and tacrolimus with a concentration of 0.1% have been introduced as a treatment for the severe and unresponsive forms. The main symptoms of VKC occur most frequently during the spring and tend to get worse during the summer, meaning that affected children tend to avoid exposure to sunlight. The aim of this study was to assess the most common cell types present in the conjunctiva of children with VKC, how ocular treatment can influence them, and whether affected children express a typical conjunctival pattern, which could be useful as a pathognomonic pattern of VKC, allowing us to study this rare eye disease. Method This was a cohort study of 56 children, of whom 17 were not receiving any treatment at the time of testing, 14 were using steroid eye drops or had taken them in the previous 10 days, and 25 were treated with cyclosporine eye drops or tacrolimus eye drops 0.1%. Result Children in group 1 (no topical therapy) express more epithelial cells, neutrophils, mast cells, eosinophils, and lymphocytes than the other two groups. Conclusion Given the ease of performance, when conducting further longitudinal studies, the conjunctival cytology examination could be used, on the one hand, to diagnose VKC, especially when the clinical diagnosis is uncertain, and, on the other, to follow disease evolution and monitor the response to topical treatment.

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“…It is relatively rare in Western Europe 11 but the prevalence and severity increases in warm climates. 12 Classically it presents in the spring pollen season, but acute exacerbations can occur at any time after exposure to allergens. In vernal keratoconjunctivitis, goblet cells are increased, causing copious mucus production.…”

Section: Rarer Causesmentioning

confidence: 99%