Prevalence and associated factors of DSM-V insomnia in Norway: the Nord-Trøndelag Health Study (HUNT 3)

Uhlig, Benjamin Langsæter; Sand, Trond; Ødegård, Siv Steinsmo; Hagen, Knut

doi:10.1016/j.sleep.2014.01.018

Cited by 88 publications

(84 citation statements)

References 47 publications

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“…may have emerged later during the course of follow-up, which may have influenced the outcome. Finally, the participation rate was not very high (63%) and generalizations of the results must be made with caution as both mortality rates [54] and symptom levels [55] are higher among non-participants.…”

Section: Discussionmentioning

confidence: 99%

Midlife insomnia and subsequent mortality: the Hordaland health study

et al. 2014

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BackgroundPrevious research suggests a possible link between insomnia and mortality, but findings are mixed and well-controlled studies are lacking. The aim of the current study was to examine the effect of insomnia in middle age on all-cause mortality.MethodsUsing a cohort design with 13-15 years follow-up, mortality registry data were linked to health information obtained during 1997-99, as part of the community-based Hordaland Health Study (HUSK), in Western Norway. 6,236 participants aged 40–45 provided baseline information on self- reported insomnia using the Karolinska Sleep Questionnaire Scale (defined according to the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), sociodemographic factors, health behaviors, shift/night-work, obstructive sleep apnea symptoms, sleep duration, sleep medication use, anxiety, depression, as well as a range of somatic diagnoses and symptoms. Height, weight and blood pressure were measured. Information on mortality was obtained from the Norwegian Cause of Death Registry.ResultsInsomnia was reported by 5.6% (349/6236) at baseline and a significant predictor of all-cause-mortality (hazard ratio [HR] = 2.74 [95% CI:1.75-4.30]). Adjusting for all confounders did not attenuate the effect (HR = 3.34 [95% CI:1.67-6.69]). Stratifying by gender, the effect was especially strong in men (HR = 4.72 [95% CI:2.48-9.03]); but also significant in women (adjusted HR = 1.96 [95% CI:1.04-3.67]). The mortality risk among participants with both insomnia and short sleep duration (<6.5 hours) was particularly high, whereas insomnia in combination with normal/greater sleep duration was not associated with mortality.ConclusionsInsomnia was associated with a three-fold risk of mortality over 13-15 years follow-up. The risk appeared even higher in males or when insomnia was combined with short sleep duration, although such unadjusted subgroup analyses should be interpreted with caution. Establishing prevention strategies and low-threshold interventions should consequently be a prioritized task for public health policy.

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Section: Discussionmentioning

confidence: 99%

Midlife insomnia and subsequent mortality: the Hordaland health study

et al. 2014

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“…More specifically, when standardized criteria are used (American Academy of Sleep Medicine, 2014;American Psychiatric Association, 2013), it is estimated that more than half of patients with PD suffered from insomnia disorder (ID) with deleterious effects on quality of life (Sobreira-Neto et al, 2017). ID is therefore a common non-motor complication which warrants particular attention in PD (Uhlig, Sand, Ødegård, & Hagen, 2014).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of cognitive behavioral therapy for insomnia comorbid to Parkinson's disease: A focus on psychological and daytime functioning with a single‐case design with multiple baselines

et al. 2019

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Objective To test the efficacy of cognitive behavioral therapy for insomnia (CBT‐i) in Parkinson's Disease (PD) and to evaluate its impact on indices of daytime and psychological functioning. Method Fifteen patients with insomnia disorder (ID) comorbid to PD were enrolled in a single‐case design with multiple baselines. Total wake time, sleep efficiency, and daytime sleepiness were recorded on a sleep diary. Self‐reported measures of insomnia, anxiety and depressive symptoms, health‐related quality of life, and psychological variables perpetuating ID were completed. All patients also underwent a clinical interview for ID diagnosis. Results CBT‐i was associated with significant changes in sleep variables and ID criteria. Significant positive treatment‐related effects were also noted for all indices of daytime and psychological functioning, and for variables perpetuating ID. All of these improvements were well maintained at 3‐month follow‐up. Conclusion CBT‐i is a promising therapeutic avenue for patients with PD.

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“…Sleep quality has been frequently used as a single indicator encompassing a collection of sleep measures, such as: total sleep time, sleep-onset latency, degree of fragmentation, total wake time, sleep efficiency, and sometimes sleep-disruptive events such as spontaneous arousals or apnea (Krystal and Edinger, 2008). Self-reported sleep quality is affected by gender and age; women and older people are more likely to report lower sleep quality and a higher number of sleep problems (Madrid-Valero et al, 2017; ª 2017 European Sleep Research Society Ohayon et al, 2004;Uhlig et al, 2014;Zhang and Wing, 2006), and it seems to be more closely associated to psychological distress than duration alone (Supartini et al, 2016). Sleep quality also appears to be related to BMI through an inverse relationship (Hung et al, 2013;Kim, 2015), although the opposite has also been reported (Gildner et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Sleep quality and body mass index: a co‐twin study

Madrid‐Valero

Martínez-Selva

Ordoñana

2017

Journal of Sleep Research

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There is a consistent relationship between body mass index and sleep quality. However, the directionality and possible confounding factors of this relationship are unclear. Our aim is to confirm the association between sleep quality and body mass index, independent of possible genetic confounding, as well as to provide some indirect inferences about the directionality of this association. The co-twin study design was used to analyse the body mass index-sleep relationship in a sample of 2150 twins. We selected two parallel sub-samples of twins discordant for body mass index (n = 430 pairs), or discordant for sleep quality (n = 316 pairs). Sleep quality and body mass index showed an inverse relationship (b = 0.056, P = 0.032) in the global sample. When twins discordant for body mass index were selected, this association maintained a similar effect size and statistical significance, at all levels of the case-control analysis (all discordant pairs b = 0.173, P < 0.001; dizygotic twins b = 0.174, P = 0.002; monozygotic twins b = 0.173, P = 0.050). Nevertheless, when twin pairs were selected on the basis of their discordance for sleep quality, the association between body mass index and sleep quality appeared weaker and lost significance (b = 0.021, P = 0.508). The analyses including only dizygotic (b = 0.028, P = 0.526) or monozygotic (b = 0.001, P = 0.984) pairs produced similar non-significant results. Our results confirm the relationship between sleep quality and body mass index, even after applying high levels of control, including genetic factors. Moreover, this study suggests a possible directionality of this relationship, such that sleep quality would strongly affect body mass index, while the opposite would be less robust and consistent in non-clinical samples.

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Prevalence and associated factors of DSM-V insomnia in Norway: the Nord-Trøndelag Health Study (HUNT 3)

Cited by 88 publications

References 47 publications

Midlife insomnia and subsequent mortality: the Hordaland health study

Midlife insomnia and subsequent mortality: the Hordaland health study

Efficacy of cognitive behavioral therapy for insomnia comorbid to Parkinson's disease: A focus on psychological and daytime functioning with a single‐case design with multiple baselines

Sleep quality and body mass index: a co‐twin study

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