Prevalence and associated factors of depression and anxiety among Chinese diabetic retinopathy patients: A cross-sectional study

Abstract

The purposes of this study were to evaluate the mental health among patients with diabetic retinopathy (DR) and to explore its’ influencing factors. A cross-sectional survey was conducted in Liaoning Province, China. A total of 200 patients volunteered to participate in the survey. Psycho-social variables included stress, self-efficacy, resilience, and social support. logistic regression analysis was used to explore the effect of psycho-social factors on depression and anxiety in DR patients. The prevalence of depression and anxiety was 25% and 13.5% among DR patients. Regression analysis showed that social support had a significant protective effect on depression (95%CI 0.931–0.997) and anxiety (95%CI 0.900–0.995). Stress had a significant acceleration of depression (95%CI 1.055–1.253) and anxiety (95%CI 1.120–1.457). Family history of diabetes (95%CI 1.856–18.057) and other chronic diseases (95%CI 1.485–12.508) were risk factors for anxiety. The high prevalence of depression (25.0%) and anxiety (13.5%) among DR patients should receive more attention in Chinese medical settings. Stress, social support, family history of diabetes and other chronic diseases seemed to be crucial in relation to depressive symptoms. Efficient interventions such as improving social support and decreasing stress with patients should be considered by health administrators aiming at alleviating depressive and anxiety among Chinese DR patients.

Disease perception and experience in people with diabetic retinopathy: A qualitative study

“…The participants in this study may have exaggerated their illnesses because of their visual impairment and concerns about blindness, which may have led to a variety of negative emotions. Previous studies have demonstrated that the overall mental health status of patients with DR patients is low (Xu et al, 2022). Chinese medical institutions should direct more attention to the high prevalence of depression (25.0%) and anxiety (13.5%) in these patients (Xu et al, 2022).…”

“…Previous studies have demonstrated that the overall mental health status of patients with DR patients is low (Xu et al, 2022). Chinese medical institutions should direct more attention to the high prevalence of depression (25.0%) and anxiety (13.5%) in these patients (Xu et al, 2022). This study found that the suffering of the respondents was more serious than previously thought.…”

Mingmu Xiaoyao granules regulate the PI3K/Akt/mTOR signaling pathway to reduce anxiety and depression and reverse retinal abnormalities in rats

“…The close association between many retinal diseases and psychosomatic diseases may be related to the patients’ reduced visual function ( Moschos et al, 2015 ; Vu et al, 2021 ), self-assessment of health and quality of life due to the condition ( Vu et al, 2021 ), and dependence on family caregivers ( Jin et al, 2021 ). In addition, high mental stress ( Xu et al, 2022 ), low income and living alone ( Chen et al, 2018 ) are all risk factors for eye disease associated with psychosomatic disease, but increased social support has a significant protective effect on such patients ( Xu et al, 2022 ). Negative emotions such as anxiety and depression can further exacerbate the progression of eye disease and anxiety reportedly increases the risk of glaucoma progression ( Shin et al, 2021 ).…”

“…For instance, neovascular age-related macular degeneration is reported in 26.9% of patients with symptomatic depression and 25.5% with symptomatic anxiety ( Fernandez-Vigo et al, 2021 ), and depressive symptoms are even more common than anxiety symptoms ( Dawson et al, 2014 ). Among patients with diabetic retinopathy (DR), 25% suffer from depression and 13.5% suffer from anxiety ( Xu et al, 2022 ). The incidence of DR is reduced after the use of antidepressants ( Yekta et al, 2015 ).…”

Anxiety and Depression in Patients with Diabetic Retinopathy

“…On the one hand, earlier disease detection and DR prevention are made possible by improved diabetes diagnosis and management D standards. Potential psychological stress may accelerate the progression of DR through biological pathways (9) or through behavioral pathways (10), which can result in poor blood sugar control and increase the risk of DR. On the other hand, psychological factors are significantly related to the occurrence and development of DR (11), active diabetes health management, psychological intervention, and DR can be slowed down (12). In order to prevent and treat visual impairment as well as manage diabetes holistically, it is important to pay attention to psychological aspects and their underlying mechanisms and to act quickly.…”