Prevalence and associated factors of hospitalization for dysglycemia among elderly type 2 diabetes patients: A nationwide study

Abstract

BACKGROUNDThe prevalence of older individuals with type 2 diabetes mellitus (T2DM) is increasing due to the aging population and improved medical care. These patients are very susceptible to disease and treatment-related hospitalizations, resulting in higher health care costs, morbidity, and decreased quality of life. However, data of treatment-related complications, especially dysglycemia-related hospitalizations, are lacking.AIMTo assess the prevalence and associated factors for dysglycemia-related hospitalizations among elderly diabetic patients in Thailand using nationwide patient sample.METHODST2DM patients aged ≥ 65 years who received medical care at public hospitals in Thailand in the year 2014 were included. The prevalence of hospitalization due to dysglycemia within one year was examined. Multivariable logistic regression was performed to assess the independent factors associated with hospitalization due to hypoglycemia and hyperglycemiaRESULTSA total of 11404 elderly T2DM patients were enrolled in this study. The mean age was 72.9 ± 5.5 years. The prevalence of hospital admissions due to diabetic ketoacidosis, hyperosmolar hyperglycemic state, hyperglycemic dehydration syndrome, and hypoglycemia among elderly T2DM patients in the year 2014 was 0.1%, 0.1%, 1.7% and 3.1%, respectively. Increased hospitalization due to hypoglycemia was associated with older age, female sex, had hypertension, dementia, lower body mass index, elevated hemoglobin A1C (HbA1C), decreased kidney function, insulin use. Increased hospitalization due to hyperglycemia was associated with dementia, depression, lower body mass index, elevated HbA1C, and insulin use.CONCLUSIONThe prevalence of dysglycemia-related hospitalization in elderly T2DM patients in Thailand was 4.9%. Close monitoring of blood glucose should be provided in high-risk patients for prevention and early detection for these complications.

Impending Low Intake Dehydration at Admission to A Geriatric Ward- Prevalence and Correlates in a Cross-Sectional Study

“…High blood glucose levels lead to osmotic diuresis and decreased hydration in the body. Hyperglycemic dehydration syndrome is one of the important reasons for hospitalizations among older type 2 diabetes patients [44]. The proper treatment of diabetes should be a priority in the above case, and-in parallel with this-water and electrolyte deficiencies should be supplemented.…”

SGLT2 Inhibitors and Kidney Outcomes in Patients with Chronic Kidney Disease

“…Diabetes mellitus and associated conditions including hypertension, obesity, and atherosclerosis significantly contribute to progression of chronic kidney disease (CKD), cardiovascular health, and overall mortality [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. Diabetes is an evolving global pandemic with diabetic kidney disease accounting for 44.5% of new end-stage kidney disease (ESKD) cases [ 1 , 2 ].…”

Hypoglycemia and the risk of cognitive impairment and dementia in elderly and senile patients with type 2 diabetes

“…Деменция также является одним из факторов риска развития гипогликемии [28]. Кроме того, наличие деменции увеличивает риск госпитализаций больных СД2 и, как следствие, расходов на здравоохранение [29]. Так, в исследовании W. Kaewput еt al.…”

“…Так, в исследовании W. Kaewput еt al. [29], в котором приняли участие 11 404 пациента с СД2, показано, что больные с наличием деменции нуждались в более частой госпитализации, по сравнению с пациентами без деменции, в случае развития гипогликемии (отношение шансов (ОШ) 6,27; 95% ДИ 2,13-18,43; р=0,001) [29]. В свою очередь, частые эпизоды гипогликемии у пациентов старших возрастных групп представляют реальную опасность, так как способствуют появлению ряда неблагоприятных последствий, в том числе развитию КН и их прогрессированию вплоть до развития деменции [30].…”